Search Results - "Ching, R."
-
1
Structural brain imaging studies offer clues about the effects of the shared genetic etiology among neuropsychiatric disorders
Published in Molecular psychiatry (01-06-2021)“…Genomewide association studies have found significant genetic correlations among many neuropsychiatric disorders. In contrast, we know much less about the…”
Get full text
Journal Article -
2
Subcortical shape alterations in major depressive disorder: Findings from the ENIGMA major depressive disorder working group
Published in Human brain mapping (01-01-2022)“…Alterations in regional subcortical brain volumes have been investigated as part of the efforts of an international consortium, ENIGMA, to identify reliable…”
Get full text
Journal Article -
3
Unbiased tensor-based morphometry: Improved robustness and sample size estimates for Alzheimer's disease clinical trials
Published in NeuroImage (Orlando, Fla.) (01-02-2013)“…Various neuroimaging measures are being evaluated for tracking Alzheimer's disease (AD) progression in therapeutic trials, including measures of structural…”
Get full text
Journal Article -
4
Effects of gene dosage and development on subcortical nuclei volumes in individuals with 22q11.2 copy number variations
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2024)“…The 22q11.2 locus contains genes critical for brain development. Reciprocal Copy Number Variations (CNVs) at this locus impact risk for neurodevelopmental and…”
Get full text
Journal Article -
5
Longitudinal trajectories of cortical development in 22q11.2 copy number variants and typically developing controls
Published in Molecular psychiatry (01-10-2022)“…Probing naturally-occurring, reciprocal genomic copy number variations (CNVs) may help us understand mechanisms that underlie deviations from typical brain…”
Get full text
Journal Article -
6
Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study
Published in Molecular psychiatry (01-11-2020)“…22q11.2 deletion syndrome (22q11DS)—a neurodevelopmental condition caused by a hemizygous deletion on chromosome 22—is associated with an elevated risk of…”
Get full text
Journal Article -
7
Local molecular and global connectomic contributions to cross-disorder cortical abnormalities
Published in Nature communications (10-08-2022)“…Numerous brain disorders demonstrate structural brain abnormalities, which are thought to arise from molecular perturbations or connectome miswiring. The…”
Get full text
Journal Article -
8
Site effects how-to and when: An overview of retrospective techniques to accommodate site effects in multi-site neuroimaging analyses
Published in Frontiers in neurology (31-10-2022)“…Site differences, or systematic differences in feature distributions across multiple data-acquisition sites, are a known source of heterogeneity that may…”
Get full text
Journal Article -
9
Cross disorder comparisons of brain structure in schizophrenia, bipolar disorder, major depressive disorder, and 22q11.2 deletion syndrome: A review of ENIGMA findings
Published in Psychiatry and clinical neurosciences (01-05-2022)“…This review compares the main brain abnormalities in schizophrenia (SZ), bipolar disorder (BD), major depressive disorder (MDD), and 22q11.2 Deletion Syndrome…”
Get full text
Journal Article -
10
Whole body vibration exposures in metropolitan bus drivers: A comparison of three seats
Published in Journal of sound and vibration (04-01-2010)“…Using a repeated measures study design, three different seats were evaluated as 12 metropolitan bus drivers drove a standardized test route including city…”
Get full text
Journal Article -
11
Incidence of Pneumocystis Pneumonia in Immunocompromised Patients without Human Immunodeficiency Virus on Intravenous Pentamidine Prophylaxis: A Systematic Review and Meta-Analysis
Published in Journal of fungi (Basel) (25-03-2023)“…Trimethoprim-sulfamethoxazole (TMP-SMX) is a first-line pneumonia (PCP) prophylaxis agent, but monthly intravenous pentamidine (IVP) is used in…”
Get full text
Journal Article -
12
Mapping 22q11.2 Gene Dosage Effects on Brain Morphometry
Published in The Journal of neuroscience (28-06-2017)“…Reciprocal chromosomal rearrangements at the 22q11.2 locus are associated with elevated risk of neurodevelopmental disorders. The 22q11.2 deletion confers the…”
Get full text
Journal Article -
13
Effects of Big Data Analytics on Sustainable Manufacturing: A Comparative Study Analysis
Published in Chinese journal of urban and environmental studies (Print) (01-12-2022)“…Application of big data analytics (BDA) is seen in various disciplines within an organization to predict trends, explore opportunities and monitor performance…”
Get full text
Journal Article -
14
Multiscale neural gradients reflect transdiagnostic effects of major psychiatric conditions on cortical morphology
Published in Communications biology (27-09-2022)“…It is increasingly recognized that multiple psychiatric conditions are underpinned by shared neural pathways, affecting similar brain systems. Here, we carried…”
Get full text
Journal Article -
15
Medication for opioid use disorder at hospital discharge is not associated with intravenous antibiotic completion in post-acute care facilities
Published in Therapeutic advances in infectious disease (2022)“…Background: People with opioid use disorder and severe infections may complete their prolonged courses of outpatient parenteral antimicrobial therapy at a…”
Get full text
Journal Article -
16
Genomic and neuroimaging approaches to bipolar disorder
Published in BJPsych open (01-03-2022)“…To date, besides genome-wide association studies, a variety of other genetic analyses (e.g. polygenic risk scores, whole-exome sequencing and whole-genome…”
Get full text
Journal Article -
17
-
18
High rates of tenofovir failure in a CRF01_AE-predominant HIV epidemic in the Philippines
Published in International journal of infectious diseases (01-06-2020)“…• Our study is the first systematic acquired drug resistance surveillance of HIV patients from the Philippines, which currently has one of the fastest growing…”
Get full text
Journal Article -
19
Subcortical surface morphometry in substance dependence: An ENIGMA addiction working group study
Published in Addiction biology (01-11-2020)“…While imaging studies have demonstrated volumetric differences in subcortical structures associated with dependence on various abused substances, findings to…”
Get full text
Journal Article -
20
Rifabutin Use in Staphylococcus Biofilm Infections: A Case Series
Published in Antibiotics (Basel) (01-06-2020)“…This is a case series of 10 patients who had staphylococcal biofilm infections that were treated with adjuvant rifabutin therapy instead of rifampin therapy…”
Get full text
Journal Article