Search Results - "Chiocchia, G"

Effects of a low-dose IL-2 treatment in HLA-B27 transgenic rat model of spondyloarthritis by Araujo, L M, Jouhault, Q, Fert, I, Bouiller, I, Chiocchia, G, Breban, M

“…HLA-B27/human β2m transgenic rats (B27-rats) develop an inflammatory disorder resembling spondyloarthritis (SpA) with dysregulated IL-10/IL-17 production by…”
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Circulating endothelial progenitor cells in systemic sclerosis: association with disease severity by Avouac, J, Juin, F, Wipff, J, Couraud, P O, Chiocchia, G, Kahan, A, Boileau, C, Uzan, G, Allanore, Y

“…Heterogeneous data have been reported regarding the detection and number of circulating endothelial progenitor cells (EPCs) in systemic sclerosis (SSc). We…”
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Targeting the Splicing of mRNA in Autoimmune Diseases: BAFF Inhibition in Sjögren's Syndrome as a Proof of Concept by Roescher, N., Vosters, J.L., Alsaleh, G., Dreyfus, P., Jacques, S., Chiocchia, G., Sibilia, J., Tak, P.P., Chiorini, J.A., Mariette, X., Gottenberg, Jacques-Eric

“…BAFF (B-cell–activating factor of the tumor necrosis factor family), a pivotal cytokine for B-cell activation, is overexpressed by salivary gland (SG)…”
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FADD protein release mirrors the development and aggressiveness of human non-small cell lung cancer by Cimino, Y, Costes, A, Damotte, D, Validire, P, Mistou, S, Cagnard, N, Alifano, M, Régnard, J-F, Chiocchia, G, Sautès-Fridman, C, Tourneur, L

“…Background: The need to unfold the underlying mechanisms of lung cancer aggressiveness, the deadliest cancer in the world, is of prime importance. Because…”
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Evidence of the contribution of the X chromosome to systemic sclerosis susceptibility: Association with the functional IRAK1 196Phe/532Ser haplotype by Dieudé, P., Bouaziz, M., Guedj, M., Riemekasten, G., Airò, P., Müller, M., Cusi, D., Matucci‐Cerinic, M., Melchers, I., Koenig, W., Salvi, E., Wichmann, H. E., Cuomo, G., Hachulla, E., Diot, E., Hunzelmann, N., Caramaschi, P., Mouthon, L., Riccieri, V., Distler, J., Tarner, I., Avouac, J., Meyer, O., Kahan, A., Chiocchia, G., Boileau, C., Allanore, Y.

“…Objective Several autoimmune disorders, including systemic sclerosis (SSc), are characterized by a strong sex bias. To date, it is not known whether genes on…”
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Independent replication establishes the CD247 gene as a genetic systemic sclerosis susceptibility factor by Dieudé, Philippe, Boileau, Catherine, Guedj, Mickael, Avouac, Jerome, Ruiz, Barbara, Hachulla, Eric, Diot, Elisabeth, Cracowski, Jean Luc, Tiev, Kiet, Sibilia, Jean, Mouthon, Luc, Frances, Camille, Amoura, Zahir, Carpentier, Patrick, Cosnes, Anne, Meyer, Olivier, Kahan, Andre, Chiocchia, Gilles, Allanore, Yannick

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DNA microarray allows molecular profiling of rheumatoid arthritis and identification of pathophysiological targets by Devauchelle, V, Marion, S, Cagnard, N, Mistou, S, Falgarone, G, Breban, M, Letourneur, F, Pitaval, A, Alibert, O, Lucchesi, C, Anract, P, Hamadouche, M, Ayral, X, Dougados, M, Gidrol, X, Fournier, C, Chiocchia, G

“…This study was undertaken to evaluate the possibility to obtain a molecular signature of rheumatoid arthritis (RA) comparatively osteoarthritis (OA), and to…”
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High susceptibility to collagen-induced arthritis in mice lacking IFN- gamma receptors by Manoury-Schwartz, B, Chiocchia, G, Bessis, N, Abehsira-Amar, O, Batteux, F, Muller, S, Huang, S, Boissier, MC, Fournier, C

“…Collagen-induced arthritis (CIA), an animal model for rheumatoid arthritis, is induced in DBA/1 (H-2q) mice following immunization with type II collagen (CII)…”
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Lack of association between Tenascin-C gene and spondyloarthritis by Zinovieva, E., Lebrun, N., Letourneur, F., Laurent, F.-X., Said-Nahal, R., Chiocchia, G., Breban, M.

