Search Results - "Chitta, K S"

Low expression of pro-apoptotic Bcl-2 family proteins sets the apoptotic threshold in Waldenström macroglobulinemia by Gaudette, B T, Dwivedi, B, Chitta, K S, Poulain, S, Powell, D, Vertino, P, Leleu, X, Lonial, S, Chanan-Khan, A A, Kowalski, J, Boise, L H

“…Waldenström macroglobulinemia (WM) is a proliferative disorder of IgM-secreting, lymphoplasmacytoid cells that inhabit the lymph nodes and bone marrow. The…”
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Suppression of the cell proliferation and invasion phenotypes in glioma cells by the LGI1 gene by KUNAPULI, Padmaja, CHITTA, Kasyapa S, COWELL, John K

“…The leucine-rich, glioma-inactivated (LGI1) gene, located in 10q24, was originally identified because it was interrupted and inactivated by a reciprocal…”
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In vitro plant regeneration of fig (Ficus carica L. cv. gular) using apical buds from mature trees by Kumar, V, Radha, A, Kumar Chita, S

“…A reliable procedure for multiple-shoot induction and plantlet regeneration was developed with apical buds collected from 7- to 8-year-old trees of Ficus…”
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Identification of USP14 and UCHL5 As Druggable Oncotargets in Ibrutinib-Resistant Mantle Cell Lymphoma by Paulus, Aneel, Akhtar, Sharoon, Samuel, Kelara, Yousaf, Hassan, Cogen, Davitte, Advani, Pooja, Witzig, Thomas E., Weiner, George J, Ailawadhi, Sikander, Gullbo, Joachim, Linder, Stig, Otero-Colon, Geraldo, Chitta, Kasyapa S., Chanan-Khan, Asher Alban

“…Background: The clinical impact of ibrutinib is irrefutable and has been hailed as a revolutionary treatment for several cancers, including mantle cell…”
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Targeted Disruption of USP14 and UCHL5 with the Novel Deubiquitinase Enzyme (DUB) Inhibitor, VLX1570, Induces Immense Proteotoxicity and Cell Death in Malignant Plasma Cells by Paulus, Aneel, Akhtar, Sharoon, Kuranz-Blake, Maja, Novak, Anne J., Ansell, Stephen, Gertz, Morie A, Kyle, Robert A, Martin, Peter, Coleman, Morton, Ailawadhi, Sikander, Linder, Stig, Chanan-Khan, Asher, Chitta, Kasyapa S.

“…Background: Deubiquitinating enzyme (DUB) inhibitors are an emerging class of compounds, which are increasingly being regarded for their anti-cancer activity…”
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VLX1570, a First in Class Dub Inhibitor, Modulates BCR Signaling and CXCR4 Expression and Demonstrates Significant In Vivo Antitumor Activity in a Murine Model of Human Waldenstrom Macroglobulinemia by Paulus, Aneel, Akhtar, Sharoon, Samuel, Kelara, Yousaf, Hassan, Cogen, Davitte, Jiang, Jennifer, Swaika, Abhisek, Novak, Anne, Ansell, Stephen M, Gertz, Morie A, Kyle, Robert A., Witzig, Thomas E., Weiner, George J, Martin, Peter, Coleman, Morton, Ailawadhi, Sikander, Gullbo, Joachim, Linder, Stig, Otero-Colon, Geraldo, Roy, Vivek, Chitta, Kasyapa S., Chanan-Khan, Asher Alban

“…Background: Aberrant B-cell receptor (BCR) and MYD88 signaling cooperatively drive Waldenstrom macroglobulinemia (WM) tumor cell survival. To sustain…”
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Insights from Streptococcus pneumonlae glucose kinase structural model by Mulakayala, C, Banaganapalli, B N, Anuradha, C M, Chitta, S K

“…Streptococcus pneumonia is the common cause of sepsis and meningitb. Emergence of multiple antibiotic resistant strains in the community-acquired bacterium is…”
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Targeted treatment for chronic lymphocytic leukemia by Masood, Aisha, Sher, Taimur, Paulus, Aneel, Miller, Kena C, Chitta, Kasyapa S, Chanan-Khan, Asher

“…The treatment of chronic lymphocytic leukemia (CLL) has evolved over the last few decades. Recognition has increased of several key components of CLL biology…”
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