Search Results - "Chiurillo, Miguel Angel"

Role of gene polymorphisms in gastric cancer and its precursor lesions:Current knowledge and perspectives in Latin American countries by Chiurillo, Miguel Angel

“…Latin America shows one of the highest incidence rates of gastric cancer in the world,with variations in mortality rates among nations or even within countries…”
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Design of an allele-specific PCR assay to genotype the rs12255372 SNP in a pilot study of association between common TCF7L2 polymorphisms and type 2 diabetes in Venezuelans by Moran, Yeinmy, Labrador, Luis, Camargo, María Eugenia, Fernández, David, Chiurillo, Miguel Angel

“…The global burden of diabetes mellitus will impact strongly American countries in the coming decades. Type 2 diabetes mellitus (T2DM) is a multifactorial…”
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Can the prevalence of symptoms in patients with inflammatory bowel disease be predicted by the analysis of multidrug resistance gene 1 polymorphisms? by Chiurillo, Miguel

“…[...]the study of Bonyadi et al., raises the possibility that the analysis of genetic polymorphisms can be used to predict the severity of the symptoms and…”
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Association of common variants on chromosome 8q24 with gastric cancer in Venezuelan patients by Labrador, Luis, Torres, Keila, Camargo, Maria, Santiago, Laskhmi, Valderrama, Elvis, Chiurillo, Miguel Angel

“…Gastric cancer remains one of the leading causes of death in the world, being Central and South America among the regions showing the highest incidence and…”
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TCF7L2 rs7903146 polymorphism is associated with gastric cancer: a case-control study in the Venezuelan population by Torres, Keila, Labrador, Luis, Valderrama, Elvis, Chiurillo, Miguel Angel

“…AIM: To explore the association between TCF7L2 rs12255372 and rs7903146 single nucleotide polymorphisms(SNPs) and gastric cancer risk in Venezuelan…”
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Distribution of GSTM1, GSTT1, GSTP1 and TP53 disease-associated gene variants in native and urban Venezuelan populations by Chiurillo, Miguel Angel, Griman, Pedro, Santiago, Laskhmi, Torres, Keila, Moran, Yeinmy, Borjas, Lisbeth

“…The contemporary Venezuelan population is the product of major admixture process across various historical events, which has provided it a particular genetic…”
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Genotyping of Helicobacter pylori virulence-associated genes shows high diversity of strains infecting patients in western Venezuela by Chiurillo, Miguel Angel, Moran, Yeinmy, Cañas, Miryan, Valderrama, Elvis, Granda, Nashdalish, Sayegh, Marjorie, Ramírez, José Luis

“…Summary Background Helicobacter pylori is a major cause of chronic gastritis and an established risk factor for gastric adenocarcinoma. This bacterium also…”
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Ablation of the P21 Gene of Trypanosoma cruzi Provides Evidence of P21 as a Mediator in the Control of Epimastigote and Intracellular Amastigote Replication by Teixeira, Thaise Lara, Chiurillo, Miguel Angel, Lander, Noelia, Rodrigues, Cassiano Costa, Onofre, Thiago Souza, Ferreira, Éden Ramalho, Yonamine, Camila Miyagui, Santos, Júlia de Gouveia, Mortara, Renato Arruda, da Silva, Claudio Vieira, da Silveira, José Franco

“…P21 is an immunomodulatory protein expressed throughout the life cycle of , the etiologic agent of Chagas disease. and studies have shown that P21 plays an…”
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Study of the oipA genetic diversity and EPIYA motif patterns in cagA-positive Helicobacter pylori strains from Venezuelan patients with chronic gastritis by Torres, Keila, Valderrama, Elvis, Sayegh, Marjorie, Ramírez, José Luis, Chiurillo, Miguel Angel

“…CagA and OipA are involved, among other virulence factors, in the ability of Helicobacter pylori to colonize the gastric mucosa and to modulate the host…”
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The diversity and expansion of the trans-sialidase gene family is a common feature in Trypanosoma cruzi clade members by Chiurillo, Miguel Angel, Cortez, Danielle R., Lima, Fábio M., Cortez, Caroline, Ramírez, José Luis, Martins, Andre G., Serrano, Myrna G., Teixeira, Marta M.G., da Silveira, José Franco

“…Trans-sialidase (TS) is a polymorphic protein superfamily described in members of the protozoan genus Trypanosoma. Of the eight TS groups recently described,…”
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Infection with Specific Helicobacter pylori-cag Pathogenicity Island Strains Is Associated with Interleukin-1B Gene Polymorphisms in Venezuelan Chronic Gastritis Patients by Chiurillo, Miguel Angel, Moran, Yeinmy H, Cañas, Miryan, Valderrama, Elvis J, Armanie, Emma

