Search Results - "Cho, Kae‐Won"
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The IKK‐related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists
Published in The EMBO journal (04-01-2018)“…The innate immune kinase TBK1 initiates inflammatory responses to combat infectious pathogens by driving production of type I interferons. TBK1 also controls…”
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2
An MHC II-Dependent Activation Loop between Adipose Tissue Macrophages and CD4+ T Cells Controls Obesity-Induced Inflammation
Published in Cell reports (Cambridge) (23-10-2014)“…An adaptive immune response triggered by obesity is characterized by the activation of adipose tissue CD4+ T cells by unclear mechanisms. We have examined…”
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Adipose Tissue Dendritic Cells: Critical Regulators of Obesity-Induced Inflammation and Insulin Resistance
Published in International journal of molecular sciences (12-08-2021)“…Chronic inflammation of the adipose tissue (AT) is a critical component of obesity-induced insulin resistance and type 2 diabetes. Adipose tissue immune cells,…”
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4
Genetic Variations Leading to Familial Dilated Cardiomyopathy
Published in Molecules and cells (2016)“…Cardiomyopathy is a major cause of death worldwide. Based on pathohistological abnormalities and clinical manifestation, cardiomyopathies are categorized into…”
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5
Telmisartan increases hepatic glucose production via protein kinase C ζ-dependent insulin receptor substrate-1 phosphorylation in HepG2 cells and mouse liver
Published in Yeungnam University Journal of Medicine (2019)“…Background: Dysregulation of hepatic glucose production (HGP) contributes to the development of type 2 diabetes mellitus. Telmisartan, an angiotensin II type 1…”
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6
Metabolism and function of polyamines in cancer progression
Published in Cancer letters (28-10-2021)“…Polyamines are essential for the proliferation, differentiation, and development of eukaryotes. They include spermine, spermidine, and the diamine precursor…”
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Adipose Tissue Macrophages Function As Antigen-Presenting Cells and Regulate Adipose Tissue CD4+ T Cells in Mice
Published in Diabetes (New York, N.Y.) (01-08-2013)“…The proinflammatory activation of leukocytes in adipose tissue contributes to metabolic disease. How crosstalk between immune cells initiates and sustains…”
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Macrophage Proliferation Sustains Adipose Tissue Inflammation in Formerly Obese Mice
Published in Diabetes (New York, N.Y.) (01-02-2017)“…Obesity causes dramatic proinflammatory changes in the adipose tissue immune environment, but relatively little is known regarding how this inflammation…”
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Adipose Tissue Dendritic Cells Are Independent Contributors to Obesity-Induced Inflammation and Insulin Resistance
Published in The Journal of immunology (1950) (01-11-2016)“…Dynamic changes of adipose tissue leukocytes, including adipose tissue macrophage (ATM) and adipose tissue dendritic cells (ATDCs), contribute to…”
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10
Differences in Hematopoietic Stem Cells Contribute to Sexually Dimorphic Inflammatory Responses to High Fat Diet-induced Obesity
Published in The Journal of biological chemistry (22-05-2015)“…Women of reproductive age are protected from metabolic disease relative to postmenopausal women and men. Most preclinical rodent studies are skewed toward the…”
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Obese visceral adipose dendritic cells downregulate regulatory T cell development through IL-33
Published in Frontiers in immunology (19-03-2024)“…Regulatory T cells (Tregs) residing in visceral adipose tissue (VAT) play a pivotal role in regulating tissue inflammation and metabolic dysfunction associated…”
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Neuropeptide Y is produced by adipose tissue macrophages and regulates obesity-induced inflammation
Published in PloS one (05-03-2013)“…Neuropeptide Y (NPY) is induced in peripheral tissues such as adipose tissue with obesity. The mechanism and function of NPY induction in fat are unclear…”
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13
Genetic Variations Leading to Familial Dilated Cardiomyopathy
Published in Molecules and cells (01-10-2016)“…Cardiomyopathy is a major cause of death worldwide. Based on pathohistological abnormalities and clinical manifestation, cardiomyopathies are categorized into…”
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14
Dietary naringenin increases hepatic peroxisome proliferators–activated receptor α protein expression and decreases plasma triglyceride and adiposity in rats
Published in European journal of nutrition (01-03-2011)“…Background Naringenin, a flavonoid present in grapefruit, has recently been shown to exert hypolipidemic and hypocholesterolemic effects, which has a…”
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15
Mechanical Stress Improves Fat Graft Survival by Promoting Adipose-Derived Stem Cells Proliferation
Published in International journal of molecular sciences (01-10-2022)“…Cell-assisted lipotransfer (CAL), defined as co-transplantation of aspirated fat with enrichment of adipose-derived stem cells (ASCs), is a novel technique for…”
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Dynamic Roles and Expanding Diversity of Adipose Tissue Macrophages in Obesity
Published in Journal of Obesity & Metabolic Syndrome (30-09-2024)“…Adipose tissue macrophages (ATMs) are key regulators of adipose tissue (AT) inflammation and insulin resistance in obesity, and the traditional M1/M2…”
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SH2B1 Enhances Insulin Sensitivity by Both Stimulating the Insulin Receptor and Inhibiting Tyrosine Dephosphorylation of Insulin Receptor Substrate Proteins
Published in Diabetes (New York, N.Y.) (01-09-2009)“…SH2B1 Enhances Insulin Sensitivity by Both Stimulating the Insulin Receptor and Inhibiting Tyrosine Dephosphorylation of Insulin Receptor Substrate Proteins…”
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Ginsenoside Rd ameliorates muscle wasting by suppressing the signal transducer and activator of transcription 3 pathway
Published in Journal of cachexia, sarcopenia and muscle (01-12-2022)“…Background The effects of some drugs, aging, cancers, and other diseases can cause muscle wasting. Currently, there are no effective drugs for treating muscle…”
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Lipocalin-13 Regulates Glucose Metabolism by both Insulin-Dependent and Insulin-Independent Mechanisms
Published in Molecular and Cellular Biology (01-02-2011)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Macrophage Lamin A/C Regulates Inflammation and the Development of Obesity-Induced Insulin Resistance
Published in Frontiers in immunology (20-04-2018)“…Obesity-induced chronic low-grade inflammation, in particular in adipose tissue, contributes to the development of insulin resistance and type 2 diabetes…”
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