Search Results - "Chiodo, A."
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Current treatment practice and outcomes. Report of the hyponatremia registry
Published in Kidney international (01-07-2015)“…Current management practices for hyponatremia (HN) are incompletely understood. The HN Registry has recorded diagnostic measures, utilization, efficacy, and…”
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2
Diagnosing and Treating the Syndrome of Inappropriate Antidiuretic Hormone Secretion
Published in The American journal of medicine (01-05-2016)“…Abstract Background The syndrome of inappropriate antidiuretic hormone secretion is the most common cause of hyponatremia in clinical practice, but current…”
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3
Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma
Published in Molecular therapy (03-10-2018)“…Dysregulation of the complement system is implicated in neurodegeneration, including human and animal glaucoma. Optic nerve and retinal damage in glaucoma is…”
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4
Management Strategies and Outcomes for Hyponatremia in Cirrhosis in the Hyponatremia Registry
Published in Canadian journal of gastroenterology & hepatology (01-01-2018)“…Aim. Treatment practices and effectiveness in cirrhotic patients with hyponatremia (HN) in the HN Registry were assessed. Methods. Characteristics, treatments,…”
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5
Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human X-linked retinitis pigmentosa
Published in Proceedings of the National Academy of Sciences - PNAS (07-02-2012)“…Hereditary retinal blindness is caused by mutations in genes expressed in photoreceptors or retinal pigment epithelium. Gene therapy in mouse and dog models of…”
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6
ELOVL4-Mediated Production of Very Long-Chain Ceramides Stabilizes Tight Junctions and Prevents Diabetes-Induced Retinal Vascular Permeability
Published in Diabetes (New York, N.Y.) (01-04-2018)“…Tight junctions (TJs) involve close apposition of transmembrane proteins between cells. Although TJ proteins have been studied in detail, the role of lipids is…”
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Short-term decreased post transplant lymphoproliferative disorder risk after kidney transplantation using two novel regimens
Published in Transplant immunology (01-02-2023)“…Belatacept is employed alongside calcineurin inhibitor (CNI) therapy to prevent graft rejection in kidney transplant patients who are Epstein-Barr virus (EBV)…”
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Current Management of Hyponatremia in Acute Heart Failure: A Report From the Hyponatremia Registry for Patients With Euvolemic and Hypervolemic Hyponatremia (HN Registry)
Published in Journal of the American Heart Association (01-08-2017)“…Background Hyponatremia (HN) occurs commonly in patients with acute heart failure and confers a worse prognosis. Current HN treatment varies widely, with no…”
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Inhibitor of apoptosis-stimulating protein of p53 (iASPP) is required for neuronal survival after axonal injury
Published in PloS one (01-04-2014)“…The transcription factor p53 mediates the apoptosis of post-mitotic neurons exposed to a wide range of stress stimuli. The apoptotic activity of p53 is tightly…”
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Recombinant AAV-mediated BEST1 transfer to the retinal pigment epithelium: analysis of serotype-dependent retinal effects
Published in PloS one (15-10-2013)“…Mutations in the BEST1 gene constitute an underlying cause of juvenile macular dystrophies, a group of retinal disorders commonly referred to as…”
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11
Transgene expression of Stanniocalcin-1 provides sustained intraocular pressure reduction by increasing outflow facility
Published in PloS one (31-05-2022)“…Glaucoma is the leading cause of irreversible blindness worldwide. Therapies for glaucoma are directed toward reducing intraocular pressure (IOP), the leading…”
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12
Belatacept-based immunosuppression in practice: A single center experience
Published in Transplant immunology (01-06-2023)“…•Our institutional regimen consisted of tacrolimus, Cellcept and belatacept.•Our unique combination therapy minimized rates of acute rejection and eliminated…”
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AAV-mediated cone rescue in a naturally occurring mouse model of CNGA3-achromatopsia
Published in PloS one (11-04-2012)“…Achromatopsia is a rare autosomal recessive disorder which shows color blindness, severely impaired visual acuity, and extreme sensitivity to bright light…”
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ERK1/2 activation is a therapeutic target in age-related macular degeneration
Published in Proceedings of the National Academy of Sciences - PNAS (21-08-2012)“…Deficient expression of the RNase III DICER1, which leads to the accumulation of cytotoxic Alu RNA, has been implicated in degeneration of the retinal…”
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Kidney transplant surgical director training: Urologists represent a functional alternative to general surgeons
Published in Clinical transplantation (01-08-2021)“…Introduction Kidney transplant (KT) directors are general surgeons or urologists. All KT centers must meet established performance standards. However, it has…”
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Consequences of zygote injection and germline transfer of mutant human mitochondrial DNA in mice
Published in Proceedings of the National Academy of Sciences - PNAS (20-10-2015)“…Considerable evidence supports mutations in mitochondrial genes as the cause of maternally inherited diseases affecting tissues that rely primarily on…”
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The human rhodopsin kinase promoter in an AAV5 vector confers rod- and cone-specific expression in the primate retina
Published in Human gene therapy (01-10-2012)“…Adeno-associated virus (AAV) has proven an effective gene delivery vehicle for the treatment of retinal disease. Ongoing clinical trials using a serotype 2 AAV…”
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Secondary health conditions in individuals aging with SCI: Terminology, concepts and analytic approaches
Published in Spinal cord (01-05-2012)“…Study design: Literature review. Objectives: Utilizing individuals with spinal cord injury (SCI) as a representative population for physical disability, this…”
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Neuropsychiatric Symptoms Predict Functional Status in Alzheimer's Disease
Published in Journal of Alzheimer's disease (01-10-2015)“…Cognitive deficits are presumed to be the primary driver of functional impairment in Alzheimer's disease (AD); however, functional impairment is likely…”
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RD3 gene delivery restores guanylate cyclase localization and rescues photoreceptors in the Rd3 mouse model of Leber congenital amaurosis 12
Published in Human molecular genetics (01-10-2013)“…RD3 is a 23 kDa protein implicated in the stable expression of guanylate cyclase in photoreceptor cells. Truncation mutations are responsible for photoreceptor…”
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