Search Results - "Cho, Ha Yeon"
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O2- and NO-Sensing Mechanism through the DevSR Two-Component System in Mycobacterium smegmatis
Published in Journal of Bacteriology (01-10-2008)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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2
Exploration of a new consumer test method based on metacognitive certainty
Published in Food quality and preference (01-04-2020)“…•A new consumer test method, the metacognitive authenticity test, was designed.•It included the metacognitive certainty response following sensory authenticity…”
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3
Structural Insight into the Heme-based Redox Sensing by DosS from Mycobacterium tuberculosis
Published in The Journal of biological chemistry (08-05-2009)“…Mycobacterium tuberculosis is thought to undergo transformation into its non-replicating persistence state under the influence of hypoxia or nitric oxide (NO)…”
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4
Optimal difference test sequence and power for discriminating soups of varying sodium content: DTFM version of dual-reference duo–trio with unspecified tetrad tests
Published in Food research international (01-10-2015)“…As sodium reduction has become very important in the food industry, various types of unspecified duo–trio tests have been studied to improve its efficiency for…”
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5
Structural basis for the dynamics of human methionyl-tRNA synthetase in multi-tRNA synthetase complexes
Published in Nucleic acids research (21-06-2021)“…Abstract In mammals, eight aminoacyl-tRNA synthetases (AARSs) and three AARS-interacting multifunctional proteins (AIMPs) form a multi-tRNA synthetase complex…”
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6
Symmetric Assembly of a Decameric Subcomplex in Human Multi-tRNA Synthetase Complex Via Interactions between Glutathione Transferase-Homology Domains and Aspartyl-tRNA Synthetase
Published in Journal of molecular biology (08-11-2019)“…Aminoacyl-tRNA synthetases (AARSs) ligate amino acids to their cognate tRNAs during protein synthesis. In humans, eight AARSs and three non-enzymatic…”
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7
The Effect of an Infant’s Mother’s Parenting Stress and Her Perception of Father’s Parenting Participation on Parent Role Satisfaction
Published in Korean Journal of child studies (01-08-2022)“…Objectives: This study investigates the effect of parenting stress on mothers of infants and the participation of fathers in raising the infants as perceived…”
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X‑ray Crystal Structure-Guided Design and Optimization of 7H‑Pyrrolo[2,3‑d]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor
Published in Journal of medicinal chemistry (27-05-2021)“…Triple-negative breast cancer (TNBC) is an aggressive breast-cancer subtype associated with poor prognosis and high relapse rates. Monopolar spindle 1 kinase…”
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9
Serine 83 in DosR, a response regulator from Mycobacterium tuberculosis, promotes its transition from an activated, phosphorylated state to an inactive, unphosphorylated state
Published in Biochemical and biophysical research communications (21-02-2014)“…•DosR and NarL from Mycobacterium tuberculosis belong to the same subgroup.•The histidine kinase DosS phosphorylates not only DosR but also…”
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X-ray Crystal Structure-Guided Design and Optimization of 7 H -Pyrrolo[2,3- d ]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor
Published in Journal of medicinal chemistry (27-05-2021)“…Triple-negative breast cancer (TNBC) is an aggressive breast-cancer subtype associated with poor prognosis and high relapse rates. Monopolar spindle 1 kinase…”
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11
Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2
Published in Cancer research (Chicago, Ill.) (01-06-2016)“…AIMP2/p38 is a multifunctional tumor suppressor that normally resides in the cytosol as a scaffold protein of the multi-tRNA synthetase complex (MSC). One of…”
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12
Assembly of Multi-tRNA Synthetase Complex via Heterotetrameric Glutathione Transferase-homology Domains
Published in The Journal of biological chemistry (04-12-2015)“…Many multicomponent protein complexes mediating diverse cellular processes are assembled through scaffolds with specialized protein interaction modules. The…”
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13
NADP+-dependent cytosolic isocitrate dehydrogenase provides NADPH in the presence of cadmium due to the moderate chelating effect of glutathione
Published in Journal of biological inorganic chemistry (01-08-2018)“…Cadmium (Cd 2+ ) is toxic to living organisms because it causes the malfunction of essential proteins and induces oxidative stress. NADP + -dependent cytosolic…”
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14
Structural basis for substrate binding to human pyridoxal 5′-phosphate phosphatase/chronophin by a conformational change
Published in International journal of biological macromolecules (15-06-2019)“…Human pyridoxal 5′-phosphate phosphatase (PLPP), also known as a chronophin, is a phosphatase belonging to subfamily II of the HAD phosphatases, characterized…”
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15
Activation of ATP Binding for the Autophosphorylation of DosS, a Mycobacterium tuberculosis Histidine Kinase Lacking an ATP Lid Motif
Published in The Journal of biological chemistry (03-05-2013)“…The sensor histidine kinases of Mycobacterium tuberculosis, DosS and DosT, are responsible for sensing hypoxic conditions and consist of sensor and kinase…”
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16
Structural and functional analysis of bacterial flavin-containing monooxygenase reveals its ping-pong-type reaction mechanism
Published in Journal of structural biology (01-07-2011)“…A bacterial flavin-containing monooxygenase (bFMO) catalyses the oxygenation of indole to produce indigoid compounds. In the reductive half of the indole…”
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17
Blockage of the channel to heme by the E87 side chain in the GAF domain of Mycobacterium tuberculosis DosS confers the unique sensitivity of DosS to oxygen
Published in FEBS letters (23-06-2011)“…► A channel to the heme in DosS can be blocked by E87. ► DosT has an open channel to heme due to G85. ► DosS mutants with an open channel bind oxygen when they…”
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Abstract P1-11-03: VRN101099, Brain Permeable HER2 Kinase Inhibitor, Shows the Anti-tumor Activity in Preclinical Models of HER2-positive Cancers
Published in Cancer research (Chicago, Ill.) (01-03-2023)“…The brain is a common target organ for breast cancer metastasis, and the risk of brain metastasis is usually high for patients with HER2-positive breast…”
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Abstract LB521: Antitumor activity of potent RAF inhibitors in solid tumors with activated RAS-RAF axis
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…FDA approved three RAF inhibitors for the treatment of tumors containing BRAFV600 mutations, but one of the major drawbacks of these type I RAF inhibitors is…”
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20
Substrate Binding Mechanism of a Type I Extradiol Dioxygenase
Published in The Journal of biological chemistry (05-11-2010)“…A meta-cleavage pathway for the aerobic degradation of aromatic hydrocarbons is catalyzed by extradiol dioxygenases via a two-step mechanism: catechol…”
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