Search Results - "Cho, Sarah K"

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death by Daugas, Eric, Elia, Andrew J, Joza, Nicholas, Stanford, William L, Kong, Young-Yun, Ravagnan, Luigi, Ferri, Karine F, Mak, Tak W, Zúñiga-Pflücker, Juan Carlos, Yoshida, Hiroki, Penninger, Josef M, Cheng, H.-Y. Mary, Cho, Sarah K, Li, Carol Y. J, Zamzami, Naoufal, Susin, Santos A, Wakeham, Andrew, Sasaki, Takehiko, Kroemer, Guido, Hakem, Razqallah

“…Programmed cell death is a fundamental requirement for embryogenesis, organ metamorphosis and tissue homeostasis. In mammals, release of mitochondrial…”
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Assessment of Plasma DNA Levels, Allelic Imbalance, and CA 125 as Diagnostic Tests for Cancer by Chang, Hsueh-Wei, Lee, Shing M., Goodman, Steven N., Singer, Gad, Cho, Sarah K. R., Sokoll, Lori J., Montz, Fredrick J., Roden, Richard, Zhang, Zhen, Chan, Daniel W., Kurman, Robert J., Shih, Ie-Ming

“…Background: Allelic imbalance (AI), the loss or gain of chromosomal regions, is found in many cancers. AI can be detected in genomic tumor DNA released into…”
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Expression and function of CD105 during the onset of hematopoiesis from Flk1+ precursors by Cho, Sarah K., Bourdeau, Annie, Letarte, Michelle, Zúñiga-Pflücker, Juan Carlos

“…During ontogeny, the hematopoietic system is established from mesoderm-derived precursors; however, molecular events regulating the onset of hematopoiesis are…”
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Functional Characterization of B Lymphocytes Generated in vitro from Embryonic Stem Cells by Cho, Sarah K., Webber, Travis D., Carlyle, James R., Nakano, Toru, Lewis, Susanna M., Zúñiga-Pflücker, Juan Carlos

“…To study molecular events involved in B lymphocyte development and V(D)J rearrangement, we have established an efficient system for the differentiation of…”
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Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro by de Pooter, Renée F, Cho, Sarah K, Gronski, Matthew A, Schmitt, Thomas M, Ohashi, Pamela S, Zúñiga-Pflücker, Juan Carlos

“…Embryonic stem cells (ESCs) have the potential to serve as a renewable source of transplantable tissue-specific stem cells. However, the molecular cues…”
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Diverse Tumorigenic Pathways in Ovarian Serous Carcinoma by Singer, Gad, Kurman, Robert J., Chang, Hsueh-Wei, Cho, Sarah K.R., Shih, Ie-Ming

“…This study was undertaken to analyze genetic alterations in 108 sporadic serous ovarian neoplasms to elucidate ovarian serous carcinogenesis. Our results…”
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Detection of Allelic Imbalance in Ascitic Supernatant by Digital Single Nucleotide Polymorphism Analysis by CHANG, Hsueh-Wei, ALI, Syed Z, CHO, Sarah K. R, KURMAN, Robert J, SHIH, Ie-Ming

“…Purpose: Cytological examination of ascitic fluid is critical for clinical management of patients with peritoneal or pelvic diseases. Such morphological…”
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In vitro generation of T lymphocytes from embryonic stem cell–derived prehematopoietic progenitors by de Pooter, Renée F., Cho, Sarah K., Carlyle, James R., Zúñiga-Pflücker, Juan Carlos

“…Embryonic stem (ES) cells can differentiate into most blood cells in vitro, providing a powerful model system to study hematopoiesis. However, ES cell–derived…”
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In vitro generation of lymphocytes from embryonic stem cells by de Pooter, Renée F, Cho, Sarah K, Zúñiga-Pflücker, Juan Carlos

“…Lymphocytes arise during ontogeny via a series of increasingly restricted intermediates. Initially, the mesoderm gives rise to hemangioblasts, which can…”
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Clonal Characterization of a Bipotent T Cell and NK Cell Progenitor in the Mouse Fetal Thymus by Michie, Alison M, Carlyle, James R, Schmitt, Thomas M, Ljutic, Belma, Cho, Sarah K, Fong, Quyen, Zuniga-Pflucker, Juan Carlos

“…We recently described a population of fetal thymocytes with a CD117+NK1.1+CD90lowCD25- phenotype, which were shown to contain committed T cell and NK cell…”
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Development of lymphoid lineages from embryonic stem cells in vitro by Cho, Sarah K, Zúñiga-Pflücker, Juan Carlos

“…Lymphocyte development proceeds through highly ordered and regulated stages, as multipotent hematopoietic progenitors differentiate into lineage-defined…”
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The stress kinase mitogen-activated protein kinase kinase (MKK)7 is a negative regulator of antigen receptor and growth factor receptor-induced proliferation in hematopoietic cells by Sasaki, T, Wada, T, Kishimoto, H, Irie-Sasaki, J, Matsumoto, G, Goto, T, Yao, Z, Wakeham, A, Mak, T W, Suzuki, A, Cho, S K, Zuniga-Pflucker, J C, Oliveira-dos-Santos, A J, Katada, T, Nishina, H, Penninger, J M

“…The dual specificity kinases mitogen-activated protein kinase (MAPK) kinase (MKK)7 and MKK4 are the only molecules known to directly activate the stress…”
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Coordination of Repair, Checkpoint, and Cell Death Responses to DNA Damage by Wang, Jean Y.J., Cho, Sarah K.

“…This chapter describes a variety of DNA repair mechanisms for the self-preservation and self-protection of cells. Continual DNA damage that occurs from…”
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Natural Killer Cell Development and Function Precede αβ T Cell Differentiation in Mouse Fetal Thymic Ontogeny by Carlyle, James R., Michie, Alison M., Cho, Sarah K., Zúñiga-Pflücker, Juan Carlos

“…Natural killer (NK) cells mediate MHC-unrestricted cytolysis of virus-infected cells and tumor cells. In the adult mouse, NK cells are bone marrow-derived…”
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Natural Killer Cell Development and Function Precede {alpha}{beta} T Cell Differentiation in Mouse Fetal Thymic Ontogeny by Carlyle, James R, Michie, Alison M, Cho, Sarah K, Zuniga-Pflucker, Juan Carlos

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