Search Results - "Chiu, RWK"

Genomic Analysis of Fetal Nucleic Acids in Maternal Blood by Lo, Yuk Ming Dennis, Chiu, Rossa Wai Kwun

“…The 15 years since the discovery of fetal DNA in maternal plasma have witnessed remarkable developments in noninvasive prenatal diagnosis. An understanding of…”
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Women's preference for non‐invasive prenatal DNA testing versus chromosomal microarray after screening for Down syndrome: a prospective study by Cheng, YKY, Leung, WC, Leung, TY, Choy, KW, Chiu, RWK, Lo, T‐K, Kwok, KY, Sahota, DS

“…Objective To examine preferences for follow‐up testing in women screened with high or intermediate risk for Down syndrome in the first or second trimester…”
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Detection of the Placental Epigenetic Signature of the Maspin Gene in Maternal Plasma by Stephen S. C. Chim, Yu K. Tong, Rossa W. K. Chiu, Lau, Tze K., Leung, Tse N., Lisa Y. S. Chan, Cees B. M. Oudejans, Ding, Chunming, Y. M. Dennis Lo

“…The discovery of fetal DNA in the plasma of pregnant women has opened up new approaches for noninvasive prenatal diagnosis and monitoring. Up to now, the lack…”
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Molecular evolution of the SARS coronavirus during the course of the SARS epidemic in China by He, Jian-Feng, Peng, Guo-Wen, Min, Jun, Yu, De-Wen

“…Sixty-one SARS coronavirus genomic sequences derived from the early, middle, and late phases of the severe acute respiratory syndrome (SARS) epidemic were…”
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Non-invasive prenatal diagnosis by single molecule counting technologies by Chiu, Rossa W.K, Cantor, Charles R, Lo, Y.M. Dennis

“…Non-invasive prenatal diagnosis of fetal chromosomal aneuploidies and monogenic diseases by analysing fetal DNA present in maternal plasma poses a challenging…”
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Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients by Lee, Nelson, Allen Chan, K.C., Hui, David S., Ng, Enders K.O., Wu, Alan, Chiu, Rossa W.K., Wong, Vincent W.S., Chan, Paul K.S., Wong, K.T., Wong, Eric, Cockram, C.S., Tam, John S., Sung, Joseph J.Y., Lo, Y.M. Dennis

“…The effect of corticosteroid treatment on the viral load of Severe Acute Respiratory Syndrome (SARS) patients is unknown. To compare the plasma SARS-CoV RNA…”
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mRNA of Placental Origin Is Readily Detectable in Maternal Plasma by Enders K. O. Ng, Nancy B. Y. Tsui, Lau, Tze K., Leung, Tse N., Rossa W. K. Chiu, Panesar, Nirmal S., Lydia C. W. Lit, Chan, Kam-Wing, Y. M. Dennis Lo

“…The discovery of circulating fetal nucleic acid in maternal plasma has opened up new possibilities for noninvasive prenatal diagnosis. Thus far, a gender- and…”
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Predominant Hematopoietic Origin of Cell-free DNA in Plasma and Serum after Sex-mismatched Bone Marrow Transplantation by Lui, Yanni Y.N, Chik, Ki-Wai, Chiu, Rossa W.K, Ho, Cheong-Yip, Lam, Christopher W.K, Lo, Y.M. Dennis

“…Despite current interest in the biology and diagnostic applications of cell-free DNA in plasma and serum, the cellular origin of this DNA is poorly understood…”
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Detection of SARS coronavirus RNA in the cerebrospinal fluid of a patient with severe acute respiratory syndrome by Hung, Emily C W, Chim, Stephen S C, Chan, Paul K S, Tong, Yu K, Ng, Enders K O, Chiu, Rossa W K, Leung, Chi-Bon, Sung, Joseph J Y, Tam, John S, Lo, Y M Dennis

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Prenatal exclusion of β thalassaemia major by examination of maternal plasma by Chiu, Rossa WK, Lau, Tze K, Leung, Tse N, Chow, Katherine CK, Chui, David HK, Lo, YM Dennis

“…The discovery of the presence of fetal DMA in maternal plasma has provided a new approach for non-invasive prenatal diagnosis. At present, the prenatal…”
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EDTA is a better anticoagulant than heparin or citrate for delayed blood processing for plasma DNA analysis by Lam, Nicole Y L, Rainer, Timothy H, Chiu, Rossa W K, Lo, Y M Dennis

