Search Results - "Chmielewski, David"
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1
Structural insights into the modulation of coronavirus spike tilting and infectivity by hinge glycans
Published in Nature communications (07-11-2023)“…Coronavirus spike glycoproteins presented on the virion surface mediate receptor binding, and membrane fusion during virus entry and constitute the primary…”
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Journal Article -
2
Alphavirus Particles Can Assemble with an Alternate Triangulation Number
Published in Viruses (27-11-2022)“…Alphaviruses are spherical, enveloped RNA viruses primarily transmitted by mosquitoes, and cause significant arthritogenic and neurotropic disease in humans…”
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3
Isolation and characterization of kidney-derived stem cells
Published in Journal of the American Society of Nephrology (01-11-2006)“…Acute kidney injury is followed by regeneration of damaged renal tubular epithelial cells. The purpose of this study was to test the hypothesis that renal stem…”
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4
The Candida albicans ESCRT Pathway Makes Rim101-Dependent and -Independent Contributions to Pathogenesis
Published in Eukaryotic Cell (01-08-2010)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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5
A role for extrarenal cells in the regeneration following acute renal failure
Published in Kidney international (01-10-2002)“…A role for extrarenal cells in the regeneration following acute renal failure. Recovery of renal function following acute tubular necrosis (ATN) is dependent…”
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6
A 3.4-Å cryo-electron microscopy structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles
Published in QRB discovery (17-11-2020)“…Human coronavirus NL63 (HCoV-NL63) is an enveloped pathogen of the family that spreads worldwide and causes up to 10% of all annual respiratory diseases…”
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7
Apolipoprotein J/Clusterin Prevents a Progressive Glomerulopathy of Aging
Published in Molecular and Cellular Biology (01-03-2002)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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8
Structure-Based Studies of RNA Virus Entry and Assembly in the Native Context
Published 01-01-2022“…Electron cryomicroscopy (cryo-EM) has rapidly become the method of choice for structural studies of macromolecular complexes in vitro, but often comes at the…”
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Dissertation -
9
Chikungunya virus assembly and budding visualized in situ using cryogenic electron tomography
Published in Nature microbiology (01-08-2022)“…Chikungunya virus (CHIKV) is a representative alphavirus causing debilitating arthritogenic disease in humans. Alphavirus particles assemble into two…”
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10
Molecular architecture of the Chikungunya virus replication complex
Published in Science advances (02-12-2022)“…To better understand how positive-strand (+) RNA viruses assemble membrane-associated replication complexes (RCs) to synthesize, process, and transport viral…”
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Journal Article -
11
Oligomerization of DDR1 ECD affects receptor-ligand binding
Published in Journal of structural biology (01-09-2013)“…Discoidin domain receptor 1 (DDR1) is a widely expressed receptor tyrosine kinase (RTK) which regulates cell differentiation, proliferation and migration and…”
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12
Cryogenic electron microscopy and tomography reveal imperfect icosahedral symmetry in alphaviruses
Published in PNAS nexus (01-03-2024)“…Alphaviruses are spherical, enveloped RNA viruses with two-layered icosahedral architecture. The structures of many alphaviruses have been studied using…”
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Journal Article -
13
Clusterin promotes the aggregation and adhesion of renal porcine epithelial cells
Published in The Journal of clinical investigation (01-12-1995)“…The function of clusterin, a heterodimeric glycoprotein markedly induced in renal and other organ injuries, is unclear. Since renal injury is accompanied by…”
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Journal Article -
14
Induction of clusterin in tubules of nephrotic rats
Published in Journal of the American Society of Nephrology (1998)“…Clusterin is a glycoprotein induced after renal tubular cell injury. The purpose of this study was to examine the expression of clusterin in a disease model…”
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15
Effect of dietary protein on rat renin and angiotensinogen gene expression
Published in The Journal of clinical investigation (01-04-1990)“…Plasma renin activity varies with the level of dietary protein, being higher on a high protein diet. To explore the molecular mechanisms underlying this…”
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Effect of angiotensin II and norepinephrine on early growth response genes in the rat kidney
Published in Kidney international (01-03-1993)“…Effect of angiotensin II and norepinephrine on early growth response genes in the rat kidney. Angiotensin II (Ang II) has growth promoting effects in a number…”
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Journal Article Conference Proceeding -
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HOME SCHOOLING: AN EDUCATIONAL OPTION
Published 01-01-1987“…This study explores the legal guidelines and state regulations concerning the viability of home schooling as an educational alternative. Currently, laws…”
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Dissertation -
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A distributed platform for archiving and retrieving RSS feeds
Published in Fourth Annual ACIS International Conference on Computer and Information Science (ICIS'05) (2005)“…A typical user has a collection of Web sites she often visits to get information, but keeping track of "what's new" on these Web sites is a nontrivial task. As…”
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Conference Proceeding -
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Relationship between renin, angiotensinogen and histone H2b messenger ribonucleic acid in the maturing rat kidney
Published in Nephron (2015) (1992)“…Postnatal nephrogenesis and growth of the rat kidney is greatest during the first 10 days of life. The renin-angiotensin system has important growth-promoting…”
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Journal Article -
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Temporal induction of clusterin in the peri-infarct zone after experimental myocardial infarction in the rat
Published in The Journal of laboratory and clinical medicine (1998)“…Clusterin, a glycoprotein with potent cellular cohesive properties, is induced in many organs at times of tissue injury or remodeling. After renal infarction,…”
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Journal Article