Search Results - "Chipepo Kankasa"
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Feasibility of using infant testing during immunization to estimate HIV mother-to-child-transmission rates in Zambia
Published in BMC infectious diseases (09-12-2021)“…Abstract Background This study piloted the feasibility of infant testing in immunization services as a strategy for estimating MTCT rates among the population…”
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2
Breastmilk cell trafficking induces microchimerism‐mediated immune system maturation in the infant
Published in Pediatric allergy and immunology (01-03-2018)“…Initiating breastfeeding within the first hour of life confers an important benefit in terms of child mortality and severe morbidity. Intestinal permeability…”
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3
Human milk oligosaccharide concentration and risk of postnatal transmission of HIV through breastfeeding
Published in The American journal of clinical nutrition (01-10-2012)“…The inefficiency of HIV breast-milk transmission may be caused by the presence of immunologically active factors, including human milk oligosaccharides (HMOs)…”
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4
Oligosaccharide composition of breast milk influences survival of uninfected children born to HIV-infected mothers in Lusaka, Zambia
Published in The Journal of nutrition (01-01-2015)“…Human milk oligosaccharides (HMOs) have multiple immunomodulatory functions that influence child health. In this study we investigated whether HMO composition…”
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5
Growth, clinical and neurodevelopmental outcomes at school age are similar for children who received 1-year lamivudine or lopinavir/ritonavir HIV prophylaxis in early life
Published in Scientific reports (04-02-2021)“…In the ANRS 12174 trial, HIV-exposed uninfected African neonates who received lopinavir-ritonavir (LPV/r) prophylaxis for 1 year exhibited slower growth from…”
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Pediatric malignancies, treatment outcomes and abandonment of pediatric cancer treatment in Zambia
Published in PloS one (21-02-2014)“…There exist significant challenges to the receipt of comprehensive oncologic treatment for children diagnosed with cancer in sub-Saharan Africa. To better…”
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Exclusive breastfeeding promotion by peer counsellors in sub-Saharan Africa (PROMISE-EBF): a cluster-randomised trial
Published in The Lancet (British edition) (2011)“…Summary Background Exclusive breastfeeding (EBF) is reported to be a life-saving intervention in low-income settings. The effect of breastfeeding counselling…”
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Combination of serological and cytokine release assays for improved diagnosis of childhood tuberculosis in Zambia (PROMISE-TB)
Published in International journal of infectious diseases (01-11-2024)“…•Diagnostic gaps for childhood tuberculosis are significant in low-resource countries.•Statistical analysis selected antigen 85B antibodies,…”
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Recurrent Severe Subclinical Mastitis and the Risk of HIV Transmission Through Breastfeeding
Published in Frontiers in immunology (04-03-2022)“…Subclinical mastitis (SCM) is an important risk factor of postnatal HIV-1 transmission that is still poorly understood. A longitudinal sub-study of the…”
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10
Evaluation of a density-based rapid diagnostic test for sickle cell disease in a clinical setting in Zambia
Published in PloS one (09-12-2014)“…Although simple and low-cost interventions for sickle cell disease (SCD) exist in many developing countries, child mortality associated with SCD remains high,…”
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Sexual and reproductive health behavior and unmet needs among a sample of adolescents living with HIV in Zambia: a cross-sectional study
Published in Reproductive health (27-03-2018)“…Adolescents living with HIV face challenges, such as disclosure of HIV status, adherence to antiretroviral therapy, mental health, and sexual and reproductive…”
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12
Pregnancy loss and role of infant HIV status on perinatal mortality among HIV-infected women
Published in BMC pediatrics (31-08-2012)“…HIV-infected women, particularly those with advanced disease, may have higher rates of pregnancy loss (miscarriage and stillbirth) and neonatal mortality than…”
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Healthy pregnancies and essential fats: focus group discussions with Zambian women on dietary need and acceptability of a novel RUSF containing fish oil DHA
Published in BMC pregnancy and childbirth (10-02-2020)“…Nut butter-based Ready to Use Supplemental Foods (RUSF) are an effective way to add nutrients and calories to diets of malnourished and food insecure…”
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14
High uptake of exclusive breastfeeding and reduced early post-natal HIV transmission
Published in PloS one (26-12-2007)“…Empirical data showing the clear benefits of exclusive breastfeeding (EBF) for HIV prevention are needed to encourage implementation of lactation support…”
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Higher levels of neutralizing antibodies against KSHV in KS patients compared to asymptomatic individuals from Zambia
Published in PloS one (14-08-2013)“…Kaposi sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi Sarcoma (KS), the most common cancer diagnosed in HIV- infected patients. The…”
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Facilitators and barriers to infant post-natal HIV prophylaxis, a qualitative sub-study of the PROMISE-EPI trial in Lusaka, Zambia
Published in Frontiers in public health (17-08-2023)“…Background Infant post-natal prophylaxis (PNP) is used to prevent HIV transmission through breastfeeding. The WHO edited recommendations but so far there is no…”
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The CD133 + Stem/Progenitor-Like Cell Subset Is Increased in Human Milk and Peripheral Blood of HIV-Positive Women
Published in Frontiers in cellular and infection microbiology (24-09-2020)“…Human milk is a significant source of different CD133 and/or CD34 stem/progenitor-like cell subsets in healthy women but their cell distribution and…”
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Single-dose tenofovir and emtricitabine for reduction of viral resistance to non-nucleoside reverse transcriptase inhibitor drugs in women given intrapartum nevirapine for perinatal HIV prevention: an open-label randomised trial
Published in The Lancet (British edition) (17-11-2007)“…Summary Background Intrapartum and neonatal single-dose nevirapine are essential components of perinatal HIV prevention in resource-constrained settings, but…”
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Long-Term Persistence of Mitochondrial DNA Instability in HIV-Exposed Uninfected Children during and after Exposure to Antiretroviral Drugs and HIV
Published in Biomedicines (25-07-2022)“…HIV-exposed uninfected (HEU) children show impaired health outcomes during childhood. A high rate of mitochondrial DNA (mtDNA) instability was reported in the…”
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Adolescents' Experiences and Their Suggestions for HIV Serostatus Disclosure in Zambia: A Mixed-Methods Study
Published in Frontiers in public health (15-12-2017)“…HIV serostatus disclosure is an immense challenge for adolescents living with HIV, their caregivers, and health workers. In Zambia, however, little guidance is…”
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