Search Results - "Chiroma, Musa Samaila"
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Curcumin Attenuates Lead-Induced Cerebellar Toxicity in Rats via Chelating Activity and Inhibition of Oxidative Stress
Published in Biomolecules (Basel, Switzerland) (06-09-2019)“…Lead (Pb) is a toxic, environmental heavy metal that induces serious clinical defects in all organs, with the nervous system being its primary target. Curcumin…”
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Cockle Shell-Derived Calcium Carbonate (Aragonite) Nanoparticles: A Dynamite to Nanomedicine
Published in Applied sciences (01-07-2019)“…Cockle shell is an external covering of small, salt water edible clams (Anadara granosa) that dwells in coastal area. This abundant biomaterial is hard, cheap…”
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Protective effect of Centella asiatica against D-galactose and aluminium chloride induced rats: Behavioral and ultrastructural approaches
Published in Biomedicine & pharmacotherapy (01-01-2019)“…[Display omitted] •D-galactose 60/AlCl3 200(mg/kg.bw) induced cognitive deficits in rats.•Neurodegeneration was observed in the demented rats.•Centella…”
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4
Centella asiatica Protects d-Galactose/AlCl3 Mediated Alzheimer’s Disease-Like Rats via PP2A/GSK-3β Signaling Pathway in Their Hippocampus
Published in International journal of molecular sciences (16-04-2019)“…Alzheimer’s disease (AD) is a progressive neurodegenerative disorder more prevalent among the elderly population. AD is characterised clinically by a…”
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5
Effects of Sub-acute Administration of Onion Waste Quercetin on the Hippocampus of Mice: A Histological Approach
Published in GAZI UNIVERSITY JOURNAL OF SCIENCE (01-01-2024)“…Quercetin is a flavonoid with a great capability of crossing the blood-brain barrier. It is reported to exert numerous beneficial effects on both animal and…”
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Antioxidant-based neuroprotective effect of dimethylsulfoxide against induced traumatic brain injury in a rats model
Published in Frontiers in pharmacology (06-10-2022)“…Traumatic brain injury (TBI) has been the result of neurological deficit and oxidative stress. This study evaluated the antioxidative neuroprotective property…”
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Acute Toxicity Study of Methanol Extract of Baobab (Adansonia digitata Linn) Fruit Shell Extract in Mice
Published in Pharmaceutical and biomedical research (01-09-2023)“…Background: The natural origin of medicinal plants does not guarantee their safety, as there are no sufficient studies on the safety, efficacy, and toxicity to…”
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Iron Deficiency in Pregnancy: A Brief Review
Published in Journal of medical science (28-06-2023)“…This paper highlights iron deficiency anaemia in pregnancy; its prevalence, causes, screening, and management. Iron deficiency is a spectrum that ranges from…”
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Centella asiatica ameliorates AlCl3 and D-galactose induced nephrotoxicity in rats via modulation of oxidative stress
Published in Bioinformation (31-05-2024)“…Nephrotoxicity is a condition caused by toxic effects of medications and poisons resulting in the rapid decline of kidney function. is a medicinal herb with…”
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Antioxidant and anti-inflammatory properties of Erythroxylum cuneatum alkaloid leaf extract
Published in Heliyon (01-06-2020)“…Erythroxylum cuneatum (E. cuneatum) which belongs to Erythroxylaceae family is a tropical flowering plant from the genus of Erythroxylum. It is used in…”
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Exploring the antioxidant effects of Aloe vera: Potential role in controlling liver function and lipid profile in high fat and fructose diet (HFFD) fed mice
Published in Pharmacological research. Modern Chinese medicine (01-09-2022)“…Fat-rich diets are believed to induce obesity and contribute to the development of diabetes and cardiovascular disease in contrast high fructose diet was…”
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12
Adansonia digitata L. Stem Bark Attenuates Epileptic Seizure, Depression, and Neurodegeneration by Mediating GABA and Glutamate in Pentylenetetrazol-Kindled Rats
Published in Journal of pharmacopuncture (31-12-2023)“…Epilepsy is a neurological condition characterized by repeated seizures attributable to synchronous neuronal activity in the brain. The study evaluated the…”
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Phytochemical screening and in-vitro antioxidant activities of aqueous and methanol extracts of Aloe vera
Published in Pharmacological research. Modern Chinese medicine (01-09-2023)“…•The aqueous and methanol extract of AV revealed the presence of phenols, tannins, and flavonoids.•The methanol extract of AV produced a better-reducing power…”
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Curcumin‐loaded cockle shell‐derived calcium carbonate nanoparticles ameliorates lead‐induced neurotoxicity in rats via attenuation of oxidative stress
Published in Food science & nutrition (01-05-2023)“…A substantial global health burden is associated with neurotoxicity caused by lead (Pb) exposure and the common mechanism of this toxicity is mainly via…”
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Menhaden fish oil attenuates postpartum depression in rat model via inhibition of NLRP3-inflammasome driven inflammatory pathway
Published in Journal of Traditional and Complementary Medicine (01-09-2021)“…Background and aim: Postpartum depression (PPD) is a familiar problem which is associated with about 10-20% of women after child delivery. Fish oil (FO) has a…”
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Neuroprotective roles of flavonoid "hispidulin" in the central nervous system: A review
Published in Iranian journal of basic medical sciences (01-01-2024)“…Interest in naturally occurring phytochemicals has been on the increase, they are believed to reduce the risk of brain disorders. Hispidulin (HN) is a phenolic…”
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Centella asiatica prevents chronic unpredictable mild stress-induced behavioral changes in rats
Published in Biomedical research and therapy (30-06-2019)“…Background: Depression is a psychological disorder which is associated with mood swings and cognitive deficits, and is ranked third among the leading causes of…”
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Aloe vera Gel Ameliorates Fat-Rich and High Fructose (FRHF) Diet-Induced Pancreatic and Splenic Damage in Mice
Published in Borneo Journal of Pharmacy (30-08-2023)“…High-fat diet alone or in combination with high fructose has been known to induce diabetes, obesity, hypertension, and immune dysfunction. The study evaluates…”
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Toxoplasma gondii induced cognitive impairment in rats via dysregulation of dopamine receptors and indoleamine 2,3 dioxygenase
Published in Heliyon (01-03-2023)“…Toxoplasma gondii (T. gondii) is a parasite capable of residing in the brain of their host which influences behaviour changes due to alterations in the…”
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WIN55,212-2 Attenuates Cognitive Impairments in AlCl3 + d-Galactose-Induced Alzheimer’s Disease Rats by Enhancing Neurogenesis and Reversing Oxidative Stress
Published in Biomedicines (19-09-2021)“…Neurotransmission and cognitive dysfunctions have been linked to old age disorders including Alzheimer’s disease (AD). Aluminium is a known neurotoxic metal,…”
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