Search Results - "Chiu, Colette N"
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Modeling Dominant and Recessive Forms of Retinitis Pigmentosa by Editing Three Rhodopsin-Encoding Genes in Xenopus Laevis Using Crispr/Cas9
Published in Scientific reports (31-07-2017)“…The utility of Xenopus laevis , a common research subject for developmental biology, retinal physiology, cell biology, and other investigations, has been…”
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Synchronized Photoactivation of T4K Rhodopsin Causes a Chromophore-Dependent Retinal Degeneration That Is Moderated by Interaction with Phototransduction Cascade Components
Published in The Journal of neuroscience (04-09-2024)“…Multiple mutations in the gene cause sector retinitis pigmentosa in humans and a corresponding light-exacerbated retinal degeneration (RD) in animal models…”
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Electrophysiological Changes During Early Steps of Retinitis Pigmentosa
Published in Investigative ophthalmology & visual science (01-03-2019)“…The rhodopsin mutation P23H is responsible for a significant portion of autosomal-dominant retinitis pigmentosa, a disorder characterized by rod photoreceptor…”
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Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four Transgenic X. laevis Models of Retinitis Pigmentosa
Published in The Journal of neuroscience (25-01-2017)“…Retinitis pigmentosa (RP) is an inherited retinal degeneration (RD) that leads to blindness for which no treatment is available. RP is frequently caused by…”
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Opposing Effects of Valproic Acid Treatment Mediated by Histone Deacetylase Inhibitor Activity in Four Transgenic X. laevis Models of Retinitis Pigmentosa
Published in The Journal of neuroscience (25-01-2017)“…Retinitis pigmentosa (RP) is an inherited retinal degeneration (RD) that leads to blindness for which no treatment is available. RP is frequently caused by…”
Get full text
Journal Article