Search Results - "Choi, Guang J."
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1
Drug Properties Prediction Based on Deep Learning
Published in Pharmaceutics (21-02-2022)“…In recent research on the formulation prediction of oral dissolving drugs, deep learning models with significantly improved performance compared to machine…”
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Deep Learning-Based Prediction of Physical Stability considering Class Imbalance for Amorphous Solid Dispersions
Published in Journal of chemistry (18-03-2022)“…This research is aimed at predicting the physical stability for amorphous solid dispersion by utilizing deep learning methods. We propose a prediction model…”
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3
Antimalarial Drug Predictions Using Molecular Descriptors and Machine Learning against Plasmodium Falciparum
Published in Biomolecules (Basel, Switzerland) (24-11-2021)“…Malaria remains by far one of the most threatening and dangerous illnesses caused by the plasmodium falciparum parasite. Chloroquine (CQ) and first-line…”
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Cocrystal Prediction Using Machine Learning Models and Descriptors
Published in Applied sciences (01-02-2021)“…Cocrystals are of much interest in industrial application as well as academic research, and screening of suitable coformers for active pharmaceutical…”
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Characteristics of indomethacin–saccharin (IMC–SAC) co-crystals prepared by an anti-solvent crystallization process
Published in European journal of pharmaceutics and biopharmaceutics (01-11-2013)“…The creation of co-crystals of various insoluble drug substances has been extensively investigated as a promising approach to improve their pharmaceutical…”
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6
In line NIR quantification of film thickness on pharmaceutical pellets during a fluid bed coating process
Published in International journal of pharmaceutics (17-01-2011)“…Along with the risk-based approach, process analytical technology (PAT) has emerged as one of the key elements to fully implement QbD (quality-by-design)…”
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Combined anti-solvent and cooling method of manufacturing indomethacin–saccharin (IMC–SAC) co-crystal powders
Published in Journal of crystal growth (15-12-2014)“…The anti-solvent approach has been demonstrated as one potential industrial method to produce pharmaceutical co-crystal powders with high purity. In this…”
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Novel Cocrystals of Vonoprazan: Machine Learning-Assisted Discovery
Published in Pharmaceutics (16-02-2022)“…Vonoprazan (VPZ) is the first-in-class potassium-competitive acid blocker (P-CAB), and has many advantages over proton pump inhibitors (PPIs). It is…”
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Paracellular permeation-enhancing effect of AT1002 C-terminal amidation in nasal delivery
Published in Drug design, development and therapy (01-01-2015)“…The identification of permeation enhancers has gained interest in the development of drug delivery systems. A six-mer peptide, H-FCIGRL-OH (AT1002), is a tight…”
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10
Manufacture and characterization of two distinct quasi-polymorphs of empagliflozin
Published in Journal of crystal growth (15-03-2020)“…•A new polymorph of empagliflozin was produced and analyzed by various instruments.•Two polymorphs were differentiated by the derivative analysis of DSC…”
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11
Anti-solvent co-crystallization of carbamazepine and saccharin
Published in International journal of pharmaceutics (25-06-2013)“…Close-up of CBZ/SAC phase solubility diagram in methanol with experiment points. The co-crystal approach has been investigated extensively over the past decade…”
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12
Preparation and Characterization of Aripiprazole Cocrystals with Coformers of Multihydroxybenzene Compounds
Published in Crystal growth & design (06-12-2017)“…A novel co-crystal of aripiprazole (ARI), the active substance in the atypical antipsychotic Abilify, with orcinol (ORC) as a coformer, was prepared,…”
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13
Understanding the Formation of Indomethacin–Saccharin Cocrystals by Anti-Solvent Crystallization
Published in Crystal growth & design (01-05-2013)“…Pharmaceutical cocrystals are a novel drug form with the potential to enhance pharmaceutical properties, including the solubility and dissolution behavior for…”
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14
In Situ Monitoring of Antisolvent Cocrystallization by Combining Near-Infrared and Raman Spectroscopies
Published in Crystal growth & design (02-09-2015)“…In situ monitoring techniques are essential for the control and optimization of the cocrystallization process. In our previous study, we successfully monitored…”
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15
Agomelatine–hydroquinone (1:1) cocrystal: novel polymorphs and their thermodynamic relationship
Published in Acta crystallographica Section B, Structural science, crystal engineering and materials (01-12-2019)“…Polymorphism of active pharmaceutical ingredients (APIs) is of significance in the pharmaceutical industry because it can affect the quality, efficacy and…”
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16
BaTiO3 particles prepared by microwave-assisted hydrothermal reaction using titanium acylate precursors
Published in Materials letters (01-11-1999)“…Experimental variables taken into account were the reaction type (reflux and autoclave), the reaction time and the Ba to Ti ratio in sol solutions. Autoclave…”
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Characteristics of BaTiO3 Particles Prepared by Spray−Coprecipitation Method Using Titanium Acylate-Based Precursors
Published in Chemistry of materials (21-12-1998)“…BaTiO3 particles of ultrafine size and high crystallinity were produced by a spray−coprecipitation technique. To improve stability, titanium isopropoxide was…”
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Quantitative in-line monitoring of solvent-mediated polymorphic transformation of sulfamerazine by near-infrared spectroscopy
Published in Journal of pharmaceutical sciences (01-04-2012)“…The in-line monitoring of pharmaceutical processes with high risk, such as crystallization, has been one of the most popular research topics in recent years…”
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Synthesis and characteristics of near-stoichiometric barium titanate powder by low temperature hydrothermal reaction using titanium tetra(methoxyethoxide)
Published in Journal of materials science (01-09-2000)“…Near-stoichiometric BaTiO3 powders with ultrafine particle size and high crystallinity were prepared by low temperature hydrothermal reaction of Ba(OAc)2 and…”
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20
A novel precursor for the sol-gel and CVD methods to prepare alumina permselective membranes
Published in Journal of materials science (01-03-1998)“…A novel metalorganic compound, Al(OPri)2(etac), was synthesized and used for the preparation of alumina permselective membranes. Membranes were produced by…”
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