Search Results - "Chivukula, IV"
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Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination
Published in Nature communications (07-08-2020)“…Many important cell types in adult vertebrates have a mesenchymal origin, including fibroblasts and vascular mural cells. Although their biological importance…”
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Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations
Published in Gastroenterology (New York, N.Y. 1943) (01-03-2018)“…Alagille syndrome is a genetic disorder characterized by cholestasis, ocular abnormalities, characteristic facial features, heart defects, and vertebral…”
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Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKb
Published in Oncogene (10-10-2013)Get full text
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Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ
Published in Oncogene (10-10-2013)“…Notch signaling is frequently hyperactivated in breast cancer, but how the enhanced signaling contributes to the tumor process is less well understood. In this…”
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Notch activation in the mouse mammary luminal lineage leads to ductal hyperplasia and altered partitioning of luminal cell subtypes
Published in Experimental cell research (01-10-2020)“…Hyperactivated Notch signalling has been implicated in breast cancer, but how elevated levels of Notch signalling contribute to mammary dysplasia and…”
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Publisher Correction: Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination
Published in Nature communications (03-09-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Decoding breast cancer tissue-stroma interactions using species-specific sequencing
Published in Breast cancer research : BCR (13-08-2015)“…Decoding transcriptional effects of experimental tissue-tissue or cell-cell interactions is important; for example, to better understand tumor-stroma…”
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The molecular basis of Alagille syndrome: Jagged/Notch signaling in liver development and disease
Published in INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2012)Get full text
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