Search Results - "Cho, Aaron"
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Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity
Published in Nature communications (02-12-2022)“…Recent studies have shown that G protein coupled receptors (GPCRs) show selective and promiscuous coupling to different Gα protein subfamilies and yet the…”
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Utility of susceptibility weighted imaging (SWI) and pseudo-continuous arterial spin labeling (pCASL) in diagnosis of falcine venous thrombosis in a child with transient ischemic attack
Published in Emergency radiology (01-06-2021)“…Pediatric stroke and transient ischemic attack (TIA) are uncommon but true emergencies with a wide differential diagnosis. Diagnostic imaging plays a critical…”
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3
Cervical Spine Fracture With Vertebral Artery Dissection
Published in The journal of orthopaedic and sports physical therapy (01-10-2016)“…A 51-year-old man presented to a direct-access physical therapy clinic with persistent neck pain for 5 days after a fall in shallow water while surfing. Based…”
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4
Magnetic resonance imaging of uveitis
Published in Neuroradiology (01-08-2015)“…Introduction Uveitis is a term used to describe inflammation of the choroid, iris, or ciliary body, which make up the uveal tract. It can be idiopathic or…”
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Endovascular embolization of complex hypervascular skull base tumors
Published in Operative techniques in otolaryngology--head and neck surgery (01-03-2014)“…Neurointerventional radiology plays a critical role in the endovascular evaluation and treatment of complex hypervascular skull base tumors. In this article,…”
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Elucidating Functional Selectivity at the Prostaglandin F Receptor
Published 01-01-2022“…The prostaglandin F (FP) receptor plays an important role in parturition and is a potential target for delaying preterm birth. In myometrial cells, its natural…”
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Dissertation -
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Angiotensin II type 1 receptor variants alter endosomal receptor–β-arrestin complex stability and MAPK activation
Published in The Journal of biological chemistry (18-09-2020)“…The angiotensin II (AngII) type 1 receptor (AT1R), a member of the G protein–coupled receptor (GPCR) family, signals through G proteins and β-arrestins, which…”
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Prostaglandin F2α and angiotensin II type 1 receptors exhibit differential cognate G protein coupling regulation
Published in The Journal of biological chemistry (01-09-2022)“…Promiscuous G protein–coupled receptors (GPCRs) engage multiple Gα subtypes with different efficacies to propagate signals in cells. A mechanistic…”
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Not Just Down and Out: Oculomotor Nerve Pathologic Spectrum
Published in Current problems in diagnostic radiology (01-03-2022)“…The purpose of this article is to understand the complex pathologic spectrum of oculomotor nerve palsy. We review the detailed anatomy and function of the…”
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10
Unraveling allostery within the angiotensin II type 1 receptor for Gα q and β-arrestin coupling
Published in Science signaling (08-08-2023)“…G protein-coupled receptors engage both G proteins and β-arrestins, and their coupling can be biased by ligands and mutations. Here, to resolve structural…”
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Genetic code expansion and photocross-linking identify different β-arrestin binding modes to the angiotensin II type 1 receptor
Published in The Journal of biological chemistry (15-11-2019)“…The angiotensin II (AngII) type 1 receptor (AT1R) is a member of the G protein–coupled receptor (GPCR) family and binds β-arrestins (β-arrs), which regulate…”
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Large saccular intracranial aneurysm in a child with RASA1-associated capillary malformation–arteriovenous malformation syndrome: illustrative case
Published in Journal of neurosurgery. Case lessons (28-08-2023)“…BACKGROUND Large cerebral aneurysms are much less common in children than in adults. Thus, when present, these lesions require careful surgical evaluation and…”
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Multinodular and vacuolating neuronal tumor: Case report of a rare pathologic diagnosis
Published in Interdisciplinary neurosurgery : Advanced techniques and case management (01-03-2020)“…•MVNT is a rare lesion associated with seizure activity.•Imaging and clinical follow up suggest MVNT exhibits indolent behavior.•Adjuvant therapy for MVNT may…”
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An early venous abnormality: a potential cause of arteriovenous malformation recurrence
Published in BMJ case reports (11-09-2012)“…In adults, complete surgical resection of arteriovenous malformations (AVMs) is generally curative. Recurrence of AVMs is extremely rare and most often delayed…”
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An early venous abnormality: a potential cause of arteriovenous malformation recurrence
Published in BMJ Case Reports (2012)“…In adults, complete surgical resection of arteriovenous malformations (AVMs) is generally curative. Recurrence of AVMs is extremely rare and most often delayed…”
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Visually triggered migraine headaches affect spatial orientation and balance in a helicopter pilot
Published in Aviation, space, and environmental medicine (01-04-1995)“…The authors present a case of an attack helicopter pilot with recurrent spatial disorientation (SD) flying with night vision goggles (NVG's), diagnosed as…”
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