Search Results - "Chintamaneni, Pavan Kumar"

A Design of Experiment (DoE) based approach for development and optimization of nanosuspensions of telmisartan, a BCS class II antihypertensive drug by Bhargav, E., Chaithanya Barghav, G., Padmanabha Reddy, Y., Pavan kumar, Chintamaneni, Ramalingam, P., Haranath, C.

“…Background The present study was aimed to enhance the solubility and dissolution of BCS class II drug, telmisartan (TEM), by nanoformulation approach. Several…”
Get full text

Solid Lipid Nanoparticles vs. Nanostructured Lipid Carriers: A Comparative Review by Viegas, Cláudia, Patrício, Ana B, Prata, João M, Nadhman, Akhtar, Chintamaneni, Pavan Kumar, Fonte, Pedro

“…Solid-lipid nanoparticles and nanostructured lipid carriers are delivery systems for the delivery of drugs and other bioactives used in diagnosis, therapy, and…”
Get full text

Plausible role of combination of Chlorpromazine hydrochloride and Teicoplanin against COVID-19 by Sathyamoorthy, NandhaKumar, Chintamaneni, Pavan Kumar, Chinni, Santhivardhan

Get full text

Quantum Dot loaded BQCA‐Octadecylamine conjugate nanosystems for theranostic applications in Alzheimer’s Disease by Chintamaneni, Pavan Kumar, Krishnamurthy, Praveen Thaggikuppe, Pindiprolu, Saikiran S.S, Sathyamoorthy, NandhaKumar

“…Background Alzheimer’s Disease (AD) is one of the most common types of dementias in the world and is characterized by progressive, irreversible…”
Get full text

Conquering chemoresistance in pancreatic cancer: Exploring novel drug therapies and delivery approaches amidst desmoplasia and hypoxia by Chintamaneni, Pavan Kumar, Pindiprolu, Sai Kiran S.S., Swain, Swati Swagatika, Karri, Veera Venkata Satyanarayana Reddy, Nesamony, Jerry, Chelliah, Selvam, Bhaskaran, Mahendran

“…Pancreatic cancer poses a significant challenge within the field of oncology due to its aggressive behaviour, limited treatment choices, and unfavourable…”
Get full text

DR5 antibody conjugated lipid-based nanocarriers of gamma-secretase inhibitor for the treatment of triple negative breast cancer by Pindiprolu, Sai Kiran S.S., Krishnamurthy, Praveen T., Dev, Chetan, Chintamaneni, Pavan Kumar

“…•DR5 targeted solid lipid nanoparticles have been formulated for effective intracellular of γ-secretase inhibitor.•The anticancer efficacy was studied in…”
Get full text

Cytosolic lipid excess-induced mitochondrial dysfunction is the cause or effect of high fat diet-induced skeletal muscle insulin resistance: a molecular insight by Jana, Baishali Alok, Chintamaneni, Pavan Kumar, Krishnamurthy, Praveen Thaggikuppe, Wadhwani, Ashish, Mohankumar, Suresh Kumar

“…Mitochondria play a central role in the energy homeostasis in eukaryotic cells by generating ATP via oxidative metabolism of nutrients. Excess lipid…”
Get full text

Engineered upconversion nanocarriers for synergistic breast cancer imaging and therapy: Current state of art by Chintamaneni, Pavan Kumar, Nagasen, Dasari, Babu, Katta Chanti, Mourya, Atul, Madan, Jitender, Srinivasarao, Dadi A., Ramachandra, R.K., Santhoshi, P. Madhuri, Pindiprolu, Sai Kiran S.S.

“…Breast cancer is the most common type of cancer in women and is the second leading cause of cancer-related deaths worldwide. Early diagnosis and effective…”
Get full text

Formulation-optimization of solid lipid nanocarrier system of STAT3 inhibitor to improve its activity in triple negative breast cancer cells by Pindiprolu, Sai Kiran S S, Chintamaneni, Pavan Kumar, Krishnamurthy, Praveen T, Ratna Sree Ganapathineedi, Kinnera

“…In the present study, solid lipid nanoparticles (SLNs) have been formulated as a carrier system for effective intracellular delivery of STAT3 inhibitor,…”
Get full text

Novel drug delivery systems of β2 adrenoreceptor agonists to suppress SNCA gene expression and mitochondrial oxidative stress in Parkinson's disease management by Sola, Piyong, Krishnamurthy, Praveen, Chintamaneni, Pavan Kumar, Pindiprolu, Sai Kiran S S, Kumari, Mamta

“…α-synuclein (SNCA), a major component of Lewy body is a pathological hallmark of Parkinson's disease (PD). Mutations in the SNCA gene cause misfolding and…”
Get more information

