Search Results - "Chinnappan, Raja"

Aptamers: Potential Diagnostic and Therapeutic Agents for Blood Diseases by Aljohani, Maher M, Cialla-May, Dana, Popp, Jürgen, Chinnappan, Raja, Al-Kattan, Khaled, Zourob, Mohammed

“…Aptamers are RNA/DNA oligonucleotide molecules that specifically bind to a targeted complementary molecule. As potential recognition elements with promising…”
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A rapid colorimetric immunoassay for the detection of pathogenic bacteria on poultry processing plants using cotton swabs and nanobeads by Alamer, Saleh, Eissa, Shimaa, Chinnappan, Raja, Zourob, Mohammed

“…The work describes a simple cotton swab-based colorimetric immunoassay as a rapid screening tool for pathogenic bacteria on poultry processing plants. This…”
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Semilunar sign of cornea: A multimodal analysis of the posterior corneal opacity in non-infectious anterior scleritis by Kumar, Dhivya, Agarwal, Amar, Chandrasekar, Radhika, Chinnappan, Raja

“…Purpose: To analyze the morphological outcomes of the posterior corneal opacity or "semilunar sign" in noninfectious anterior scleritis using multimodal…”
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Long period grating based biosensor for the detection of Escherichia coli bacteria by Tripathi, Saurabh Mani, Bock, Wojtek J., Mikulic, Predrag, Chinnappan, Raja, Ng, Andy, Tolba, Mona, Zourob, Mohammed

“…▸ A stable, label-free, bacteriophage-based detection of E. coli using ultra sensitive long-period gratings is demonstrated. ▸ E. coli binding by covalently…”
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Probing high-affinity aptamer binding region and development of aptasensor platform for the detection of cylindrospermopsin by Chinnappan, Raja, AlZabn, Razan, Fataftah, Amjad K., Alhoshani, Ali, Zourob, Mohammed

“…Cylindrospermopsin (CYN) is one of the most concerning cyanotoxins due to its potential toxicity and spreading to various environments including drinking…”
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Determination of minimal sequence for zearalenone aptamer by computational docking and application on an indirect competitive electrochemical aptasensor by Azri, Farah Asilah, Selamat, Jinap, Sukor, Rashidah, Yusof, Nor Azah, Raston, Nurul Hanun Ahmad, Eissa, Shimaa, Zourob, Mohammed, Chinnappan, Raja

“…Aptamers are short single-stranded oligonucleotides (either DNA or RNA) that can fold into well-defined three-dimensional (3D) spatial structures which enable…”
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Electrochemical determination of zearalenone using a label-free competitive aptasensor by Azri, Farah Asilah, Eissa, Shimaa, Zourob, Mohammed, Chinnappan, Raja, Sukor, Rashidah, Yusof, Nor Azah, Raston, Nurul Hanun Ahmad, Alhoshani, Ali, Jinap, Selamat

“…An electrochemical aptasensor is described for determination of the phytohormone of zearalenone (ZEA). The gold electrode was modified with ZEA via covalent…”
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Peptide substrate screening for the diagnosis of SARS-CoV-2 using fluorescence resonance energy transfer (FRET) assay by Alhadrami, Hani A., Hassan, Ahmed M., Chinnappan, Raja, Al-Hadrami, Hind, Abdulaal, Wesam H., Azhar, Esam I., Zourob, Mohammed

“…The novel corona (SARS-CoV-2) virus causes a global pandemic, which motivates researchers to develop reliable and effective methods for screening and detection…”
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Exploring the Utility of ssDNA Aptamers Directed against Snake Venom Toxins as New Therapeutics for Snakebite Envenoming by Alomran, Nessrin, Chinnappan, Raja, Alsolaiss, Jaffer, Casewell, Nicholas R, Zourob, Mohammed

“…Snakebite is a neglected tropical disease that causes considerable death and disability in the tropical world. Although snakebite can cause a variety of…”
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Isolation and Detection of Exosomal Mir210 Using Carbon Nanomaterial-Coated Magnetic Beads by Chinnappan, Raja, Ramadan, Qasem, Zourob, Mohammed

“…MicroRNAs (miRNAs) are short non-coding RNAs that are found in various cellular compartments and play an important role in regulating gene expression…”
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Aptasensors Are Conjectured as Promising ALT and AST Diagnostic Tools for the Early Diagnosis of Acute Liver Injury by Chinnappan, Raja, Mir, Tanveer Ahmad, Alsalameh, Sulaiman, Makhzoum, Tariq, Adeeb, Salma, Al-Kattan, Khaled, Yaqinuddin, Ahmed

“…Abnormal levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in human serum are the most sensitive indicator of hepatocellular…”
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Anti-VCAM-1 and Anti-IL4Rα Aptamer-Conjugated Super Paramagnetic Iron Oxide Nanoparticles for Enhanced Breast Cancer Diagnosis and Therapy by Chinnappan, Raja, Al Faraj, Achraf, Abdel Rahman, Anas M, Abu-Salah, Khalid M, Mouffouk, Fouzi, Zourob, Mohammed

