Search Results - "Choi, John"

Mechanisms of immunotherapy resistance: lessons from glioblastoma by Jackson, Christopher M., Choi, John, Lim, Michael

“…Glioblastoma (GBM) is the deadliest form of brain cancer, with a median survival of less than 2 years despite surgical resection, radiation, and chemotherapy…”
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Lumbar arthroplasty for treatment of primary or recurrent lumbar disc herniation by Rossi, Vincent, Maalouly, Joseph, Choi, John Y. S.

“…Purpose Microdiscectomy is the current gold standard surgical treatment for primary lumbar disc herniations that fail non-surgical measures. Herniated nucleus…”
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Combination immunotherapy strategies for glioblastoma by Chan, Hok Yee, Choi, John, Jackson, Christina, Lim, Michael

“…Introduction Despite recent advances in treatment for a number of cancers with immune checkpoint blockade (ICB), immunotherapy has had limited efficacy in…”
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Hyperspectral phasor analysis enables multiplexed 5D in vivo imaging by Cutrale, Francesco, Trivedi, Vikas, Trinh, Le A, Chiu, Chi-Li, Choi, John M, Artiga, Marcela S, Fraser, Scott E

“…Hyper-Spectral Phasors allow unmixing of multiple signals even under conditions with low signal-to-noise ratios, and they enable highly multiplexed 5D imaging…”
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Deep and fast live imaging with two-photon scanned light-sheet microscopy by Truong, Thai V, Supatto, Willy, Koos, David S, Choi, John M, Fraser, Scott E

“…Two-photon excitation in scanned light-sheet microscopy allows deeper imaging than the one-photon implementation and faster three-dimensional imaging of…”
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LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors by Cheng, Ying, Chikwava, Kudakwashe, Wu, Chao, Zhang, Haibing, Bhagat, Anchit, Pei, Dehua, Choi, John K, Tong, Wei

“…Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a high-risk ALL commonly associated with alterations that affect the tyrosine kinase…”
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Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Combination With Fludarabine and Cytarabine, in Pediatric Relapsed or Refractory Acute Leukemia by Alexander, Thomas B, Lacayo, Norman J, Choi, John K, Ribeiro, Raul C, Pui, Ching-Hon, Rubnitz, Jeffrey E

“…Purpose To characterize the toxicity, pharmacokinetics, and pharmacodynamics of selinexor, a selective inhibitor of nuclear export, when combined with…”
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Improved CNS Control of Childhood Acute Lymphoblastic Leukemia Without Cranial Irradiation: St Jude Total Therapy Study 16 by Jeha, Sima, Pei, Deqing, Choi, John, Cheng, Cheng, Sandlund, John T, Coustan-Smith, Elaine, Campana, Dario, Inaba, Hiroto, Rubnitz, Jeffrey E, Ribeiro, Raul C, Gruber, Tanja A, Raimondi, Susana C, Khan, Raja B, Yang, Jun J, Mullighan, Charles G, Downing, James R, Evans, William E, Relling, Mary V, Pui, Ching-Hon

“…Despite contemporary treatment, up to 10% of children with acute lymphoblastic leukemia still experience relapse. We evaluated whether a higher dosage of…”
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Bortezomib with standard chemotherapy for children with acute myeloid leukemia does not improve treatment outcomes: a report from the Children's Oncology Group by Aplenc, Richard, Meshinchi, Soheil, Sung, Lillian, Alonzo, Todd, Choi, John, Fisher, Brian, Gerbing, Robert, Hirsch, Betsy, Horton, Terzah, Kahwash, Samir, Levine, John, Loken, Michael, Brodersen, Lisa, Pollard, Jessica, Raimondi, Susana, Kolb, Edward Anders, Gamis, Alan

“…New therapeutic strategies are needed for pediatric acute myeloid leukemia (AML) to reduce disease recurrence and treatment-related morbidity. The Children's…”
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International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia by Hrusak, Ondrej, de Haas, Valerie, Stancikova, Jitka, Vakrmanova, Barbora, Janotova, Iveta, Mejstrikova, Ester, Capek, Vaclav, Trka, Jan, Zaliova, Marketa, Luks, Ales, Bleckmann, Kirsten, Möricke, Anja, Irving, Julie, Konatkowska, Benigna, Alexander, Thomas B., Inaba, Hiroto, Schmiegelow, Kjeld, Stokley, Simone, Zemanova, Zuzana, Moorman, Anthony V., Rossi, Jorge Gabriel, Felice, Maria Sara, Dalla-Pozza, Luciano, Morales, Jessa, Dworzak, Michael, Buldini, Barbara, Basso, Giuseppe, Campbell, Myriam, Cabrera, Maria Elena, Marinov, Neda, Elitzur, Sarah, Izraeli, Shai, Luria, Drorit, Feuerstein, Tamar, Kolenova, Alexandra, Svec, Peter, Kreminska, Olena, Rabin, Karen R., Polychronopoulou, Sophia, da Costa, Elaine, Marquart, Hanne Vibeke, Kattamis, Antonis, Ratei, Richard, Reinhardt, Dirk, Choi, John K., Schrappe, Martin, Stary, Jan

