Search Results - "Chognard, Gaëlle"

The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation by Chognard, Gaëlle, Bellemare, Lisa, Pelletier, Adam-Nicolas, Dominguez-Punaro, Maria C, Beauchamp, Claudine, Guyon, Marie-Josée, Charron, Guy, Morin, Nicolas, Sivanesan, Durga, Kuchroo, Vijay, Xavier, Ramnik, Michnick, Stephen W, Chemtob, Sylvain, Rioux, John D, Lesage, Sylvie

“…IL-12 and IL-23 cytokines respectively drive Th1 and Th17 type responses. Yet, little is known regarding the biology of these receptors. As the IL-12 and IL-23…”
Get full text

Induced and spontaneous colitis mouse models reveal complex interactions between IL-10 and IL-12/IL-23 pathways by Hurtubise, Raphaël, Audiger, Cindy, Dominguez-Punaro, Maria C., Chabot-Roy, Geneviève, Chognard, Gaëlle, Raymond-Marchand, Laurence, Coderre, Lise, Chemtob, Sylvain, Michnick, Stephen W., Rioux, John D., Lesage, Sylvie

“…•Absence of IL-12Rβ2 protects from both induced and spontaneous colitis in IL10−/− mice.•The contribution of IL-23R deficiency to colitis development is…”
Get full text

Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response by Quiniou, Christiane, Domínguez-Punaro, Maria, Cloutier, Frank, Erfani, Atefeh, Ennaciri, Jamila, Sivanesan, Durgajini, Sanchez, Mélanie, Chognard, Gaëlle, Hou, Xin, Rivera, José Carlos, Beauchamp, Claudine, Charron, Guy, Vilquin, Marie, Kuchroo, Vijay, Michnick, Stephen, Rioux, John D, Lesage, Sylvie, Chemtob, Sylvain

“…IL-23 is part of the IL-12 family of cytokines and is composed of the p19 subunit specific to IL-23 and the p40 subunit shared with IL-12. IL-23 specifically…”
Get more information

Hijacking hepatitis C viral replication with a non-coding replicative RNA by Bitard, Juliette, Chognard, Gaëlle, Dumas, Estelle, Rumi, Julie, Masante, Cyril, Mahias, Kathleen, Astier-Gin, Thérèse, Ventura, Michel

“…The current treatments used against RNA viruses have a limited efficacy and are often hampered by the induction of side-effects. The specific delivery of…”
Get full text