Search Results - "Chinnathambi, Arunachalam"

Zinc nanoparticles green-synthesized by Alhagi maurorum leaf aqueous extract: Chemical characterization and cytotoxicity, antioxidant, and anti-osteosarcoma effects by Chinnathambi, Arunachalam, Alahmadi, Tahani Awad

“…In this study, zinc oxide nanoparticles (ZnONPs) were synthesized in an aqueous medium using the plant extract as stabilizing and reducing agents. The…”
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Oleuropein induces apoptosis via abrogating NF‐κB activation cascade in estrogen receptor–negative breast cancer cells by Liu, Lian, Ahn, Kwang Seok, Shanmugam, Muthu K, Wang, Hong, Shen, Hongyuan, Arfuso, Frank, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Chang, Yung, Sethi, Gautam, Tang, Feng Ru

“…Oleuropein is one of the most abundant phenolic compounds found in olives. Epidemiological studies have indicated that an increasing intake of olive oil can…”
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Plumbagin protects the myocardial damage by modulating the cardiac biomarkers, antioxidants, and apoptosis signaling in the doxorubicin‐induced cardiotoxicity in rats by Li, Zhe, Chinnathambi, Arunachalam, Ali Alharbi, Sulaiman, Yin, Fuyu

“…Cardiovascular disease created enormous health and economic burdens worldwide, which is responsible for the highest mobility and mortality that results in…”
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Fabrication of folic acid-embedded aminated drug encapsulated zeolitic imidazolate framework as promising drug delivery system for lung cancer by Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Ramar, Mohankumar, Arulselvan, Palanisamy, Muthusami, Sridhar

“…A novel pH-responsive drug carrier for the delivery of specific Docetaxel (DTX) administration is developed based on a zeolitic imidazolate framework (ZIF-8)…”
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Green synthesis and chemical characterization of a novel anti-human pancreatic cancer supplement by silver nanoparticles containing Zingiber officinale leaf aqueous extract by Wang, Yunjian, Chinnathambi, Arunachalam, Nasif, Omaima, Alharbi, Sulaiman Ali

“…In recent years, silver nanoparticles (AgNPs) have been used as key chemotherapeutic drugs to treat various cancers like prostate, breast, ovarian, and blood…”
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LDL cholesterol promotes the proliferation of prostate and pancreatic cancer cells by activating the STAT3 pathway by Jung, Young Yun, Ko, Jeong‐Hyeon, Um, Jae‐Young, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Sethi, Gautam, Ahn, Kwang Seok

“…Hypercholesterolemia has been found to be closely linked with a significant increase in both cancer incidence and mortality. However, the exact correlation…”
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Biogenesis of copper nanoparticles (Cu-NPs) using leaf extract of Allium noeanum, antioxidant and in-vitro cytotoxicity by Chinnathambi, Arunachalam, Awad Alahmadi, Tahani, Ali Alharbi, Sulaiman

“…In this research, we formulated new chemotherapeutic copper nanoparticles (Cu NPs) containing Allium noeanum Reut. ex Regel leaf for treating human endometrial…”
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Anti-cancer potential of selenium-chitosan-polyethylene glycol-carvacrol nanocomposites in multiple myeloma U266 cells by Zhang, Haixi, Zhao, Jie, Chinnathambi, Arunachalam, Meganathan, Velmurugan, Gu, Xuezhong

“…Multiple myeloma (MM) is an incurable cancer that is characterized by malignant plasma cell proliferation. Approximately 10% of all blood cancers are MM, and…”
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The multifaceted role of curcumin in cancer prevention and treatment by Shanmugam, Muthu K, Rane, Grishma, Kanchi, Madhu Mathi, Arfuso, Frank, Chinnathambi, Arunachalam, Zayed, M E, Alharbi, Sulaiman Ali, Tan, Benny K H, Kumar, Alan Prem, Sethi, Gautam

“…Despite significant advances in treatment modalities over the last decade, neither the incidence of the disease nor the mortality due to cancer has altered in…”
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Phyllanthin prevents diethylnitrosamine (DEN) induced liver carcinogenesis in rats and induces apoptotic cell death in HepG2 cells by You, Yulai, Zhu, Fengfeng, Li, Zhenhuan, Zhang, LingFeng, Xie, Yu, Chinnathambi, Arunachalam, Alahmadi, Tahani Awad, Lu, Bei

“…Liver cancer is a critical clinical condition with augmented malignancy, rapid progression, and poor prognosis. Liver cancer often initiates as fibrosis,…”
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Identification of protocatechuic acid as a novel blocker of epithelial‐to‐mesenchymal transition in lung tumor cells by Yang, Min Hee, Baek, Seung Ho, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Ahn, Kwang Seok

“…Protocatechuic acid (PA) is widely distributed and commonly occurring natural compound that can exert antioxidant, anti‐inflammatory, as well as anti‐cancer…”
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Dual drug co‐encapsulation of bevacizumab and pemetrexed clocked polymeric nanoparticles improves antiproliferative activity and apoptosis induction in liver cancer cells by Ganesan, Subbulakshmi, Upadhye, Vijay J., Aulakh, Damanjeet, Bishnoi, Sunita, Chinnathambi, Arunachalam, Alahmadi, Tahani Awad, Abudoleh, Suha Mujahed, Arulselvan, Palanisamy, Thangavelu, Indumathi

