Search Results - "Choi, James S."
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Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord
Published in The Journal of experimental medicine (16-06-2021)“…The wound healing process that occurs after spinal cord injury is critical for maintaining tissue homeostasis and limiting tissue damage, but eventually…”
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Myelin and non-myelin debris contribute to foamy macrophage formation after spinal cord injury
Published in Neurobiology of disease (01-02-2022)“…Tissue damage after spinal cord injury (SCI) elicits a robust inflammatory cascade that fails to resolve in a timely manner, resulting in impaired wound…”
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PI3K signaling promotes formation of lipid-laden foamy macrophages at the spinal cord injury site
Published in Neurobiology of disease (01-01-2024)“…After spinal cord injury (SCI), infiltrating macrophages undergo excessive phagocytosis of myelin and cellular debris, forming lipid-laden foamy macrophages…”
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Interaction between subventricular zone microglia and neural stem cells impacts the neurogenic response in a mouse model of cortical ischemic stroke
Published in Nature communications (24-10-2024)“…After a stroke, the neurogenic response from the subventricular zone (SVZ) to repair the brain is limited. Microglia, as an integral part of the distinctive…”
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Single-nucleus RNA sequencing of developing superior colliculus identifies neuronal diversity and candidate mediators of circuit assembly
Published in Cell reports (Cambridge) (26-09-2023)“…The superior colliculus (SC) is a sensorimotor structure in the midbrain that integrates input from multiple sensory modalities to initiate motor commands. It…”
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TNFR2 Signaling Regulates the Immunomodulatory Function of Oligodendrocyte Precursor Cells
Published in Cells (Basel, Switzerland) (15-07-2021)“…Multiple sclerosis (MS) is a neuroimmune disorder characterized by inflammation, CNS demyelination, and progressive neurodegeneration. Chronic MS patients…”
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Ectopic ACTH Production Caused by Metastatic Parotid Gland Acinic Cell Carcinoma
Published in AACE clinical case reports (01-01-2021)“…To present a case of adrenocorticotropic hormone (ACTH) hypersecretion caused by a metastatic acinic cell carcinoma (AcCC) of the parotid. Only 6 cases have…”
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A systematic evaluation of the computational tools for ligand-receptor-based cell–cell interaction inference
Published in Briefings in functional genomics (16-09-2022)“…Abstract Cell–cell interactions (CCIs) are essential for multicellular organisms to coordinate biological processes and functions. One classical type of CCI…”
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Bromodomain and extraterminal domain-containing protein inhibition attenuates acute inflammation after spinal cord injury
Published in Experimental neurology (01-11-2018)“…Inflammation is a major contributor to the secondary damage that occurs after spinal cord injury (SCI). The inflammatory response is coordinated by many…”
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Impaired Bidirectional Synaptic Plasticity in Juvenile Offspring Following Prenatal Ethanol Exposure
Published in Alcoholism, clinical and experimental research (01-10-2019)“…Background The hippocampus is particularly vulnerable to the teratogenic effects of prenatal ethanol exposure (PNEE), and hippocampal structural and functional…”
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PR3 ANCA VASCULITIS PRESENTING AS NONRESOLVING PNEUMONIA FOLLOWING COVID-19 INFECTION
Published in Chest (01-10-2024)Get full text
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CONQUERING THE CLOT: A COMPLEX CASE OF MAY-THURNER SYNDROME COMPLICATED BY MASSIVE DVT AND SUBMASSIVE PE
Published in Chest (01-10-2024)Get full text
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Modeling and simulating software acquisition process architectures
Published in The Journal of systems and software (2001)“…In this paper, we describe our efforts to support the modeling and simulation of processes associated with software system acquisition activities. Software…”
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A CASE OF FOLLICULAR LYMPHOMA PRESENTING WITH ANGIOEDEMA
Published in Chest (01-10-2024)Get full text
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Ectopic ACTH Production Caused by Metastatic Parotid Gland Acinic Cell Carcinoma
Published in AACE clinical case reports (01-01-2021)“…OBJECTIVETo present a case of adrenocorticotropic hormone (ACTH) hypersecretion caused by a metastatic acinic cell carcinoma (AcCC) of the parotid. Only 6…”
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