Search Results - "Chinnakannan, Senthil k"

Morbillivirus v proteins exhibit multiple mechanisms to block type 1 and type 2 interferon signalling pathways by Chinnakannan, Senthil K, Nanda, Sambit K, Baron, Michael D

“…Morbilliviruses form a closely related group of pathogenic viruses which encode three non-structural proteins V, W and C in their P gene. Previous studies with…”
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The Design and Development of a Multi-HBV Antigen Encoded in Chimpanzee Adenoviral and Modified Vaccinia Ankara Viral Vectors; A Novel Therapeutic Vaccine Strategy against HBV by Chinnakannan, Senthil K, Cargill, Tamsin N, Donnison, Timothy A, Ansari, M Azim, Sebastian, Sarah, Lee, Lian Ni, Hutchings, Claire, Klenerman, Paul, Maini, Mala K, Evans, Tom, Barnes, Eleanor

“…Chronic hepatitis B virus (HBV) infection affects 257 million people globally. Current therapies suppress HBV but viral rebound occurs on cessation of therapy;…”
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Investigation of IRES Insertion into the Genome of Recombinant MVA as a Translation Enhancer in the Context of Transcript Decapping by Alharbi, Naif Khalaf, Chinnakannan, Senthil K, Gilbert, Sarah C, Draper, Simon J

“…Recombinant modified vaccinia virus Ankara (MVA) has been used to deliver vaccine candidate antigens against infectious diseases and cancer. MVA is a potent…”
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NK cells limit therapeutic vaccine-induced CD8 + T cell immunity in a PD-L1-dependent manner by Diniz, Mariana O, Schurich, Anna, Chinnakannan, Senthil K, Duriez, Marion, Stegmann, Kerstin A, Davies, Jessica, Kucykowicz, Stephanie, Suveizdyte, Kornelija, Amin, Oliver E, Alcock, Frances, Cargill, Tamsin, Barnes, Eleanor, Maini, Mala K

“…A better understanding of mechanisms that regulate CD8 T cell responses to therapeutic vaccines is needed to develop approaches to enhance vaccine efficacy for…”
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Antibody testing for COVID-19: A report from the National COVID Scientific Advisory Panel by Adams, Emily R, Ainsworth, Mark, Anand, Rekha, Andersson, Monique I, Auckland, Kathryn, Baillie, J Kenneth, Barnes, Eleanor, Beer, Sally, Bell, John I, Berry, Tamsin, Bibi, Sagida, Carroll, Miles, Chinnakannan, Senthil K, Clutterbuck, Elizabeth, Cornall, Richard J, Crook, Derrick W, de Silva, Thushan, Dejnirattisai, Wanwisa, Dingle, Kate E, Dold, Christina, Espinosa, Alexis, Eyre, David W, Farmer, Helen, Fernandez Mendoza, Maria, Georgiou, Dominique, Hoosdally, Sarah J, Hunter, Alastair, Jefferey, Katie, Kelly, Dominic F, Klenerman, Paul, Knight, Julian, Knowles, Clarice, Kwok, Andrew J, Leuschner, Ullrich, Levin, Robert, Liu, Chang, López-Camacho, César, Martinez, Jose, Matthews, Philippa C, McGivern, Hannah, Mentzer, Alexander J, Milton, Jonathan, Mongkolsapaya, Juthathip, Moore, Shona C, Oliveira, Marta S, Pereira, Fiona, Perez, Elena, Peto, Timothy, Ploeg, Rutger J, Pollard, Andrew, Prince, Tessa, Roberts, David J, Rudkin, Justine K, Sanchez, Veronica, Screaton, Gavin R, Semple, Malcolm G, Slon-Campos, Jose, Skelly, Donal T, Smith, Elliot Nathan, Sobrinodiaz, Alberto, Staves, Julie, Stuart, David I, Supasa, Piyada, Surik, Tomas, Thraves, Hannah, Tsang, Pat, Turtle, Lance, Walker, A Sarah, Wang, Beibei, Washington, Charlotte, Watkins, Nicholas, Whitehouse, James

“…The COVID-19 pandemic caused >1 million infections during January-March 2020. There is an urgent need for reliable antibody detection approaches to support…”
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Different functions of the common P/V/W and V-specific domains of rinderpest virus V protein in blocking IFN signalling by Chinnakannan, Senthil K, Holzer, Barbara, Bernardo, Beatriz Sanz, Nanda, Sambit K, Baron, Michael D

“…The V proteins of paramyxoviruses are composed of two evolutionarily distinct domains, the N-terminal 75 % being common to the viral P, V and W proteins, and…”
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Enhancing cellular immunogenicity of MVA-vectored vaccines by utilizing the F11L endogenous promoter by Alharbi, Naif Khalaf, Spencer, Alexandra J, Salman, Ahmed M, Tully, Claire M, Chinnakannan, Senthil k, Lambe, Teresa, Yamaguchi, Yuko, Morris, Susan J, Orubu, Toritse, Draper, Simon J, Hill, Adrian V.S, Gilbert, Sarah C

“…Highlights • This study presents the effect of stronger promoters on MVA immunogenicity. • F11 promoter (pF11) enhanced in vivo transgene expression and…”
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Investigation of IRES Insertion into the Genome of Recombinant MVA as a Translation Enhancer in the Context of Transcript Decapping: e0127978 by Alharbi, Naif Khalaf, Chinnakannan, Senthil K, Gilbert, Sarah C, Draper, Simon J

“…Recombinant modified vaccinia virus Ankara (MVA) has been used to deliver vaccine candidate antigens against infectious diseases and cancer. MVA is a potent…”
Get full text