Search Results - "Chiswell, David J"

Phage antibodies: filamentous phage displaying antibody variable domains by McCafferty, John, Griffiths, Andrew D, Winter, Greg, Chiswell, David J

“…New ways of making antibodies have recently been demonstrated using gene technology. Immunoglobulin variable (V) genes are amplified from hybridomas or B cells…”
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Multi-subunit proteins on the surface of filamentous phage : methodologies for displaying antibody (Fab) heavy and light chains by HOOGENBOOM, H. R, GRIFFITHS, A. D, JOHNSON, K. S, CHISWELL, D. J, HUDSON, P, WINTER, G

“…The display of proteins on the surface of phage offers a powerful means of selecting for rare genes encoding proteins with binding activities. Recently we…”
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Phage antibodies: will new 'coliclonal' antibodies replace monoclonal antibodies? by Chiswell, D J, McCafferty, J

“…Antibodies can now be rapidly isolated from large and diverse recombinant libraries by displaying functional antibody fragments on the surface of bacteriophage…”
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Phage-enzymes: expression and affinity chromatography of functional alkaline phosphatase on the surface of bacteriophage by McCafferty, J, Jackson, R H, Chiswell, D J

“…We have demonstrated that an active enzyme can be expressed on the surface of a bacteriophage. The gene encoding alkaline phosphatase from Escherichia coli was…”
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Selection and rapid purification of murine antibody fragments that bind a transition-state analog by phage display by McCafferty, J, Fitzgerald, K J, Earnshaw, J, Chiswell, D J, Link, J, Smith, R, Kenten, J

“…Functional antibody fragments may be displayed on the surface of filamentous bacteriophage by introducing variable region genes into the viral genome at a gene…”
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Phage Display of Ricin B Chain and its Single Binding Domains: System for Screening Galactose-Binding Mutants by Swimmer, Candace, Lehar, Sophie M., McCafferty, John, Chiswell, David J., Blattler, Walter A., Guild, Braydon C.

“…We demonstrate that the B chain of ricin toxin preserves its lectin activity when expressed as a fusion protein on the surface of fd phage. Moreover, B chain,…”
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Analysis of the variations in proviral cytosine methylation that accompany transformation and morphological reversion in a line of Rous sarcoma virus-infected Rat-1 Cells by Searle, Siâ, Gillespie, David A.F., Chiswell, David J., Wyke, John A.

“…Cells of the All lineage of Rat-1 contain a single complete Rous sarcoma provirus. Variation in the activity of this provirus accompanies fluctuations in the…”
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Molecular mechanisms involved in morphological variation of avian sarcoma virus-infected rat cells by Chiswell, D J, Enrietto, P J, Evans, S, Quade, K, Wyke, J A

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The changes in proviral chromatin that accompany morphological variation in avian sarcoma virus-infected rat cells by Chiswell, David J., Gillespie, David A., Wyke, John A.

“…The clone All of avian sarcoma virus B77-infected Rat-1 cells comprises both morphologically normal and morphologically transformed derivatives. Transformed…”
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Mapping of nonconditional and conditional mutants in the src gene of Prague strain Rous sarcoma virus by Fincham, V J, Chiswell, D J, Wyke, J A

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