Search Results - "Cho, Yoon Shin"

Codon usage trend in genes associated with obesity by Chakraborty, Supriyo, Barbhuiya, Parvin A., Paul, Sunanda, Uddin, Arif, Choudhury, Yashmin, Ahn, Yeongseon, Cho, Yoon Shin

“…Obesity is not only a social menace but also an economic burden as it reduces productivity and increases health care cost. We used bioinformatic tools to…”
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Understanding the functional role of genistein in the bone differentiation in mouse osteoblastic cell line MC3T3-E1 by RNA-seq analysis by Kim, Myungsuk, Lim, Jisun, Lee, Jung-Hee, Lee, Kyung-Mi, Kim, Suji, Park, Kye Won, Nho, Chu Won, Cho, Yoon Shin

“…Genistein, a phyto-estrogen, can potentially replace endogenous estrogens in postmenopausal women, but the underlying molecular mechanisms remain incompletely…”
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Hsa-miR-10a-5p downregulation in mutant UQCRB-expressing cells promotes the cholesterol biosynthesis pathway by Kim, Jeong Eun, Hong, Ji Won, Lee, Hannah S., Kim, Wankyu, Lim, Jisun, Cho, Yoon Shin, Kwon, Ho Jeong

“…Ubiquinol cytochrome c reductase binding protein (UQCRB) is known to play crucial roles in the development of various types of diseases. However, the link…”
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Large-scale genome-wide association study of Asian population reveals genetic factors in FRMD4A and other loci influencing smoking initiation and nicotine dependence by Yoon, Dankyu, Kim, Young-Jin, Cui, Wen-Yan, Van der Vaart, Andrew, Cho, Yoon Shin, Lee, Jong-Young, Ma, Jennie Z., Payne, Thomas J., Li, Ming D., Park, Taesung

“…Diseases related to smoking are the second leading cause of death in the world. Cigarette smoking is a risk factor for several diseases such as cancer and…”
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A Common Variant in SLC8A1 Is Associated with the Duration of the Electrocardiographic QT Interval by Kim, Jong Wook, Hong, Kyung-Won, Go, Min Jin, Kim, Sung Soo, Tabara, Yasuharu, Kita, Yoshikuni, Tanigawa, Takeshi, Cho, Yoon Shin, Han, Bok-Ghee, Oh, Bermseok

“…Prolongation of the electrocardiographic QT interval, a measure of cardiac repolarization, predisposes one to ventricular arrhythmias and sudden cardiac death…”
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Identification of 15 loci influencing height in a Korean population by Kim, Jae-Jung, Lee, Hae-In, Park, Taesung, Kim, Kyunga, Lee, Jong-Eun, Cho, Nam Han, Shin, Chol, Cho, Yoon Shin, Lee, Jong-Young, Han, Bok-Ghee, Yoo, Han-Wook, Lee, Jong-Keuk

“…Height is a complex genetic trait that involves multiple genetic loci. Recently, 44 loci associated with height were identified in Caucasian individuals by…”
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Development of a Polygenic Risk Score for BMI to Assess the Genetic Susceptibility to Obesity and Related Diseases in the Korean Population by Yoon, Nara, Cho, Yoon Shin

“…Hundreds of genetic variants for body mass index (BMI) have been identified from numerous genome-wide association studies (GWAS) in different ethnicities. In…”
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Identification of female-specific genetic variants for metabolic syndrome and its component traits to improve the prediction of metabolic syndrome in females by Kong, Sokanha, Cho, Yoon Shin

“…Metabolic syndrome (MetS), defined as a cluster of metabolic risk factors including dyslipidemia, insulin-resistance, and elevated blood pressure, has been…”
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Genotype instability during long-term subculture of lymphoblastoid cell lines by Oh, Ji Hee, Kim, Young Jin, Moon, Sanghoon, Nam, Hye-Young, Jeon, Jae-Pil, Lee, Jong Ho, Lee, Jong-Young, Cho, Yoon Shin

“…Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines (LCLs) promise to address the challenge posed by the limited availability of primary cells…”
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New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population by Go, Min Jin, Hwang, Joo-Yeon, Kim, Young Jin, Hee Oh, Ji, Kim, Yeon-Jung, Heon Kwak, Soo, Soo Park, Kyung, Lee, Juyoung, Kim, Bong-Jo, Han, Bok-Ghee, Cho, Myeong-Chan, Cho, Yoon Shin, Lee, Jong-Young

“…Most recently, 1-h hyperglycemia has been recognized as an additional risk factor for type 2 diabetes. To date, previous genome-wide association studies for…”
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Identification of shared genetic risks underlying metabolic syndrome and its related traits in the Korean population by Kim, Jun Young, Cho, Yoon Shin

“…Observational studies have demonstrated strong correlations between metabolic syndrome (MetS) and its related traits. To gain insight into the genetic…”
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Celastrol ameliorates cytokine toxicity and pro-inflammatory immune responses by suppressing NF-κB activation in RINm5F beta cells by Ju, Sung Mi, Youn, Gi Soo, Cho, Yoon Shin, Choi, Soo Young, Park, Jinseu

“…Upregulation of pro-inflammatory mediators contributes to ${\beta}$-cell destruction and enhanced infiltration of immune cells into pancreatic islets during…”
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Genetic association study identifies genetic variants for non-alcoholic fatty liver without comorbidities in the Korean population by Kim, Yeon Jun, Cho, Yoon Shin

