Search Results - "Cho, Doo‐Wan"
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KDS2010, a Newly Developed Reversible MAO-B Inhibitor, as an Effective Therapeutic Candidate for Parkinson’s Disease
Published in Neurotherapeutics (01-07-2021)“…Monoamine oxidase-B (MAO-B) is a well-established therapeutic target for Parkinson’s disease (PD); however, previous clinical studies on currently available…”
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Repeated injection of KMRC011, a medical countermeasure for radiation, can cause adverse health effects in cynomolgus monkeys
Published in Journal of applied toxicology (01-02-2019)“…High‐dose radiation‐induced tissue damage is a major limiting factor in the medical application of nuclear technology. Herein, we tested 28‐day repeated‐dose…”
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SYNCRIP controls miR-137 and striatal learning in animal models of methamphetamine abstinence
Published in Acta pharmaceutica Sinica. B (01-08-2022)“…Abstinence from prolonged psychostimulant use prompts stimulant withdrawal syndrome. Molecular adaptations within the dorsal striatum have been considered the…”
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Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study
Published in Laboratory animal research (16-10-2021)“…BACKGROUNDTelemetry is a wireless implanted device that measures biological signals in conscious animals and usually requires surgery for its removal when the…”
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KMRC011, an agonist of toll-like receptor 5, mitigates irradiation-induced tissue damage and mortality in cynomolgus monkeys
Published in Journal of immunotoxicology (01-01-2020)“…In the study here, the potential applicability of KMRC011 - an agonist of toll-like receptor-5 - as a countermeasure for radiation toxicities was evaluated…”
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Differential Cellular Tropism of Lentivirus and Adeno-Associated Virus in the Brain of Cynomolgus Monkey
Published in Experimental neurobiology (01-02-2016)“…Many researchers are using viruses to deliver genes of interest into the brains of laboratory animals. However, certain target brain cells are not easily…”
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Claustral MeCP2 Regulates Methamphetamine-induced Conditioned Place Preference in Cynomolgus Monkey
Published in Experimental neurobiology (31-12-2022)“…The claustrum, a brain nucleus located between the cortex and the striatum, has recently been highlighted in drug-related reward processing. Methyl CpG-binding…”
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Four-week repeated dose oral toxicity study of KDS2010, a novel selective monoamine oxidase B inhibitor, in Sprague Dawley rats
Published in Regulatory toxicology and pharmacology (01-11-2020)“…Repeated dose oral toxicity and toxicokinetic of KDS2010, a new drug for Parkinson's disease, was investigated after 4-week repeated oral administration at 30,…”
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Thirteen-week oral toxicity study of fermented ginseng, GBCK25, in Sprague-Dawley rats
Published in Regulatory toxicology and pharmacology (01-12-2020)“…Ginseng (Panax ginseng) is commonly used in Asia as a medicinal herb. In particular, fermented ginseng, GBCK25, has been recently developed to increase…”
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Two weeks dose range-finding and four weeks repeated dose oral toxicity study of a novel reversible monoamine oxidase B inhibitor KDS2010 in cynomolgus monkeys
Published in Toxicological research (Seoul) (01-10-2023)“…A novel reversible monoamine oxidase B inhibitor, KDS2010, has been developed as a therapeutic candidate for neurodegenerative diseases. This study…”
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Procedure to prevent epidemic disease for nonhuman primate during quarantine periods
Published in Toxicology letters (20-10-2017)Get full text
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Differential Cellular Tropism of Lentivirus and Adeno-Associated Virus in the Brain of Cynomolgus Monkey
Published in Experimental neurobiology (30-06-2021)Get full text
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Transdifferentiation of reactive astrocytes into functional neurons causes motor recovery after spinal cord injury
Published in IBRO reports (01-09-2019)Get full text
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Numerical Analysis of the Adhesive Forces in Nano-Scale Structure
Published in Journal of bionics engineering (01-12-2006)“…Nanohairs, which can be found on the epidermis of Tokay gecko's toes, contribute to the adhesion by means of van der Waals force, capillary force, etc. This…”
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