Search Results - "Chiorazzi, A"

Chemotherapy-induced peripheral neuropathy: What do we know about mechanisms? by Carozzi, V.A., Canta, A., Chiorazzi, A.

“…•Platins, taxanes, vincalkaloids, proteasome inhibitors are effective anticancer drugs.•Clinical use causes peripheral neurotoxicity impairing patients’…”
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Neurophysiological and neuropathological characterization of new murine models of chemotherapy-induced chronic peripheral neuropathies by Carozzi, V.A., Canta, A., Oggioni, N., Sala, B., Chiorazzi, A., Meregalli, C., Bossi, M., Marmiroli, P., Cavaletti, G.

“…Cisplatin, paclitaxel and bortezomib belong to some of the most effective families of chemotherapy drugs for solid and haematological cancers. Epothilones…”
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Bortezomib Treatment Produces Nocifensive Behavior and Changes in the Expression of TRPV1, CGRP, and Substance P in the Rat DRG, Spinal Cord, and Sciatic Nerve by Melis, T., Del Fiacco, M., Meregalli, C., Chiorazzi, A., Renn, C. L., Cavaletti, G., Marmiroli, P., Quartu, M., Boi, M., Picci, C., Poddighe, L., Carozzi, V. A., Dorsey, Susan G., Serra, M. P.

“…To investigate neurochemical changes associated with bortezomib-induced painful peripheral neuropathy (PN), we examined the effects of a single-dose…”
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In vivo comparative study of the cytotoxicity of a liposomal formulation of cisplatin (lipoplatin™) by Canta, A., Chiorazzi, A., Carozzi, V., Meregalli, C., Oggioni, N., Sala, B., Crippa, L., Avezza, F., Forestieri, D., Rotella, G., Zucchetti, M., Cavaletti, G.

“…Purpose Cisplatin is one of the most effective cytotoxic agents in the treatment of solid malignancies, but its use is limited by several side effects. Among…”
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Bortezomib-induced peripheral neurotoxicity in human multiple myeloma-bearing mice by Meregalli, C, Carozzi, V A, Sala, B, Chiorazzi, A, Canta, A, Oggioni, N, Rodriguez-Menendez, V, Ballarini, E, Ceresa, C, Nicolini, G, Crippa, L, Orciani, M, Cavaletti, G, Marmiroli, P

“…The proteasome inhibitor bortezomib is an antineoplastic drug mainly used for the treatment of multiple myeloma (MM). Despite its effectiveness, bortezomib…”
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Neurofilament light chain as disease biomarker in a rodent model of chemotherapy induced peripheral neuropathy by Meregalli, Cristina, Fumagalli, Giulia, Alberti, Paola, Canta, Annalisa, Carozzi, Valentina Alda, Chiorazzi, Alessia, Monza, Laura, Pozzi, Eleonora, Sandelius, Åsa, Blennow, Kaj, Zetterberg, Henrik, Marmiroli, Paola, Cavaletti, Guido

“…The objective of this study is to test the feasibility of using serum neurofilament light chain (NfL) as a disease biomarker in Chemotherapy Induced Peripheral…”
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Neurofilament light chain: a specific serum biomarker of axonal damage severity in rat models of Chemotherapy-Induced Peripheral Neurotoxicity by Meregalli, Cristina, Fumagalli, Giulia, Alberti, Paola, Canta, Annalisa, Chiorazzi, Alessia, Monza, Laura, Pozzi, Eleonora, Carozzi, Valentina Alda, Blennow, Kaj, Zetterberg, Henrik, Cavaletti, Guido, Marmiroli, Paola

“…Chemotherapy-Induced Peripheral Neurotoxicity (CIPN) is a severe and long-lasting side effect of anticancer therapy, which can severely impair patients’…”
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Corrigendum to “Chemotherapy-induced peripheral neuropathy: What do we know about mechanisms?” [Neuroscience Letters 596 (2015) 90–107] by Carozzi, V.A, Canta, A., Chiorazzi, A.

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Age-Related Changes in the Function and Structure of the Peripheral Sensory Pathway in Mice by Canta, A, Chiorazzi, A, Carozzi, V, Meregalli, C, Oggioni, N, Bossi, M, Rodriguez-Menendez, V, Avezza, F, Crippa, L, Lombardi, R, de Vito, G, Piazza, V, Cavaletti, G, Marmiroli, P

“…Abstract This study is aimed at describing the changes occurring in the entire peripheral nervous system (PNS) sensory pathway along a 2-year observation…”
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High-dose intravenous immunoglobulins reduce nerve macrophage infiltration and the severity of bortezomib-induced peripheral neurotoxicity in rats by Meregalli, Cristina, Marjanovic, Ivan, Scali, Carla, Monza, Laura, Spinoni, Nadia, Galliani, Cristina, Brivio, Rinaldo, Chiorazzi, Alessia, Ballarini, Elisa, Rodriguez-Menendez, Virginia, Carozzi, Valentina Alda, Alberti, Paola, Fumagalli, Giulia, Pozzi, Eleonora, Canta, Annalisa, Quartu, Marina, Briani, Chiara, Oggioni, Norberto, Marmiroli, Paola, Cavaletti, Guido

“…Chemotherapy-induced peripheral neurotoxicity (CIPN) is a severe adverse effect in patients receiving antitumor agents, and no effective treatment is…”
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Glutamate Carboxypeptidase Inhibition Reduces the Severity of Chemotherapy-Induced Peripheral Neurotoxicity in Rat by Carozzi, Valentina A., Chiorazzi, Alessia, Canta, Annalisa, Lapidus, Rena G., Slusher, Barbara S., Wozniak, Krystyna M., Cavaletti, Guido

“…Chemotherapy is the most common method to treat cancer. The use of certain antineoplastic drugs, however, is associated with the development of peripheral…”
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Effect of the chronic combined administration of cisplatin and paclitaxel in a rat model of peripheral neurotoxicity by Carozzi, Valentina, Chiorazzi, Alessia, Canta, Annalisa, Oggioni, Norberto, Gilardini, Alessandra, Rodriguez-Menendez, Virginia, Avezza, Federica, Crippa, Luca, Ceresa, Cecilia, Nicolini, Gabriella, Bossi, Mario, Cavaletti, Guido

“…Abstract We have characterised for the first time the general and neurological side effects experienced when using a series of chronic non-lethal cisplatin +…”
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CR4056, a new analgesic I2 ligand, is highly effective against bortezomib-induced painful neuropathy in rats by Meregalli, Cristina, Ceresa, Cecilia, Canta, Annalisa, Carozzi, Valentina Alda, Chiorazzi, Alessia, Sala, Barbara, Oggioni, Norberto, Lanza, Marco, Letari, Ornella, Ferrari, Flora, Avezza, Federica, Marmiroli, Paola, Caselli, Gianfranco, Cavaletti, Guido

“…Although bortezomib (BTZ) is the frontline treatment for multiple myeloma, its clinical use is limited by the occurrence of painful peripheral neuropathy,…”
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Continuous buprenorphine delivery effect in streptozotocine-induced painful diabetic neuropathy in rats by Canta, Annalisa, Chiorazzi, Alessia, Meregalli, Cristina, Carozzi, Valentina, Oggioni, Norberto, Lauria, Giuseppe, Lombardi, Raffaella, Bianchi, Roberto, Porretta-Serapiglia, Carla, Cavaletti, Guido

“…Diabetic peripheral neuropathy (DPN) can induce loss of nociception as well as mechanical hyperalgesia and tactile allodynia. Pharmacological and clinical…”
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