“…Background Non-alcoholic fatty liver (NAFL) refers to a disease in which fat builds up in the liver, similar to what occurs for those who drink a lot of…”
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Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians by Kato, Norihiro, Takeuchi, Fumihiko, Tabara, Yasuharu, Kelly, Tanika N, Go, Min Jin, Sim, Xueling, Tay, Wan Ting, Chen, Chien-Hsiun, Zhang, Yi, Yamamoto, Ken, Katsuya, Tomohiro, Yokota, Mitsuhiro, Kim, Young Jin, Ong, Rick Twee Hee, Nabika, Toru, Gu, Dongfeng, Chang, Li-ching, Kokubo, Yoshihiro, Huang, Wei, Ohnaka, Keizo, Yamori, Yukio, Nakashima, Eitaro, Jaquish, Cashell E, Lee, Jong-Young, Seielstad, Mark, Isono, Masato, Hixson, James E, Chen, Yuan-Tsong, Miki, Tetsuro, Zhou, Xueya, Sugiyama, Takao, Jeon, Jae-Pil, Liu, Jian Jun, Takayanagi, Ryoichi, Kim, Sung Soo, Aung, Tin, Sung, Yun Ju, Zhang, Xuegong, Wong, Tien Yin, Han, Bok-Ghee, Kobayashi, Shotai, Ogihara, Toshio, Zhu, Dingliang, Iwai, Naoharu, Wu, Jer-Yuarn, Teo, Yik Ying, Tai, E Shyong, Cho, Yoon Shin, He, Jiang

“…Norihiro Kato and colleagues perform a meta-analysis of genome-wide association studies to identify common variants associated with blood pressure variation in…”
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A Genome-Wide Association Study of Gestational Diabetes Mellitus in Korean Women by SOO HEON KWAK, KIM, Sung-Hoon, CHO, Nam H, IN KYU LEE, SEONG YEON KIM, HAN, Bok-Ghee, JANG, Hak C, KYONG SOO PARK, YOUNG MIN CHO, MIN JIN GO, YOON SHIN CHO, SUNG HEE CHOI, MIN KYONG MOON, HYE SEUNG JUNG, HYOUNG DOO SHIN, HYUN MIN KANG

“…Knowledge regarding the genetic risk loci for gestational diabetes mellitus (GDM) is still limited. In this study, we performed a two-stage genome-wide…”
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Genome-wide association study identified new susceptibility loci for polycystic ovary syndrome by Lee, Hyejin, Oh, Jee-Young, Sung, Yeon-Ah, Chung, Hyewon, Kim, Hyung-Lae, Kim, Gwang Sub, Cho, Yoon Shin, Kim, Jin Taek

“…STUDY QUESTION Are there any novel genetic markers of susceptibility to polycystic ovary syndrome (PCOS)? SUMMARY ANSWER We identified a novel susceptibility…”
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A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits by Cho, Eun Young, Lee, Mi Hee, Park, Man Suk, Han, Bok-Ghee, Clarke, Geraldine, Oh, Bermseok, Cho, Yoon Shin, Go, Min Jin, Kim, Dong-Joon, Ahn, Younjhin, Shin, Chol, McCarthy, Mark I, Jang, Hye-Yoon, Lee, Jong-Koo, Cardon, Lon, Heo, Jee Yeon, Lee, Jong-Keuk, Oh, Ji Hee, Min, Haesook, Lee, Jong-Eun, Ban, Hyo-Jeong, Kim, Jun-Woo, Lee, Jong-Young, Kim, Young Jin, Kim, Hyung-Lae, Park, Ji Wan, Cha, Seung-Hun, Han, Hye Ree, Yoon, Dankyu, Park, Miey, Cho, Nam H, Park, Taesung

“…Hyung-Lae Kim and colleagues report a genome-wide association study of quantitative traits of biomedical importance in Koreans. Although some loci were…”
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The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians by Kim, Young Jin, Moon, Sanghoon, Hwang, Mi Yeong, Han, Sohee, Jang, Hye-Mi, Kong, Jinhwa, Shin, Dong Mun, Yoon, Kyungheon, Kim, Sung Min, Lee, Jong-Eun, Mahajan, Anubha, Park, Hyun-Young, McCarthy, Mark I., Cho, Yoon Shin, Kim, Bong-Jo

“…Metabolic traits are heritable phenotypes widely-used in assessing the risk of various diseases. We conduct a genome-wide association analysis (GWAS) of nine…”
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Large-scale genome-wide association studies in east Asians identify new genetic loci influencing metabolic traits by Cho, Yoon Shin, Kim, Young Jin, Go, Min Jin, Hu, Cheng, Hong, Chang Bum, Kim, Yun Kyoung, Lee, Ji Young, Hwang, Joo-Yeon, Oh, Ji Hee, Kim, Dong-Joon, Kim, Nam Hee, Kim, Soeui, Hong, Eun Jung, Kim, Ji-Hyun, Min, Haesook, Kim, Yeonjung, Zhang, Rong, Jia, Weiping, Okada, Yukinori, Takahashi, Atsushi, Kubo, Michiaki, Tanaka, Toshihiro, Kamatani, Naoyuki, Matsuda, Koichi, Park, Taesung, Oh, Bermseok, Kimm, Kuchan, Kang, Daehee, Shin, Chol, Cho, Nam H, Kim, Hyung-Lae, Han, Bok-Ghee, Lee, Jong-Young

“…To identify the genetic bases for nine metabolic traits, we conducted a meta-analysis combining Korean genome-wide association results from the KARE project (n…”
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Replication of the Wellcome Trust genome-wide association study on essential hypertension in a Korean population by Hong, Kyung-Won, Jin, Hyun-Seok, Cho, Yoon Shin, Lee, Jong-Young, Lee, Jong-Eun, Cho, Nam H, Shin, Chol, Lee, Sang-Ho, Park, Hun Kuk, Oh, Bermseok

“…Essential hypertension has a high rate of morbidity and mortality, primarily because of the associated complications. The Wellcome Trust Case Control…”
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