“…Nanoparticle (NP) enabled approaches have been employed for chemotherapeutic administration due to their capacity to regulate drug release and reduce side…”
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D-Carvone inhibit cerebral ischemia/reperfusion induced inflammatory response TLR4/NLRP3 signaling pathway by Dai, Mengyuan, Wu, Lixiu, Yu, Kunqiang, Xu, Ri, Wei, Yanbin, Chinnathambi, Arunachalam, Alahmadi, Tahani Awad, Zhou, Minya

“…To explore the present treatment strategies for ischemic stroke lowered by ischemia-reperfusion (I/R) injury, to hypothesize the effect of d-Carvone on…”
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Fangchinoline targets epithelial–mesenchymal transition process by modulating activation of multiple cell‐signaling pathways by Jung, Young Y., Chinnathambi, Arunachalam, Alahmadi, Tahani A., Alharbi, Sulaiman A., Kumar, Alan P., Sethi, Gautam, Ahn, Kwang S.

“…Epithelial–mesenchymal transition (EMT) is a key process, which can promote the transition of tumor cells into other organs by weakening the cell‐cell…”
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Thymoquinone Inhibits Bone Metastasis of Breast Cancer Cells Through Abrogation of the CXCR4 Signaling Axis by Shanmugam, Muthu K, Ahn, Kwang Seok, Hsu, Annie, Woo, Chern Chiuh, Yuan, Yi, Tan, Kwong Huat Benny, Chinnathambi, Arunachalam, Alahmadi, Tahani Awad, Alharbi, Sulaiman Ali, Koh, Angele Pei Fern, Arfuso, Frank, Huang, Ruby Yun-Ju, Lim, Lina H K, Sethi, Gautam, Kumar, Alan Prem

“…Overexpression of chemokine receptor type 4 (CXCR4) has been found to be associated with increased cell proliferation, metastasis and also act as an indicator…”
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Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells by Baek, Seung Ho, Ko, Jeong-Hyeon, Lee, Hanwool, Jung, Jinhong, Kong, Moonkyoo, Lee, Jung-woo, Lee, Junhee, Chinnathambi, Arunachalam, Zayed, ME, Alharbi, Sulaiman Ali, Lee, Seok-Geun, Shim, Bum Sang, Sethi, Gautam, Kim, Sung-Hoon, Yang, Woong Mo, Um, Jae-Young, Ahn, Kwang Seok

“…Signal transducer and activator of transcription 3 (STAT3) is persistently activated in squamous cell carcinoma of the head and neck (SCCHN) and can cause…”
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Cycloastragenol can negate constitutive STAT3 activation and promote paclitaxel-induced apoptosis in human gastric cancer cells by Hwang, Sun Tae, Kim, Chulwon, Lee, Jong Hyun, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Shair, Omar H.M., Sethi, Gautam, Ahn, Kwang Seok

“…Cycloastragenol (CAG), a triterpene aglycone is commonly prescribed for treating hypertension, cardiovascular disease, diabetic nephropathy, viral hepatitis,…”
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Essential oils as an effective alternative for the treatment of COVID-19: Molecular interaction analysis of protease (Mpro) with pharmacokinetics and toxicological properties by Panikar, Sukanya, Shoba, Gunasekaran, Arun, Muthukrishnan, Sahayarayan, Jesudass Joseph, Usha Raja Nanthini, A., Chinnathambi, Arunachalam, Alharbi, Sulaiman A., Nasif, Omaima, Kim, Hak-Jae

“…The current health concern to the entire world is the chronic respiratory disease caused by coronavirus 2 (COVID-19). A specific treatment or proper therapy is…”
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Role of novel histone modifications in cancer by Shanmugam, Muthu K, Arfuso, Frank, Arumugam, Surendar, Chinnathambi, Arunachalam, Jinsong, Bian, Warrier, Sudha, Wang, Ling Zhi, Kumar, Alan Prem, Ahn, Kwang Seok, Sethi, Gautam, Lakshmanan, Manikandan

“…Oncogenesis is a multistep process mediated by a variety of factors including epigenetic modifications. Global epigenetic post-translational modifications have…”
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Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway by Mohan, Chakrabhavi Dhananjaya, Srinivasa, V, Rangappa, Shobith, Mervin, Lewis, Mohan, Surender, Paricharak, Shardul, Baday, Sefer, Li, Feng, Shanmugam, Muthu K, Chinnathambi, Arunachalam, Zayed, M E, Alharbi, Sulaiman Ali, Bender, Andreas, Sethi, Gautam, Basappa, Rangappa, Kanchugarakoppal S

“…Overactivation of PI3K/Akt/mTOR is linked with carcinogenesis and serves a potential molecular therapeutic target in treatment of various cancers. Herein, we…”
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