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Hypermethylation of RASSF1A in Human and Rhesus Placentas by Chiu, Rossa W.K, Chim, Stephen S.C, Wong, Ivy H.N, Wong, Cesar S.C, Lee, Wing-Shan, To, Ka F, Tong, Joanna H.M, Yuen, Ryan K.C, Shum, Alisa S.W, Chan, John K.C, Chan, Lisa Y.S, Yuen, Jessie W.F, Tong, Yu K, Weier, Jingly F, Ferlatte, Christy, Leung, Tse N, Lau, Tze K, Lo, Kwok W, Lo, Y.M. Dennis

“…The pseudomalignant nature of the placenta prompted us to search for tumor suppressor gene hypermethylation, a phenomenon widely reported in cancer, in the…”
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Effects of Blood-Processing Protocols on Fetal and Total DNA Quantification in Maternal Plasma by Chiu, Rossa W. K, Poon, Leo L. M, Lau, Tze K, Leung, Tse N, Wong, Eric M. C, Lo, Y. M. Dennis

“…Recently, apoptotic cells have been found in plasma obtained by centrifugation of blood from pregnant women, raising the question of what constitutes plasma…”
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MS Analysis of Single-Nucleotide Differences in Circulating Nucleic Acids: Application to Noninvasive Prenatal Diagnosis by Ding, Chunming, Rossa W. K. Chiu, Lau, Tze K., Leung, Tse N., Chan, Li C., Amy Y. Y. Chan, Charoenkwan, Pimlak, Ivy S. L. Ng, Law, Hai-yang, Edmond S. K. Ma, Xu, Xiangmin, Wanapirak, Chanane, Sanguansermsri, Torpong, Liao, Can, Mary Anne Tan Jin Ai, David H. K. Chui, Cantor, Charles R., Y. M. Dennis Lo

“…The analysis of circulating nucleic acids has revealed applications in the noninvasive diagnosis, monitoring, and prognostication of many clinical conditions…”
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Quantitative Analysis of Circulating Mitochondrial DNA in Plasma by Chiu, Rossa W.K, Chan, Lisa Y.S, Lam, Nicole Y.L, Tsui, Nancy B.Y, Ng, Enders K.O, Rainer, Timothy H, Lo, Y.M. Dennis

“…Recent studies have demonstrated the existence of circulating mitochondrial DNA in plasma and serum, but the concentrations and physical characteristics of…”
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Presence of Filterable and Nonfilterable mRNA in the Plasma of Cancer Patients and Healthy Individuals by Ng, Enders K.O, Tsui, Nancy B.Y, Lam, Nicole Y.L, Chiu, Rossa W.K, Yu, Simon C.H, Wong, S.C. Cesar, Lo, Elena S.F, Rainer, Timothy H, Johnson, Philip J, Lo, Y.M. Dennis

“…As RNA is labile, we investigated whether circulating RNA in human plasma may be present in a particle-associated form. Blood was collected from 27 healthy…”
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The Concentration of Circulating Corticotropin-releasing Hormone mRNA in Maternal Plasma Is Increased in Preeclampsia by Ng, Enders K.O, Leung, Tse N, Tsui, Nancy B.Y, Lau, Tze K, Panesar, Nirmal S, Chiu, Rossa W.K, Lo, Y.M. Dennis

“…Increased fetal DNA in maternal plasma/serum has been reported in pregnancies complicated by preeclampsia. We hypothesize that fetal RNA may also be increased…”
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Quantitative Analysis and Prognostic Implication of SARS Coronavirus RNA in the Plasma and Serum of Patients with Severe Acute Respiratory Syndrome by Ng, Enders K.O, Hui, David S, Chan, K.C. Allen, Hung, Emily C.W, Chiu, Rossa W.K, Lee, Nelson, Wu, Alan, Chim, Stephen S.C, Tong, Yu K, Sung, Joseph J.Y, Tam, John S, Lo, Y.M. Dennis

“…The availability of an early diagnostic tool for severe acute respiratory syndrome (SARS) would have major public health implications. We investigated whether…”
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Noninvasive prenatal exclusion of congenital adrenal hyperplasia by maternal plasma analysis: A feasibility study by CHIU, Rossa W. K, LAU, Tze K, CHEUNG, Pik T, GONG, Zhi Q, LEUNG, Tse N, LO, Y. M

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Systematic micro-array based identification of placental mRNA in maternal plasma: towards non-invasive prenatal gene expression profiling by Tsui, N B Y, Chim, S S C, Chiu, R W K, Lau, T K, Ng, E K O, Leung, T N, Tong, Y K, Chan, K C A, Lo, Y M D

“…The data also suggest that there are no significant differences in the liberation and clearance of the studied transcripts when compared with hPL, which would…”
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