Search Results - "Cho, Steve K"

Characterization of Multiple Cytokine Combinations and TGF-β on Differentiation and Functions of Myeloid-Derived Suppressor Cells by Lee, Cho-Rong, Lee, Wongeun, Cho, Steve K, Park, Sung-Gyoo

“…Myeloid-derived suppressor cells (MDSCs) regulate T cell immunity, and this population is a new therapeutic target for immune regulation. A previous study…”
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Crbn modulates calcium influx by regulating Orai1 during efferocytosis by Moon, Hyunji, Min, Chanhyuk, Kim, Gayoung, Kim, Deokhwan, Kim, Kwanhyeong, Lee, Sang-Ah, Moon, Byeongjin, Yang, Susumin, Lee, Juyeon, Yang, Seung-Joo, Cho, Steve K., Lee, Gwangrog, Lee, Chang Sup, Park, Chul-Seung, Park, Daeho

“…Calcium flux regulating intracellular calcium levels is essential and modulated for efficient efferocytosis. However, the molecular mechanism by which calcium…”
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The Telomerase Antagonist, Imetelstat, Efficiently Targets Glioblastoma Tumor-Initiating Cells Leading to Decreased Proliferation and Tumor Growth by MARIAN, Calin O, CHO, Steve K, MCELLIN, Brian M, MAHER, Elizabeth A, HATANPAA, Kimmo J, MADDEN, Christopher J, MICKEY, Bruce E, WRIGHT, Woodring E, SHAY, Jerry W, BACHOO, Robert M

“…Purpose: Telomerase activity is one of the hallmarks of cancer and is a highly relevant therapeutic target. The effects of a novel human telomerase antagonist,…”
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Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma by Singh, Dinesh K., Kollipara, Rahul K., Vemireddy, Vamsidara, Yang, Xiao-Li, Sun, Yuxiao, Regmi, Nanda, Klingler, Stefan, Hatanpaa, Kimmo J., Raisanen, Jack, Cho, Steve K., Sirasanagandla, Shyam, Nannepaga, Suraj, Piccirillo, Sara, Mashimo, Tomoyuki, Wang, Shan, Humphries, Caroline G., Mickey, Bruce, Maher, Elizabeth A., Zheng, Hongwu, Kim, Ryung S., Kittler, Ralf, Bachoo, Robert M.

“…Efforts to identify and target glioblastoma (GBM) drivers have primarily focused on receptor tyrosine kinases (RTKs). Clinical benefits, however, have been…”
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Phosphorylation of p53 Serine 15 Is a Predictor of Survival for Patients with Hepatocellular Carcinoma by Kim, Dae-Shick, Cho, Steve K., Joh, Jae Won, Choi, Yegyun, Yang, Taewoo, Park, Sung-Gyoo

“…Background. Hepatocellular carcinoma (HCC) is one of the most common malignant cancers with a poor prognosis. Several commonly investigated immunohistochemical…”
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Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors by Marin-Valencia, Isaac, Cho, Steve K., Rakheja, Dinesh, Hatanpaa, Kimmo J., Kapur, Payal, Mashimo, Tomoyuki, Jindal, Ashish, Vemireddy, Vamsidhara, Good, Levi B., Raisanen, Jack, Sun, Xiankai, Mickey, Bruce, Choi, Changho, Takahashi, Masaya, Togao, Osamu, Pascual, Juan M., DeBerardinis, Ralph J., Maher, Elizabeth A., Malloy, Craig R., Bachoo, Robert M.

“…It has been hypothesized that increased flux through the pentose phosphate pathway (PPP) is required to support the metabolic demands of rapid malignant cell…”
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PKCθ-Mediated PDK1 Phosphorylation Enhances T Cell Activation by Increasing PDK1 Stability by Kang, Jung-Ah, Choi, Hyunwoo, Yang, Taewoo, Cho, Steve K, Park, Zee-Yong, Park, Sung-Gyoo

“…PDK1 is essential for T cell receptor (TCR)-mediated activation of $NF-{\kappa}B$, and PDK1-induced phosphorylation of $PKC{\theta}$ is important for…”
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Pheophorbide A and SN38 conjugated hyaluronan nanoparticles for photodynamic- and cascadic chemotherapy of cancer stem-like ovarian cancer by Lee, Junghan, Davaa, Enkhzaya, Jiang, Yixin, Shin, Kyung-Ju, Kim, Min Hye, An, Hyunsu, Kim, Jinho, Cho, Steve K., Yang, Su-Geun

“…In this study, we designed photo-triggered reactive oxygen species (ROS)-generating pheophorbide A and ROS-cleavable thioketal-SN38 conjugated…”
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Mitochondria-Targeting Peptoids by Nam, Ho Yeon, Hong, Jong-Ah, Choi, Jieun, Shin, Seungheon, Cho, Steve K, Seo, Jiwon, Lee, Jiyoun

“…Mitochondria-specific delivery methods offer a valuable tool for studying mitochondria-related diseases and provide breakthroughs in therapeutic development…”
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Surface-Immobilized Aptamers for Cancer Cell Isolation and Microscopic Cytology by YUAN WAN, KIM, Young-Tae, NA LI, CHO, Steve K, BACHOO, Robert, ELLINGTON, Andrew D, IQBAL, Samir M

