Search Results - "Chiranjeevi, Padala"
-
1
In silico identification of single nucleotide variations at CpG sites regulating CpG island existence and size
Published in Scientific reports (04-03-2022)“…Genetic and epigenetic modifications of genes involved in the key regulatory pathways play a significant role in the pathophysiology and progression of…”
Get full text
Journal Article -
2
Synergistic effect of collagenase-1 (MMP1), stromelysin-1 (MMP3) and gelatinase-B (MMP9) gene polymorphisms in breast cancer
Published in PloS one (29-09-2017)“…Extracellular matrix degradation by matrix metalloproteinases (MMPs) is an important mechanism involved in tumor invasion and metastasis. Genetic variations of…”
Get full text
Journal Article -
3
Association of CYBA gene (-930 A/G and 242 C/T) polymorphisms with oxidative stress in breast cancer: a case-control study
Published in PeerJ (San Francisco, CA) (04-10-2018)“…Oxidative stress (OS) is a key characteristic feature in cancer initiation and progression. Among multiple cancers, NADPH oxidase (NOX) dependent free radical…”
Get full text
Journal Article -
4
Biodegradable and biocompatible nonisocyanate polyurethanes synthesized from bio-derived precursors
Published in Polymer (Guilford) (12-09-2024)“…Despite the enormous use of polyurethanes (PUs) in multiple aspects of modern lifestyle, the industrial scale manufacturing of PUs uses toxic chemicals like…”
Get full text
Journal Article -
5
HPIP protooncogene differentially regulates metabolic adaptation and cell fate in breast cancer cells under glucose stress via AMPK and RNF2 dependent pathways
Published in Cancer letters (10-10-2021)“…While cancer cells rewire metabolic pathways to sustain growth and survival under metabolic stress in solid tumors, the molecular mechanisms underlying these…”
Get full text
Journal Article -
6
In-vitro biomineralization, mechanical properties and drug release efficacy of tantalum containing borophosphate bioactive glasses
Published in Journal of drug delivery science and technology (01-06-2023)“…Ta2O5 additive borophosphate glasses having composition (40 B2O3 – 20 CaO – 25 Li2O – (15-X) P2O5 – X Ta2O5 (mol %); where X = 0, 0.5, 1.0, 2.0, 3.0) were…”
Get full text
Journal Article -
7
Hematopoietic PBX‐interacting protein is a novel regulator of mammary epithelial cell differentiation
Published in The FEBS journal (01-03-2022)“…Hematopoietic PBX‐interacting protein (HPIP, also known as PBXIP1) is an estrogen receptor (ER) interacting protein that regulates estrogen‐mediated breast…”
Get full text
Journal Article -
8
Structural and in vitro biological properties of strontium substituted bio-waste derived wollastonite for bone regeneration
Published in Ceramics international (15-11-2023)“…Strontium (Sr) substituted wollastonite bioceramics were prepared by a modified sol-gel technique using bio-wastes such as eggshell as calcium oxide source and…”
Get full text
Journal Article -
9
A novel cost-effective approach to fabricate diopside bioceramics: A promising ceramics for orthopedic applications
Published in Advanced powder technology : the international journal of the Society of Powder Technology, Japan (01-03-2021)“…[Display omitted] •The tendency to use bio-waste in the production of bioceramics.•Diopside was obtained from rice husk ash and eggshells at a temperature of…”
Get full text
Journal Article -
10
Genotypic and haplotype analysis of Interleukin-6 and -18 gene polymorphisms in association with clinicopathological factors in breast cancer
Published in Cytokine (Philadelphia, Pa.) (01-12-2022)“…•To understand the clinical importance of IL6 and IL18 gene variants in progression of breast cancer and to help in identifying individuals at risk of…”
Get full text
Journal Article -
11
A reciprocal feedback loop between HIF-1α and HPIP controls phenotypic plasticity in breast cancer cells
Published in Cancer letters (01-02-2022)“…While phenotypic plasticity is a critical factor contributing to tumor heterogeneity, molecular mechanisms underlying this process are largely unknown. Here we…”
Get full text
Journal Article -
12
-
13
Collagenase-1 (-1607 1G/2G), Gelatinase-A (-1306 C/T), Stromelysin-1 (-1171 5A/6A) functional promoter polymorphisms in risk prediction of type 2 diabetic nephropathy
Published in Gene (05-10-2018)“…Type 2 Diabetic Nephropathy (DN) is a common multifactorial disorder. Degradation of glomerular basement membrane (GBM) by matrix metalloproteases (MMPs) is a…”
Get full text
Journal Article -
14
PCSK9 genetic (rs11591147) and epigenetic (DNA methylation) modifications associated with PCSK9 expression and serum proteins in CAD patients
Published in The journal of gene medicine (01-08-2021)“…Introduction Proprotein convertase subtilisin/kexin type 9 (PCSK9) genetic polymorphisms play a significant role in cholesterol homeostasis. Therefore, we…”
Get full text
Journal Article -
15
MMP 1 circulating levels and promoter polymorphism in risk prediction of coronary artery disease in asymptomatic first degree relatives
Published in Gene (20-12-2016)“…Coronary artery disease (CAD) remains to be the prominent health problem in India, and its incidence is growing in developing countries as well. Matrix…”
Get full text
Journal Article -
16
Polymorphic variants of Caspase genes (8 & 3) in the risk prediction of Coronary Artery Disease
Published in Gene (05-09-2017)“…Apoptosis has been involved in a number of pathological conditions including coronary artery disease (CAD). Caspases (CASP) are important regulators and…”
Get full text
Journal Article -
17
Genetic polymorphisms of eNOS (-786T/C, Intron 4b/4a & 894G/T) and its association with asymptomatic first degree relatives of coronary heart disease patients
Published in Nitric oxide (30-11-2016)“…The eNOS gene has been extensively screened for important variations in the promoter (-786T/C), Intron 4 (4b/4a) and exon 7 (894G/T) regions in multiple…”
Get full text
Journal Article -
18
Synergistic effect of collagenase-1 gene polymorphisms in breast cancer
Published in PloS one (29-09-2017)“…Background Extracellular matrix degradation by matrix metalloproteinases (MMPs) is an important mechanism involved in tumor invasion and metastasis. Genetic…”
Get full text
Journal Article -
19
Synergistic effect of collagenase-1
Published in PloS one (29-09-2017)“…Background Extracellular matrix degradation by matrix metalloproteinases (MMPs) is an important mechanism involved in tumor invasion and metastasis. Genetic…”
Get full text
Journal Article -
20
Rrp1B gene polymorphism (1307T>C) in metastatic progression of breast cancer
Published in Tumor biology (01-02-2015)“…Rrp1B (ribosomal RNA processing1 homolog B) is a novel candidate metastasis modifier gene in breast cancer. Functional gene assays demonstrated that a physical…”
Get full text
Journal Article