“…Background The cag pathogenicity island (cag-PAI) is one of the major virulence factors of Helicobacter pylori, showing considerable geographic variation. Aim…”
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A novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi by Verbisck, Newton Valério, dos Santos, Márcia Regina Machado, Engman, David M, Angel Chiurillo, Miguel, Ramirez, José Luis, Araya, Jorge Enrique, Mortara, Renato Arruda, da Silveira, José Franco

“…We report the molecular characterization of a novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of…”
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Combination of Helicobacter pylori-iceA2 and proinflammatory interleukin-1 polymorphisms is associated with the severity of histological changes in Venezuelan chronic gastritis patients by Chiurillo, Miguel Angel, Moran, Yeinmy, Cañas, Miryan, Valderrama, Elvis, Alvarez, Alberto, Armanie, Emma

“…Helicobacter pylori is a major cause of chronic gastritis (CG) and a firmly established carcinogen for gastric adenocarcinoma. However, the underlying…”
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Detection of Trypanosoma cruzi and Trypanosoma rangeli infection by duplex PCR assay based on telomeric sequences by Chiurillo, Miguel Angel, Crisante, Gladys, Rojas, Agustina, Peralta, Andreina, Dias, Manuel, Guevara, Palmira, Añez, Néstor, Ramírez, José Luis

“…We used the species specificity and repetitious nature of subtelomeric kinetoplastida sequences to generate a duplex PCR assay for the simultaneous detection…”
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Kinetic and molecular evidences that human cardiac muscle express non-M2 muscarinic receptor subtypes that are able to interact themselves by Pérez, Carmen Carlota Nello, Tobar, Iván Darío Bravo, Jiménez, Eliézer, Castañeda, Darwin, Rivero, Maria Belén, Concepción, Juan Luís, Chiurillo, Miguel Ángel, Bonfante-Cabarcas, Rafael

“…In heart tissue five isoforms of the muscarinic acetylcholine receptor (mAChR) have been identified, designated m1–m5, of which only M1, M2 and M3 have…”
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Development of Y-SNP typing assay for forensic application in Venezuelan population by Chiurillo, Miguel Angel, Lander, Noelia, Rojas, María, Sayegh, Marjorie, Ramirez, Jose Luis

“…Single-nucleotide polymorphisms of Y-chromosome (Y-SNPs) are genetic markers that can display regional specificity, thus providing useful information about the…”
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TP53 codon 72 polymorphism and gastric cancer risk: a case-control study in individuals from the central-western region of Venezuela by Cañas, Miryan, Morán, Yeinmy, Camargo, María Eugenia, Rivero, María Belén, Bohórquez, Adolfo, Villegas, Venus, Ramírez, Eddy, Rendón, Yanet, Suárez, Alfredo, Morales, Luis, Useche, Emerson, Salazar, Sandra, Zambrano, Amado, Ramírez, Alvaro, Valderrama, Elvis, Briceño, Zuly, Chiurillo, Miguel Angel

“…Codon 72 polymorphism of the tumor suppressor gene TP53 has been associated with a higher risk in the development of several types of cancer. The polymorphism…”
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Interleukin-1 genetic polymorphism: association with gastric cancer in the high-risk Central-Western population of Venezuela by Cañas, Miryan, Morán, Yeinmy, Rivero, María Belén, Bohórquez, Adolfo, Villegas, Venus, Rendón, Yanet, Ramírez, Eddy, Valderrama, Elvis, Briceño, Zuly, Chiurillo, Miguel Angel

“…Genetic predisposition may play a role in the prevalence of gastric cancer (GC). To investigate the relationship between selected interleukin-1 (IL-1) loci…”
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Trypanosoma cruzi Letm1 is involved in mitochondrial Ca 2+ transport, and is essential for replication, differentiation, and host cell invasion by Dos Santos, Guilherme Rodrigo Rm, Rezende Leite, Ana Catarina, Lander, Noelia, Chiurillo, Miguel Angel, Vercesi, Aníbal Eugênio, Docampo, Roberto

“…Leucine zipper-EF-hand containing transmembrane protein 1 (Letm1) is a mitochondrial inner membrane protein involved in Ca and K homeostasis in mammalian…”
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Charaterization of Leishmania major Friedlin telomeric terminus by Chiurillo, Miguel Angel, Ramírez, José Luis

“…Here we have characterized Leishmania major (Friedlin) telomeric terminus (the very end) using recombinants obtained by a vector-adaptor cloning protocol. As…”
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