“…Exposing rare but highly malignant tumor cells that migrate from the primary tumor mass into adjacent tissue(s) or circulate in the bloodstream is critical for…”
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Protective effect of TPP-Niacin on microgravity-induced oxidative stress and mitochondrial dysfunction of retinal epithelial cells by Nguyen, Hong Phuong, Shin, Seungheon, Shin, Kyung-Ju, Tran, Phuong Hoa, Park, Hyungsun, De Tran, Quang, No, Mi-Hyun, Sun, Ji Su, Kim, Ki Woo, Kwak, Hyo-Bum, Lee, Seongju, Cho, Steve K, Yang, Su-Geun

“…Adverse effects of spaceflight on the human body are attritubuted to microgravity and space radiation. One of the most sensitive organs affected by them is the…”
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A hydrazone-based turn-on fluorescent probe for peroxynitrite detection and live-cell imaging by Kim, Sudeok, Ko, Chang Woo, Lim, Taeho, Yoo, Soyeon, Ham, Hye Jin, Kang, Seo-Young, Kang, Seungyoon, Cho, Steve K., Han, Min Su

“…Peroxynitrite (ONOO−) plays an important physiological role and is related to various clinical diseases. In the past two decades, a number of fluorescent…”
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Ablation of CRBN induces loss of type I collagen and SCH in mouse skin by fibroblast senescence via the p38 MAPK pathway by Jeon, Seungje, Yoon, Yi-Seul, Kim, Hyoung Kyu, Han, Jin, Lee, Kwang Min, Seol, Jung Eun, Cho, Steve K, Park, Chul-Seung

“…Cereblon (CRBN) is a substrate receptor of the cullin-RING E3 ubiquitin ligase (CRL) complex that mediates the ubiquitination of several substrates. In this…”
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Identification and Characterization of a cDNA Encoding a Dolichyl Pyrophosphate Phosphatase Located in the Endoplasmic Reticulum of Mammalian Cells by Rush, Jeffrey S, Cho, Steve K, Jiang, Songmin, Hofmann, Sandra L, Waechter, Charles J

“…The CWH8 gene in Saccharomyces cerevisiae has been shown recently (Fernandez, F., Rush, J. S., Toke, D. A., Han, G., Quinn, J. E., Carman, G. M., Choi, J.-Y.,…”
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Ramalin, an antioxidant compound derived from Antarctic lichen, prevents progression of liver fibrosis induced by dimethylnitrosamine (DNM) in rats by Kim, Min-Kyoung, Kim, Min A., Yim, Joung Han, Lee, Don-Haeng, Cho, Steve K., Yang, Su-Geun

“…Hepatic fibrosis is characterized by the excessive accumulation of extracellular matrix (ECM), primarily collagen, within the liver. Because reactive oxygen…”
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Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells by Kwak, Seung-Hwa, Shin, Seungheon, Lee, Ji-Hyun, Shim, Jin-Kyoung, Kim, Minjeong, Lee, So-Deok, Lee, Aram, Bae, Jinsu, Park, Jin-Hee, Abdelrahman, Aliaa, Müller, Christa E., Cho, Steve K., Kang, Seok-Gu, Bae, Myung Ae, Yang, Jung Yoon, Ko, Hyojin, Goddard, William A., Kim, Yong-Chul

“…Screening a compound library of quinolinone derivatives identified compound 11a as a new P2X7 receptor antagonist. To optimize its activity, we assessed…”
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Comparative analysis of dermal collagen and lipids in cereblon ablated mice using a multimodal nonlinear optical system by Park, Chang Woo, Jeon, Seungje, Kwon, Seong‐Hoon, Jung, Jun‐Hyung, Seol, Jung Eun, Park, Chul‐Seung, Cho, Steve K., Ko, Do‐Kyeong

“…By utilizing a multimodal nonlinear optical system that combines coherent anti‐Stokes Raman scattering and second harmonic generation to investigate biological…”
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PKCθ-Mediated PDK1 Phosphorylation Enhances T Cell Activation by Increasing PDK1 Stability by Kang, Jung-Ah, Choi, Hyunwoo, Yang, Taewoo, Cho, Steve K, Park, Zee-Yong, Park, Sung-Gyoo

“…PDK1 is essential for T cell receptor (TCR)-mediated activation of NF-κB, and PDK1-induced phosphorylation of PKCθ is important for TCR-induced NF-κB…”
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pdf1, a Palmitoyl Protein Thioesterase 1 Ortholog in Schizosaccharomyces pombe: a Yeast Model of Infantile Batten Disease by Cho, Steve K, Hofmann, Sandra L

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Enhanced conjugation stability and blood circulation time of macromolecular gadolinium-DTPA contrast agent by Jenjob, Ratchapol, Kun, Na, Ghee, Jung Yeon, Shen, Zheyu, Wu, Xiaoxia, Cho, Steve K., Lee, Don Haeng, Yang, Su-Geun

“…In this study, we prepared macromolecular MR T1 contrast agent: pullulan-conjugated Gd diethylene triamine pentaacetate (Gd-DTPA-Pullulan) and estimated…”
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