Search Results - "Chintakrindi, Anand S."

A Computational Model for Docking of Noncompetitive Neuraminidase Inhibitors and Probing their Binding Interactions with Neuraminidase of Influenza Virus H5N1 by Chintakrindi, Anand S, Martis, Elvis A F, Gohil, Devanshi J, Kothari, Sweta T, Chowdhary, Abhay S, Coutinho, Evans C, Kanyalkar, Meena A

“…With cases of emergence of drug resistance to the current competitive inhibitors of neuraminidase (NA) such as oseltamivir and zanamavir, there is a present…”
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Design, synthesis and biological evaluation of substituted flavones and aurones as potential anti-influenza agents by Chintakrindi, Anand S., Gohil, Devanshi J., Chowdhary, Abhay S., Kanyalkar, Meena A.

“…[Display omitted] •Substituted flavones and aurones are docked in 150-cavity and 430-cavity of H1N1 neuraminidase.•Substituted flavones and aurones reduce H1N1…”
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Structure-aided drug development of potential neuraminidase inhibitors against pandemic H1N1 exploring alternate binding mechanism by Malbari, Khushboo D., Chintakrindi, Anand S., Ganji, Lata R., Gohil, Devanshi J., Kothari, Sweta T., Joshi, Mamata V., Kanyalkar, Meena A.

“…The rate of mutability of pathogenic H1N1 influenza virus is a threat. The emergence of drug resistance to the current competitive inhibitors of neuraminidase,…”
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Design, synthesis and evaluation of chalcones as H1N1 Neuraminidase inhibitors by Chintakrindi, Anand S., Gohil, Devanshi J., Kothari, Sweta T., Chowdhary, Abhay S., Kanyalkar, Meena A.

“…A series of chalcone derivatives ( 1a – 2i ) were designed based on isoliquiritigenin (the most active natural chalcone non-competitive neuraminidase (NA)…”
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De novo design of 7-aminocoumarin derivatives as novel falcipain-3 inhibitors by Chintakrindi, Anand S., Shaikh, Mushtaque S., Coutinho, Evans C.

“…The availability of the crystal structure of falcipain-3, knowledge of the peptides carrying the 7-aminocoumarin moiety as falcipain-3 ligands/substrates, and…”
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Drug susceptibility of influenza A/H3N2 strains co-circulating during 2009 influenza pandemic: First report from Mumbai by Gohil, Devanshi J., Kothari, Sweta T., Shinde, Pramod S., Chintakrindi, Anand S., Meharunkar, Rhuta, Warke, Rajas V., Kanyalkar, Meena A., Chowdhary, Abhay S., Deshmukh, Ranjana A.

“…•Influenza A/H3N2 isolates harbor mutations known to confer resistance to amantadine.•No know mutations conferring resistance to neuraminidase inhibitors were…”
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