Search Results - "Choi, Hojun"
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Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein–protein interaction module
Published in Nature communications (22-07-2016)“…Nanoparticle-mediated delivery of functional macromolecules is a promising method for treating a variety of human diseases. Among nanoparticles, cell-derived…”
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2
Mesenchymal Stem Cell‐Derived Extracellular Vesicles as Therapeutics and as a Drug Delivery Platform
Published in Stem cells translational medicine (01-09-2019)“…Summary Mesenchymal stem cells (MSCs) are one of the most easily accessible stem cells that can be obtained from various human tissues. They have raised…”
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3
Hyper-inflammatory responses in COVID-19 and anti-inflammatory therapeutic approaches
Published in BMB reports (2022)“…The coronavirus disease 2019 (COVID-19) is an ongoing global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with…”
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4
Strategies for Targeted Delivery of Exosomes to the Brain: Advantages and Challenges
Published in Pharmaceutics (18-03-2022)“…Delivering therapeutics to the central nervous system (CNS) is difficult because of the blood-brain barrier (BBB). Therapeutic delivery across the tight…”
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5
Targeted Delivery of Exosomes Armed with Anti-Cancer Therapeutics
Published in Membranes (Basel) (13-01-2022)“…Among extracellular vesicles, exosomes have gained great attention for their role as therapeutic vehicles for delivering various active pharmaceutical…”
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SLA-1 Genetic Diversity in Pigs: Extensive Analysis of Copy Number Variation, Heterozygosity, Expression, and Breed Specificity
Published in Scientific reports (20-01-2020)“…Swine leukocyte antigens play indispensable roles in immune responses by recognizing a large number of foreign antigens and thus, their genetic diversity plays…”
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7
Hyper-inflammatory responses in COVID-19 and anti-inflammatory therapeutic approaches
Published in BMB reports (31-01-2022)“…The coronavirus disease 2019 (COVID-19) is an ongoing global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with…”
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The complete swine olfactory subgenome: expansion of the olfactory gene repertoire in the pig genome
Published in BMC genomics (15-11-2012)“…Insects and animals can recognize surrounding environments by detecting thousands of chemical odorants. Olfaction is a complicated process that begins in the…”
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Manufacturing Therapeutic Exosomes: from Bench to Industry
Published in Molecules and cells (2022)“…Exosome, a type of nanoparticles also known as small extracellular vesicles are gaining attention as novel therapeutics for various diseases because of their…”
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10
Differential Effects of Dietary Methionine Isomers on Broilers Challenged with Acute Heat Stress
Published in The Journal of Poultry Science (2019)“…In this study, we investigated the effect of methionine isomers (D- and L-methionine) on growth performance, blood metabolite levels, nutrient digestibility,…”
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11
Development of a simultaneous high resolution typing method for three SLA class II genes, SLA-DQA, SLA-DQB1, and SLA-DRB1 and the analysis of SLA class II haplotypes
Published in Gene (15-06-2015)“…The characterization of the genetic variations of major histocompatibility complex (MHC) is essential to understand the relationship between the genetic…”
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12
Quantitative Biodistribution and Pharmacokinetics Study of GMP-Grade Exosomes Labeled with 89Zr Radioisotope in Mice and Rats
Published in Pharmaceutics (24-05-2022)“…For the successful clinical advancement of exosome therapeutics, the biodistribution and pharmacokinetic profile of exogenous exosomes in various animal models…”
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13
Genetic Diversity and mRNA Expression of Porcine MHC Class I Chain-Related 2 (SLA-MIC2) Gene and Development of a High-Resolution Typing Method
Published in PloS one (25-08-2015)“…The genetic structure and function of MHC class I chain-related (MIC) genes in the pig genome have not been well characterized, and show discordance in…”
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14
Lack of Cytosolic Carboxypeptidase 1 Leads to Subfertility due to the Reduced Number of Antral Follicles in pcd3J-/- Females
Published in PloS one (09-10-2015)“…Females homozygous for the Purkinje cell degeneration mutation (pcd) are fertile, although the success rate is much lower than in the wild type. We performed…”
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Abnormal sperm development in pcd(3J)-/- mice: the importance of Agtpbp1 in spermatogenesis
Published in Molecules and cells (01-01-2011)“…Homozygous Purkinje cell degeneration (pcd) mutant males exhibit abnormal sperm development. Microscopic examination of the testes from pcd(3J)-/- mice at…”
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Abnormal sperm development in pcd3J-/- mice: the importance of Agtpbp1 in spermatogenesis
Published in Molecules and cells (2011)“…Homozygous Purkinje cell degeneration ( pcd ) mutant males exhibit abnormal sperm development. Microscopic examination of the testes from pcd 3J -/- mice at…”
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17
Spectral clustering algorithm for real‐time endpoint detection of silicon nitride plasma etching
Published in Plasma processes and polymers (01-06-2023)“…The spectral clustering algorithm (SCA) is developed for endpoint detection (EPD) of Si3N4 plasma etching using optical emission spectroscopy (OES). OES…”
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Characterization of the bovine endogenous retrovirus beta3 genome
Published in Molecules and cells (29-02-2008)“…We recently used degenerate PCR and locus-specific PCR methods to identify the endogenous retroviruses (ERV) in the bovine genome. Using the ovine ERV…”
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Roles of Type I and III Interferons in COVID-19
Published in Yonsei medical journal (01-05-2021)“…Coronavirus disease 2019 (COVID-19) is an ongoing global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Type I and III…”
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Exosome-mediated delivery of active glucocerebrosidase to Gaucher model cells
Published in Molecular genetics and metabolism (01-02-2019)Get full text
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