Search Results - "Chippalkatti, Rohan"

RAS isoform specific activities are disrupted by disease associated mutations during cell differentiation by Chippalkatti, Rohan, Parisi, Bianca, Kouzi, Farah, Laurini, Christina, Ben Fredj, Nesrine, Abankwa, Daniel Kwaku

“…The RAS-MAPK-pathway is aberrantly regulated in cancer and developmental diseases called RASopathies. While typically the impact of Ras on the proliferation of…”
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Mms19 promotes spindle microtubule assembly in Drosophila neural stem cells by Chippalkatti, Rohan, Egger, Boris, Suter, Beat

“…Mitotic divisions depend on the timely assembly and proper orientation of the mitotic spindle. Malfunctioning of these processes can considerably delay…”
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A flow-cytometry-based pipeline for the rapid quantification of C2C12 cell differentiation by Parisi, Bianca, Sünnen, Maxime, Chippalkatti, Rohan, Abankwa, Daniel Kwaku

“…The C2C12 cell line represents a simple in vitro model for cell differentiation. Here, we present a flow-cytometry-based pipeline to quantitate C2C12 cell…”
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Promotion of cancer cell stemness by Ras by Chippalkatti, Rohan, Abankwa, Daniel

“…Cancer stem cells (CSC) may be the most relevant and elusive cancer cell population, as they have the exquisite ability to seed new tumors. It is plausible,…”
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Drug targeting opportunities en route to Ras nanoclusters by Pavic, Karolina, Chippalkatti, Rohan, Abankwa, Daniel

“…Disruption of the native membrane organization of Ras by the farnesyltransferase inhibitor tipifarnib in the late 1990s constituted the first indirect approach…”
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Advanced microscope studies of the cell polarization instructing activity of Ras proteins by Rouzbahani, Yashar, Chippalkatti, Rohan, Abankwa, Daniel, Carravilla, Pablo, Eggeling, Christian

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ERK regulates mitochondrial membrane potential in fission deficient Drosophila follicle cells during differentiation by Tomer, Darshika, Chippalkatti, Rohan, Mitra, Kasturi, Rikhy, Richa

“…Mitochondrial morphology regulatory proteins interact with signaling pathways involved in differentiation. In Drosophila oogenesis, EGFR signaling regulates…”
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Dual Drug Conjugated Nanoparticle for Simultaneous Targeting of Mitochondria and Nucleus in Cancer Cells by Mallick, Abhik, More, Piyush, Ghosh, Sougata, Chippalkatti, Rohan, Chopade, Balu A, Lahiri, Mayurika, Basu, Sudipta

“…Effective targeting of mitochondria has emerged as an alternative strategy in cancer chemotherapy. However, considering mitochondria’s crucial role in cellular…”
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Novel platinum-palladium bimetallic nanoparticles synthesized by Dioscorea bulbifera: anticancer and antioxidant activities by Ghosh, Sougata, Nitnavare, Rahul, Dewle, Ankush, Tomar, Geetanjali B, Chippalkatti, Rohan, More, Piyush, Kitture, Rohini, Kale, Sangeeta, Bellare, Jayesh, Chopade, Balu A

“…Medicinal plants serve as rich sources of diverse bioactive phytochemicals that might even take part in bioreduction and stabilization of phytogenic…”
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Abstract 3493: Drug targeting of KRAS accumulation on the cilium inhibits its stemness driving activity by Kaya, Pelin, Chippalkatti, Rohan, Schaffner-Reckinger, Elisabeth, Parisi, Bianca, Manoharan, Ganesh B., Rouzbahani, Yashar, Eggeling, Christian, Abankwa, Daniel

“…Abstract Most RAS drug targeting strategies focus on KRAS, due to the high KRAS mutation frequency in cancer and its high expression level. Moreover, KRAS4B…”
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