Search Results - "Ching, Jared"
-
1
Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS
Published in Nature communications (05-11-2020)“…Adult mammalian central nervous system axons have intrinsically poor regenerative capacity, so axonal injury has permanent consequences. One approach to…”
Get full text
Journal Article -
2
Predictive factors for postoperative visual function in eyes with epiretinal membrane
Published in Scientific reports (14-12-2023)“…Our current study aimed to investigate the association of preoperative OCT parameters with visual function after vitrectomy surgery in eyes with epiretinal…”
Get full text
Journal Article -
3
Paclitaxel may be a risk factor for retinal phototoxicity
Published in American journal of ophthalmology case reports (01-03-2022)“…To report the first case, to our knowledge, of suspected paclitaxel induced phototoxic maculopathy following vitrectomy surgery. A 62-year-old phakic female…”
Get full text
Journal Article -
4
Physiological Electrical Signals Promote Chain Migration of Neuroblasts by Up-Regulating P2Y1 Purinergic Receptors and Enhancing Cell Adhesion
Published in Stem cell reviews (01-02-2015)“…Neuroblasts migrate as directed chains of cells during development and following brain damage. A fuller understanding of the mechanisms driving this will help…”
Get full text
Journal Article -
5
Long-term follow-up of a case of amyloidosis-associated chorioretinopathy
Published in American journal of ophthalmology case reports (01-09-2020)“…To describe the findings of long-term follow-up of a case of amyloidosis-associated chorioretinopathy by multimodal imagings, including optical coherence…”
Get full text
Journal Article -
6
A case of recurrent viral retinitis treated with intravitreal antiviral agents in a silicone oil filled eye
Published in European journal of ophthalmology (01-09-2023)“…Purpose To report a case of recurrent acute retinal necrosis (ARN) in an eye filled with silicone oil previously complicated by rhegmatogenous retinal…”
Get full text
Journal Article -
7
3D printed enucleated eye holder for research and surgical training
Published in Acta ophthalmologica (Oxford, England) (01-12-2022)“…Purpose: The aim of this study is to provide an affordable eye holder to secure enucleated eyes for the purposes of ophthalmology surgical training or…”
Get full text
Journal Article -
8
The role of vascular ultrasound in managing giant cell arteritis in ophthalmology
Published in Survey of ophthalmology (01-03-2020)“…Giant cell arteritis is the most common systemic vasculitis in the elderly and is a potentially life-threatening ophthalmic emergency that can result in…”
Get full text
Journal Article -
9
Clinically undetected retinal breaks causing retinal detachment: A review of options for management
Published in Survey of ophthalmology (01-07-2018)“…The successful detection of retinal breaks is a critical step in rhegmatogenous retinal detachment surgery in order to prevent persistent/recurrent retinal…”
Get full text
Journal Article -
10
Do ophthalmology residents know how to check the calibration of a Goldmann applanation tonometer?
Published in International ophthalmology (01-10-2023)“…Purpose The purpose of this observational study was to determine whether ophthalmology residents know how to check Goldmann applanation tonometer (GAT)…”
Get full text
Journal Article -
11
Identifying Novel Therapeutic Targets for Seizures and Brain Cancers
Published 01-01-2022“…Epilepsy describes a range of conditions characterised by unprovoked recurring seizures that are due to multiple factors including the excitatory…”
Get full text
Dissertation -
12
Leber hereditary optic neuropathy—new insights and old challenges
Published in Graefe's archive for clinical and experimental ophthalmology (01-09-2021)“…Leber hereditary optic neuropathy (LHON) is the most common primary mitochondrial DNA (mtDNA) disorder with the majority of patients harboring one of three…”
Get full text
Journal Article -
13
Quantifying inter-organelle membrane contact sites using proximity ligation assay in fixed optic nerve sections
Published in Experimental eye research (01-12-2021)“…Membrane contact sites (MCS) play crucial roles in cell physiology with dysfunction in several MCS proteins being linked with neurological and optic nerve…”
Get full text
Journal Article -
14
Glioblastoma cell migration is directed by electrical signals
Published in Experimental cell research (01-09-2021)“…Electric field (EF) directed cell migration (electrotaxis) is known to occur in glioblastoma multiforme (GBM) and neural stem cells, with key signalling…”
Get full text
Journal Article -
15
Topical prostaglandin analogue use and cystoid macular oedema following uneventful cataract surgery: a randomised control trial
Published in British journal of ophthalmology (01-12-2022)“…The association between the development of cystoid macular oedema (CMO) following uneventful cataract surgery and prostaglandin analogue (PGA) therapy has not…”
Get more information
Journal Article -
16
Is Tumour Thickness Measurement Required for MOLES Scoring of Melanocytic Choroidal Tumours?
Published in Ocular oncology and pathology (01-08-2023)“…Introduction: It can be challenging to distinguish between choroidal naevi and melanomas in the community setting, particularly without access to…”
Get full text
Journal Article -
17
Multimodal MRI can identify perfusion and metabolic changes in the invasive margin of glioblastomas
Published in Journal of magnetic resonance imaging (01-02-2016)“…Purpose To use perfusion and magnetic resonance (MR) spectroscopy to compare the diffusion tensor imaging (DTI)‐defined invasive and noninvasive regions…”
Get full text
Journal Article -
18
Variants of the EAAT2 Glutamate Transporter Gene Promoter Are Associated with Cerebral Palsy in Preterm Infants
Published in Molecular neurobiology (01-03-2018)“…Preterm delivery is associated with neurodevelopmental impairment caused by environmental and genetic factors. Dysfunction of the excitatory amino acid…”
Get full text
Journal Article -
19
Long-term effectiveness and tolerability of vagal nerve stimulation in adults with intractable epilepsy: a retrospective analysis of 100 patients
Published in British journal of neurosurgery (01-04-2013)“…Abstract Data for 100 vagal nerve stimulation (VNS) patients were collected and analysed retrospectively. The mean seizure reduction was 17.86% (n = 67) at 6…”
Get full text
Journal Article -
20
The peroxisome proliferator activated receptor gamma agonist pioglitazone increases functional expression of the glutamate transporter excitatory amino acid transporter 2 (EAAT2) in human glioblastoma cells
Published in Oncotarget (28-08-2015)“…Glioma cells release glutamate through expression of system xc-, which exchanges intracellular glutamate for extracellular cysteine. Lack of the excitatory…”
Get full text
Journal Article