Search Results - "Chiou, Shene"
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A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation
Published in Nature communications (28-09-2023)“…Across the globe, 2-3% of humans carry the p.Ser132Pro single nucleotide polymorphism in MLKL , the terminal effector protein of the inflammatory form of…”
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Lithium administered to pregnant, lactating and neonatal rats: entry into developing brain
Published in Fluids and barriers of the CNS (07-12-2021)“…Little is known about the extent of drug entry into developing brain, when administered to pregnant and lactating women. Lithium is commonly prescribed for…”
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MLKL deficiency protects against low-grade, sterile inflammation in aged mice
Published in Cell death and differentiation (01-04-2023)“…MLKL and RIPK3 are the core signaling proteins of the inflammatory cell death pathway, necroptosis, which is a known mediator and modifier of human disease…”
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An immunohistochemical atlas of necroptotic pathway expression
Published in EMBO molecular medicine (15-05-2024)“…Necroptosis is a lytic form of regulated cell death reported to contribute to inflammatory diseases of the gut, skin and lung, as well as ischemic-reperfusion…”
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