Search Results - "Chiu, Chiayu Q."
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Long-term plasticity at inhibitory synapses
Published in Current opinion in neurobiology (01-04-2011)“…Experience-dependent modifications of neural circuits and function are believed to heavily depend on changes in synaptic efficacy such as LTP/LTD. Hence, much…”
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Compartmentalization of GABAergic Inhibition by Dendritic Spines
Published in Science (American Association for the Advancement of Science) (10-05-2013)“…γ-aminobutyric acid-mediated (GABAergic) inhibition plays a critical role in shaping neuronal activity in the neocortex. Numerous experimental investigations…”
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Dopaminergic modulation of endocannabinoid-mediated plasticity at GABAergic synapses in the prefrontal cortex
Published in The Journal of neuroscience (26-05-2010)“…Similar to dopamine (DA), cannabinoids strongly influence prefrontal cortical functions, such as working memory, emotional learning, and sensory perception…”
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Optically Selective Two-Photon Uncaging of Glutamate at 900 nm
Published in Journal of the American Chemical Society (24-04-2013)“…We have synthesized a 7-diethylaminocoumarin (DEAC) derivative that allows wavelength-selective two-photon uncaging at 900 nm versus 720 nm. This new caging…”
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Transient Receptor Potential Vanilloid 1 Function at Central Synapses in Health and Disease
Published in Frontiers in cellular neuroscience (18-04-2022)“…The transient receptor potential vanilloid 1 (TRPV1), a ligand-gated nonselective cation channel, is well known for mediating heat and pain sensation in the…”
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Long-Range GABAergic Projections of Cortical Origin in Brain Function
Published in Frontiers in systems neuroscience (22-03-2022)“…The study of long-range GABAergic projections has traditionally been focused on those with subcortical origin. In the last few years, cortical GABAergic…”
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Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning
Published in Proceedings of the National Academy of Sciences - PNAS (23-08-2011)“…Rab3B, similar to other Rab3 isoforms, is a synaptic vesicle protein that interacts with the Rab3-interacting molecule (RIM) isoforms RIM1α and RIM2α as…”
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Wavelength-Selective One- and Two-Photon Uncaging of GABA
Published in ACS chemical neuroscience (15-01-2014)“…We have synthesized photolabile 7-diethylamino coumarin (DEAC) derivatives of γ-aminobutyric acid (GABA). These caged neurotransmitters efficiently release…”
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Non-canonical type 1 cannabinoid receptor signaling regulates night visual processing in the inner rat retina
Published in iScience (21-06-2024)“…Type 1 cannabinoid receptors (CB1Rs) are expressed in major retinal neurons within the rod-pathway suggesting a role in regulating night visual processing, but…”
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Preserving the balance: diverse forms of long-term GABAergic synaptic plasticity
Published in Nature reviews. Neuroscience (01-05-2019)“…Cellular mechanisms that regulate the interplay of synaptic excitation and inhibition are thought to be central to the functional stability of healthy neuronal…”
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Input-specific plasticity at excitatory synapses mediated by endocannabinoids in the dentate gyrus
Published in Neuropharmacology (01-01-2008)“…Endocannabinoids (eCBs) mediate transient and long-lasting synaptic plasticity in several brain structures. In the dentate gyrus, activation of the type 1…”
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TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus
Published in Nature neuroscience (01-12-2010)“…The authors report that the cation channel TRPV1 suppresses excitatory synaptic transmission in dentate gyrus via a Ca 2+ -calcineurin and clathrin-dependent…”
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Input-Specific NMDAR-Dependent Potentiation of Dendritic GABAergic Inhibition
Published in Neuron (Cambridge, Mass.) (17-01-2018)“…Preservation of a balance between synaptic excitation and inhibition is critical for normal brain function. A number of homeostatic cellular mechanisms have…”
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Muscarinic Regulation of Spike Timing Dependent Synaptic Plasticity in the Hippocampus
Published in Neuroscience (21-02-2021)“…•Acetylcholine modulates the synaptic efficacy at both excitatory and inhibitory synapses.•Diverse muscarinic receptors (mAChRs) regulate hippocampal function…”
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Microbiota and Diapause-Induced Neuroprotection Share a Dependency on Calcium But Differ in Their Effects on Mitochondrial Morphology
Published in eNeuro (01-07-2023)“…The balance between the degeneration and regeneration of damaged neurons depends on intrinsic and environmental variables. In nematodes, neuronal degeneration…”
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RIM1α and RIM1β Are Synthesized from Distinct Promoters of the RIM1 Gene to Mediate Differential But Overlapping Synaptic Functions
Published in The Journal of neuroscience (10-12-2008)“…At a synapse, presynaptic terminals form a specialized area of the plasma membrane called the active zone that mediates neurotransmitter release. RIM1α is a…”
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Long-term synaptic plasticity at inhibitory synapses
Published in Current opinion in neurobiology (18-02-2011)“…Experience-dependent modifications of neural circuits and function are believed to heavily depend on changes in synaptic efficacy such as LTP/LTD. Hence, much…”
Get full text
Journal Article -
18
TRPV1 activation by endogenous anandamide triggers postsynaptic LTD in dentate gyrus
Published in Nature neuroscience (14-11-2010)“…The transient receptor potential TRPV1 is a nonselective cation channel that mediates pain sensations and is commonly activated by a wide variety of exogenous…”
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RIM1alpha and RIM1beta are synthesized from distinct promoters of the RIM1 gene to mediate differential but overlapping synaptic functions
Published in The Journal of neuroscience (10-12-2008)“…At a synapse, presynaptic terminals form a specialized area of the plasma membrane called the active zone that mediates neurotransmitter release. RIM1alpha is…”
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