“…Despite attempts to improve the definitions of ambiguous lineage leukemia (ALAL) during the last 2 decades, general therapy recommendations are missing…”
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Microneedle‐Based Local Delivery of CCL22 and IL‐2 Enriches Treg Homing to the Skin Allograft and Enables Temporal Monitoring of Immunotherapy Efficacy by Puigmal, Núria, Dosta, Pere, Solhjou, Zhabiz, Yatim, Karim, Ramírez, Cynthia, Choi, John Y., Alhaddad, Juliano B., Cosme, Ana Paula, Azzi, Jamil, Artzi, Natalie

“…Skin allografts only serve as temporary dressing for patients suffering major burns due to their high immunogenicity and rejection by the immune system,…”
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Adult T-cell leukemia/lymphoma by Qayyum, Sohail, Choi, John K

“…Adult T-cell leukemia/lymphoma is a rare mature CD4(+) T-cell neoplasm caused by the retrovirus human T-lymphotrophic virus type 1. At present there are…”
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A systematic review and meta-analysis of supratotal versus gross total resection for glioblastoma by Jackson, Christina, Choi, John, Khalafallah, Adham M., Price, Carrie, Bettegowda, Chetan, Lim, Michael, Gallia, Gary, Weingart, Jon, Brem, Henry, Mukherjee, Debraj

“…Purpose Due to the infiltrative nature of glioblastoma (GBM) outside of the contrast-enhancing region on MRI, there is interest in exploring supratotal…”
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Fifth Edition of the World Health Organization Classification of Tumors of the Hematopoietic and Lymphoid Tissues: Acute Lymphoblastic Leukemias, Mixed-Phenotype Acute Leukemias, Myeloid/Lymphoid Neoplasms With Eosinophilia, Dendritic/Histiocytic Neoplasms, and Genetic Tumor Syndromes by Choi, John K., Xiao, Wenbin, Chen, Xueyan, Loghavi, Sanam, Elenitoba-Johnson, Kojo S., Naresh, Kikkeri N., Medeiros, L. Jeffrey, Czader, Magdalena

“…This manuscript represents a review of lymphoblastic leukemia/lymphoma (acute lymphoblastic leukemia/lymphoblastic lymphoma), acute leukemias of ambiguous…”
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Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms by Diamond, Eli L, Durham, Benjamin H, Haroche, Julien, Yao, Zhan, Ma, Jing, Parikh, Sameer A, Wang, Zhaoming, Choi, John, Kim, Eunhee, Cohen-Aubart, Fleur, Lee, Stanley Chun-Wei, Gao, Yijun, Micol, Jean-Baptiste, Campbell, Patrick, Walsh, Michael P, Sylvester, Brooke, Dolgalev, Igor, Aminova, Olga, Heguy, Adriana, Zappile, Paul, Nakitandwe, Joy, Ganzel, Chezi, Dalton, James D, Ellison, David W, Estrada-Veras, Juvianee, Lacouture, Mario, Gahl, William A, Stephens, Philip J, Miller, Vincent A, Ross, Jeffrey S, Ali, Siraj M, Briggs, Samuel R, Fasan, Omotayo, Block, Jared, Héritier, Sebastien, Donadieu, Jean, Solit, David B, Hyman, David M, Baselga, José, Janku, Filip, Taylor, Barry S, Park, Christopher Y, Amoura, Zahir, Dogan, Ahmet, Emile, Jean-Francois, Rosen, Neal, Gruber, Tanja A, Abdel-Wahab, Omar

“…Histiocytic neoplasms are clonal, hematopoietic disorders characterized by an accumulation of abnormal, monocyte-derived dendritic cells or macrophages in…”
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Carboxylated branched poly(β-amino ester) nanoparticles enable robust cytosolic protein delivery and CRISPR-Cas9 gene editing by Rui, Yuan, Wilson, David R, Choi, John, Varanasi, Mahita, Sanders, Katie, Karlsson, Johan, Lim, Michael, Green, Jordan J

“…Efficient cytosolic protein delivery is necessary to fully realize the potential of protein therapeutics. Current methods of protein delivery often suffer from…”
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BCL-W has a fundamental role in B cell survival and lymphomagenesis by Adams, Clare M, Kim, Annette S, Mitra, Ramkrishna, Choi, John K, Gong, Jerald Z, Eischen, Christine M

“…Compromised apoptotic signaling is a prerequisite for tumorigenesis. The design of effective therapies for cancer treatment depends on a comprehensive…”
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Assessment of Great Vessels for Anterior Access of L5/S1 Using Patient Positioning by Choi, John, Rhee, Isaac, Ruparel, Sameer

“…Study Design: This was a prospective cross-sectional study.Purpose: The aim was to describe the effect of patient positioning, from supine to lateral decubitus…”
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Sacroiliac Joint Fusion: Fusion Rates and Clinical Improvement Using Minimally Invasive Approach and Intraoperative Navigation and Robotic Guidance by Sarkar, Mehul, Maalouly, Joseph, Ruparel, Sameer, Choi, John

“…This study adopted a retrospective study design. This study was designed to describe the fusion rate and technique and patient subjective improvement after…”
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RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation by Suzuki, Aae, Shin, Jae-Won, Wang, Yuhuan, Min, Sang H, Poncz, Morty, Choi, John K, Discher, Dennis E, Carpenter, Chris L, Lian, Lurong, Zhao, Liang, Wang, Yangfeng, Abrams, Charles S

“…RhoA plays a multifaceted role in platelet biology. During platelet development, RhoA has been proposed to regulate endomitosis, proplatelet formation, and…”
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