Search Results - "Chirdo, Fernando Gabriel"

IL-1β blockade prevents cell death and mucosal damage of the small intestine in a model of sterile inflammation by Ruera, Carolina, Miculan, Emanuel, Ducca, Gerónimo, Pérez, Federico, Iribarren, María Luz, Carasi, Paula, Chirdo, Gabriel Fernando

“…•Intragastric administration of a single dose of gliadin peptide p31–43 causes mucosal damage and cell death in the proximal small intestine.•Inhibition of…”
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Programmed Cell Death in the Small Intestine: Implications for the Pathogenesis of Celiac Disease by Perez, Federico, Ruera, Carolina Nayme, Miculan, Emanuel, Carasi, Paula, Chirdo, Fernando Gabriel

“…The small intestine has a high rate of cell turnover under homeostatic conditions, and this increases further in response to infection or damage. Epithelial…”
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p31-43 Gliadin Peptide Forms Oligomers and Induces NLRP3 Inflammasome/Caspase 1- Dependent Mucosal Damage in Small Intestine by Gómez Castro, María Florencia, Miculán, Emanuel, Herrera, María Georgina, Ruera, Carolina, Perez, Federico, Prieto, Eduardo Daniel, Barrera, Exequiel, Pantano, Sergio, Carasi, Paula, Chirdo, Fernando Gabriel

“…Celiac disease (CD) is a chronic enteropathy elicited by a Th1 response to gluten peptides in the small intestine of genetically susceptible individuals…”
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Inflammation Is Present, Persistent and More Sensitive to Proinflammatory Triggers in Celiac Disease Enterocytes by Porpora, Monia, Conte, Mariangela, Lania, Giuliana, Bellomo, Claudia, Rapacciuolo, Luciano, Chirdo, Fernando Gabriel, Auricchio, Renata, Troncone, Riccardo, Auricchio, Salvatore, Barone, Maria Vittoria, Nanayakkara, Merlin

“…Celiac disease (CD) is a chronic inflammatory disease caused by a genetic predisposition to an abnormal T cell-mediated immune response to the gluten in the…”
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The gliadin p31-43 peptide: Inducer of multiple proinflammatory effects by Chirdo, Fernando Gabriel, Auricchio, Salvatore, Troncone, Riccardo, Barone, Maria Vittoria

“…Coeliac disease (CD) is the prototype of an inflammatory chronic disease induced by food. In this context, gliadin p31-43 peptide comes into the spotlight as…”
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Duodenal mucosa of untreated celiac disease patients has altered expression of the GAS6 and PROS1 and the negative regulator tyrosine kinase TAM receptors subfamily by Perez, Federico, Iribarren, María Luz, Olexen, Cinthia Mariel, Ruera, Carolina Naymé, Errasti, Andrea Emilse, Guzman, Luciana, Garbi, Laura, Carrera Silva, Eugenio Antonio, Chirdo, Fernando Gabriel

“…Celiac disease (CD) is an immune-driven disease characterized by tissue damage in the small intestine of genetically-susceptible individuals. We evaluated here…”
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Preparative Fractionation of Gliadins by Electrophoresis at pH 3.1 (A-PAGE) by Rumbo, Martin, Chirdo, Fernando Gabriel, Giorgieri, Sergio Alejandro, Fossati, Carlos Alberto, Añón, Maria Cristina

“…Purification of gliadin subclasses has been difficult since they share many biochemical and physicochemical properties. In this report, the optimization of a…”
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Production of the Main Celiac Disease Autoantigen by Transient Expression in Nicotiana benthamiana by Marín Viegas, Vanesa S, Acevedo, Gonzalo R, Bayardo, Mariela P, Chirdo, Fernando G, Petruccelli, Silvana

“…Celiac Disease (CD) is a gluten sensitive enteropathy that remains widely undiagnosed and implementation of massive screening tests is needed to reduce the…”
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Immunochemical reactivity of soybeanβ-conglycinin subunits by Petruccelli, S, Chirdo, F.G, Anon, M.C

“…The immunochemical reactivity of two polyclonal sera raised against soybean purified αα' and β subunits was analysed. We show that anti-αα' serum mainly reacts…”
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In vitro presentation of gliadin-derived peptides by different cell lines by Chirdo, Fernando Gabriel, Zwirner, Norberto Walter, Rumbo, Martı́n, Fossati, Carlos Alberto

“…Background: Gliadin peptide presentation and T-cell activation are critical events in the pathogenesis of celiac disease. Several studies have been performed…”
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Fractionation of secalins and hordeins by preparative electrophoresis at acid pH by Rumbo, Martin, Margheritis, Analia, Chirdo, Fernando, Giorgieri, Sergio, Fossati, Carlos, Añón, Maria

“…In this report, the optimization of a preparative electrophoretic method to fractionate secalins and hordeins is described. Separation was performed in…”
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Development of high-sensitive enzyme immunoassays for gliadin quantification using the streptavidin-biotin amplification system by Chirdo, Fernando Gabriel, Añón, María Cristina, Fossati, Carlos Alberto

“…Optimization of three enzyme immunoassays of very high sensitivity using three antiprolamin monoclonal antibodies (MAbs) (13B4, 11C4 and 12A1) is presented…”
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Analysis of anti-prolamin monoclonal antibody reactivity using prolamin fractions purified by preparative electrophoresis by Rumbo, M, Chirdo, F.G, Fossati, C.A, Anon, M.C

“…Coeliac disease (CD) is a gastrointestinal afliction triggered by the ingestion of prolamins from wheat, barley, rye and possibly oats. The only treatment for…”
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Immunoblotting of gliadins separated by acid PAGE: Analysis of electrotransference conditions by Rumbo, Martin, Chirdo, Fernando Gabriel, Añón, Maria Cristina, Añón, Maria Cristina, Fossati, Carlos Alberto

“…Several transference buffers and conditions (time and voltage) were tested to establish a suitable procedure for immunoblotting of gliadins after acid…”
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