Phenyl boronic acid-modified lipid nanocarriers of niclosamide for targeting triple-negative breast cancer by SS Pindiprolu, Sai Kiran, Krishnamurthy, Praveen T, Ghanta, Venkata Rao, Chintamaneni, Pavan Kumar

“…To study the active targeting efficacy of phenylboronic acid-modified niclosamide solid lipid nanoparticles (PBA-Niclo-SLN) in triple-negative breast cancer…”
Get full text

Pharmacological targets of breast cancer stem cells: a review by Pindiprolu, Sai Kiran S. S., Krishnamurthy, Praveen T., Chintamaneni, Pavan Kumar

“…Breast cancers contain small population of tumor-initiating cells called breast cancer stem cells (BCSCs), which are spared even after chemotherapy. Recently,…”
Get full text

Polysorbate-80 surface modified nano-stearylamine BQCA conjugate for the management of Alzheimer's disease by Chintamaneni, Pavan Kumar, Krishnamurthy, Praveen Thaggikuppe, Pindiprolu, Sai Kiran S. S

“…Acetylcholinesterase (AChE) inhibitors such as donepezil, galantamine and rivastigmine are used for the management of dementia in Alzheimer's Disease (AD)…”
Get full text

Clustered Regularly Interspaced Short Palindromic Repeats and its Associated Protein- 9: Drug Delivery and Therapeutic Applications by Haranath, Chinthaginjala, Jonnala, Rachana, Bhargav, Eranti, Ahad, Hindustan Abdul, Chintamaneni, Pavan Kumar

“…Genomic editing, which involves modifying genetic DNA at a specific target site, is now being sought by scientists all over the world in a variety of domains…”
Get full text

From nature's bounty to drug discovery: Leveraging phytochemicals and molecular approaches to combat multi-drug-resistant (MDR) tuberculosis by Nalam, Sarveswara Mounik, Chintamaneni, Pavan Kumar, Saxena Pal, Rashmi, Chaitanya, M.V.N.L., Kumar Singh, Sachin, Saranya, P., Arora, Smriti, Sharma, Sarika, Pandey, Pratibha, Mazumder, Avijit, Babu, Ravindra, Amoateng, Patrick, Singh, Amandeep

“…A large number of people annually lose their lives to tuberculosis (TB), which is an age-old disease caused by the Mycobacterium tuberculosis. The global…”
Get full text

Possible role of PPAR-γ and COX-2 receptor modulators in the treatment of Non-Small Cell lung carcinoma by Ravi Kiran Ammu, V.V.V., Garikapati, Kusuma Kumari, Krishnamurthy, Praveen T., Chintamaneni, Pavan Kumar, Pindiprolu, Sai Kiran S.S.

“…Non-Small Cell lung cancer (NSCLC) accounts for 85% of total lung cancers worldwide, affecting more than 1.5 million people every year. Recent studies reported…”
Get full text

Type-II endometrial cancer: role of adipokines by Garikapati, Kusuma Kumari, Ammu, V. V. V. Ravi Kiran, Krishnamurthy, Praveen T., Chintamaneni, Pavan Kumar, Pindiprolu, Sai Kiran S. S.

“…Background Type-II endometrial cancer is an estrogen independent and one of the most lethal types of cancer having poor prognosis. Adipokines play a crucial…”
Get full text

Surface modified nano-lipid drug conjugates of positive allosteric modulators of M1 muscarinic acetylcholine receptor for the treatment of Alzheimer’s disease by Chintamaneni, Pavan Kumar, Krishnamurthy, Praveen T, Rao, Pachava Vengal, Sai Kiran, Pindiprolu SS

“…Abstract Acetyl Cholinesterase (AChE) inhibitors such as Donepezil, Rivastigmine and Galantamine are approved by US-FDA as first line drugs to treat the…”
Get full text

An effective treatment approach of DPP-IV inhibitor encapsulated polymeric nanoparticles conjugated with anti-CD-4 mAb for type 1 diabetes by Thondawada, Mahesh, Wadhwani, Ashish Devidas, S Palanisamy, Dhanabal, Rathore, Hanumant Singh, Gupta, Ramesh C, Chintamaneni, Pavan Kumar, Samanta, Malay K, Dubala, Anil, Varma, Sameer, Krishnamurthy, Praveen T, Gowthamarajan, Kuppusamy

“…Nanotechnology based biomedical approaches and surface modification techniques made it easier for targeting specific site and improving the treatment efficacy…”
Get full text

Possible role of Thiazolidinedione in the management of Type-II Endometrial Cancer by Garikapati, Kusuma Kumari, Ammu, V.V.V. Ravi Kiran, Krishnamurthy, Praveen T., Chintamaneni, Pavan Kumar, Pindiprolu, Sai kiran S.S.

“…Type-II Endometrial Cancer (EMC) is one of the most common types of gynaecological cancer affecting more than 2.7 million people worldwide. Clinical evidence…”
Get full text