“…Objectives. We previously identified a new susceptibility region linked to SpA in 9q31–34. Tenascin-C (TNC) appears as one of the best positional and…”
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Transgenic Expression of CD95 Ligand on Thyroid Follicular Cells Confers Immune Privilege upon Thyroid Allografts by Tourneur, Lea, Malassagne, Benoit, Batteux, Frederic, Fabre, Monique, Mistou, Sylvie, Lallemand, Eliette, Lores, Patrick, Chiocchia, Gilles

“…Constitutive Fas ligand (FasL) expression by specialized cells in the body participates in the immune privilege status of tissues containing these cells. This…”
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Collagen II-pulsed antigen-presenting cells genetically modified to secrete IL-4 down-regulate collagen-induced arthritis by GUERY, L, CHIOCCHIA, G, BATTEUX, F, BOISSIER, M.-C, FOURNIER, C

“…We explored the possibility that pulsed antigen-presenting cells (APC) provide a model vector system for site-specific delivery of immunosuppressive proteins…”
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Modulation of proinflammatory cytokine production in tumour necrosis factor‐alpha (TNF‐α)‐transgenic mice by treatment with cells engineered to secrete IL‐4, IL‐10 or IL‐13 by BESSIS, N, CHIOCCHIA, G, KOLLIAS, G, MINTY, A, FOURNIER, C, FRADELIZI, D, BOISSIER, M. C

“…TNF‐α is one of the major proinflammatory cytokines involved in the pathogenesis of chronic inflammatory joint disease, in human rheumatoid arthritis as well…”
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Therapy against murine collagen-induced arthritis with T cell receptor V beta-specific antibodies by Chiocchia, G, Boissier, M C, Fournier, C

“…Immunization with native type II collagen (CII) of susceptible strains of mice (H-2q) induces a rheumatoid arthritis-like disease. Collagen-induced arthritis…”
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The Education of the Aerospace Engineers of the 21st Century: a Challenge for Universities by Chiocchia, G., Guglieri, G.

“…The job profile of the aerospace engineers in the industry as well in aviation has undergone substantial changes during the last decades. The classical…”
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HLA–B27 Subtypes Predisposing to Ankylosing Spondylitis Accumulate in an Endoplasmic Reticulum–Derived Compartment Apart From the Peptide‐Loading Complex by Jah, Nadège, Jobart‐Malfait, Aude, Ermoza, Ketia, Noteuil, Aurélie, Chiocchia, Gilles, Breban, Maxime, André, Claudine

“…Objective It was previously shown that HLA–B27 subtypes predisposing to spondyloarthritis (SpA), i.e., B*27:02, B*27:05, and B*27:07, displayed an increased…”
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Angiogenesis in systemic sclerosis: Impaired expression of vascular endothelial growth factor receptor 1 in endothelial progenitor–derived cells under hypoxic conditions by Avouac, J., Wipff, J., Goldman, O., Ruiz, B., Couraud, P. O., Chiocchia, G., Kahan, A., Boileau, C., Uzan, G., Allanore, Y.

“…Objective To assess angiogenesis and explore the expression and regulation of vascular endothelial growth factor (VEGF), VEGF receptor 1 (VEGFR‐1), and…”
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Activation of IFN Pathways and Plasmacytoid Dendritic Cell Recruitment in Target Organs of Primary Sjögren's Syndrome by Gottenberg, Jacques-Eric, Cagnard, Nicolas, Lucchesi, Carlo, Letourneur, Franck, Mistou, Sylvie, Lazure, Thierry, Jacques, Sebastien, Ba, Nathalie, Ittah, Marc, Lepajolec, Christine, Labetoulle, Marc, Ardizzone, Marc, Sibilia, Jean, Fournier, Catherine, Chiocchia, Gilles, Mariette, Xavier

“…Gene expression analysis of target organs might help provide new insights into the pathogenesis of autoimmune diseases. We used global gene expression…”
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The classical NLRP3 inflammasome controls FADD unconventional secretion through microvesicle shedding by Mouasni, Sara, Gonzalez, Virginie, Schmitt, Alain, Bennana, Evangeline, Guillonneau, François, Mistou, Sylvie, Avouac, Jérôme, Ea, Hang Korng, Devauchelle, Valérie, Gottenberg, Jacques-Eric, Chiocchia, Gilles, Tourneur, Léa

“…Fas-associated death domain (FADD) is a key adaptor molecule involved in numerous physiological processes including cell death, proliferation, innate immunity…”
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Quelle place pour les puces à ADN dans les maladies inflammatoires ? by Devauchelle, V., Chiocchia, G.

“…Propos. – La puce à ADN, est une technique de développement relativement récent permettant l'étude des profils d'expression de plusieurs milliers de gènes, au…”
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Effect of catecholamines on deformability of red cells from trout: relative roles of cyclic AMP and cell volume by Chiocchia, G, Motais, R

“…1. In the presence of catecholamine the nucleated red blood cells of trout show a large increase in cell volume as a result of an accumulation of sodium and…”
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