“…The surface protein overexpressed on cancer cells can be used as biomarkers for early detection of specific diseases. Anti-VCAM-1 and anti-IL4Rα DNA aptamers…”
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Advances in Biosensing Technologies for Diagnosis of COVID-19 by Alsalameh, Sulaiman, Alnajjar, Khalid, Makhzoum, Tariq, Al Eman, Noor, Shakir, Ismail, Mir, Tanveer Ahmad, Alkattan, Khaled, Chinnappan, Raja, Yaqinuddin, Ahmed

“…The COVID-19 pandemic has severely impacted normal human life worldwide. Due to its rapid community spread and high mortality statistics, the development of…”
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Folding of the lysine riboswitch: importance of peripheral elements for transcriptional regulation by Blouin, Simon, Chinnappan, Raja, Lafontaine, Daniel A

“…The Bacillus subtilis lysC lysine riboswitch modulates its own gene expression upon lysine binding through a transcription attenuation mechanism. The…”
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A Hypothetical Approach to Concentrate Microorganisms from Human Urine Samples Using Paper-Based Adsorbents for Point-of-Care Molecular Assays by Uttam, Isha, Sudarsan, Sujesh, Ray, Rohitraj, Chinnappan, Raja, Yaqinuddin, Ahmed, Al-Kattan, Khaled, Mani, Naresh Kumar

“…This hypothesis demonstrates that the efficiency of loop-mediated isothermal amplification (LAMP) for nucleic acid detection can be positively influenced by…”
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Low-Cost Point-of-Care Monitoring of ALT and AST Is Promising for Faster Decision Making and Diagnosis of Acute Liver Injury by Chinnappan, Raja, Mir, Tanveer Ahmad, Alsalameh, Suliman, Makhzoum, Tariq, Alzhrani, Alaa, Al-Kattan, Khaled, Yaqinuddin, Ahmed

“…Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are important liver enzymes in clinical settings. Their levels are known to be elevated in…”
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Biosensing of Alpha-Fetoprotein: A Key Direction toward the Early Detection and Management of Hepatocellular Carcinoma by Ramachandran, Lohit, Abul Rub, Farah, Hajja, Amro, Alodhaibi, Ibrahim, Arai, Momo, Alfuwais, Mohammed, Makhzoum, Tariq, Yaqinuddin, Ahmed, Al-Kattan, Khaled, Assiri, Abdullah M, Broering, Dieter C, Chinnappan, Raja, Mir, Tanveer Ahmad, Mani, Naresh Kumar

“…Hepatocellular carcinoma (HCC) is currently one of the most prevalent cancers worldwide. Associated risk factors include, but are not limited to, cirrhosis and…”
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Emerging role of exosomal microRNA in liver cancer in the era of precision medicine; potential and challenges by El Hayek, Tarek, Alnaser-Almusa, Osama Abdulwahab, Alsalameh, Sulaiman Mamoun, Alhalabi, Maya Taofik, Sabbah, Ahmad Nedal, Alshehri, Eman Abdullah, Mir, Tanveer Ahmad, Mani, Naresh Kumar, Al-Kattan, Khaled, Chinnappan, Raja, Yaqinuddin, Ahmed

“…Exosomal microRNAs (miRNAs) have great potential in the fight against hepatocellular carcinoma (HCC), the fourth most common cause of cancer-related death…”
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Rapid Colorimetric Quantita2tive Portable Platform for Detection of Brucella melitensis Based on a Fluorescence Resonance Energy Transfer Assay and Nanomagnetic Particles by Alhogail, Sahar, Chinnappan, Raja, Suaifan, Ghadeer A.R.Y., Abu-Salah, Khalid M., Al-Kattan, Khaled, Cialla-May, Dana, Jürgen, Popp, Zourob, Mohammed M.

“…Brucellosis is a bacterial zoonotic disease that requires major attention for both health and financial facilities in many parts of the world including the…”
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Molecular engineering of a fluorescent probe for highly efficient detection of human serum albumin in biological fluid by Chinnappan, Raja, Mir, Tanveer Ahmad, Easwaramoorthi, Shanmugam, Sunil, Gopika, Feba, Ancy, Kanagasabai, Balamurugan, Wani, Shadil Ibrahim, Sandouka, Maram N., Alzhrani, Alaa, Devanesan, Sandhanasamy, AlSalhi, Mohamad S., Mani, Naresh Kumar, Al-Kattan, Wael, Yaqinuddin, Ahmed, Assiri, Abdullah M., Broering, Dieter C.

“…Human serum albumin (HSA) is synthesized by the liver, accounting for 60 % of total plasma protein in vertebrates' blood. It is the most predominant…”
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