Search Results - "Ching, J."

Antidiabetic Therapies Affect Risk of Pancreatic Cancer by Li, Donghui, Yeung, Sai–Ching J, Hassan, Manal M, Konopleva, Marina, Abbruzzese, James L

“…Background & Aims Antidiabetic drugs have been found to have various effects on cancer in experimental systems and in epidemiologic studies, although the…”
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Oral microbiome and onset of oral mucositis in patients with squamous cell carcinoma of the head and neck by Reyes‐Gibby, Cielito C., Wang, Jian, Zhang, Liangliang, Peterson, Christine B., Do, Kim‐Anh, Jenq, Robert R., Shelburne, Samuel, Shah, Dimpy P., Chambers, Mark S., Hanna, Ehab Y., Yeung, Sai‐Ching J., Shete, Sanjay

“…Background Oral mucositis (OM) is a debilitating sequela for patients treated for squamous cell carcinoma of the head and neck (HNSCC). This study investigated…”
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Metformin Use Is Associated with Better Survival of Diabetic Patients with Pancreatic Cancer by SADEGHI, Navid, ABBRUZZESE, James L, YEUNG, Sai-Ching J, HASSAN, Manal, DONGHUI LI

“…Accumulating evidence suggests that metformin has antitumor activity. The aim of this study was to determine whether metformin use has a survival benefit in…”
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Obesity-associated NLRC4 inflammasome activation drives breast cancer progression by Kolb, Ryan, Phan, Liem, Borcherding, Nicholas, Liu, Yinghong, Yuan, Fang, Janowski, Ann M., Xie, Qing, Markan, Kathleen R., Li, Wei, Potthoff, Matthew J., Fuentes-Mattei, Enrique, Ellies, Lesley G., Knudson, C. Michael, Lee, Mong-Hong, Yeung, Sai-Ching J., Cassel, Suzanne L., Sutterwala, Fayyaz S., Zhang, Weizhou

“…Obesity is associated with an increased risk of developing breast cancer and is also associated with worse clinical prognosis. The mechanistic link between…”
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Cardiovascular events after cancer immunotherapy as oncologic emergencies: Analyses of 610 head and neck cancer patients treated with immune checkpoint inhibitors by Reyes‐Gibby, Cielito C., Qdaisat, Aiham, Ferrarotto, Renata, Fadol, Anecita, Bischof, Jason J., Coyne, Christopher J., Lipe, Demis N., Hanna, Ehab Y., Shete, Sanjay, Abe, Jun‐Ichi, Yeung, Sai‐Ching J.

“…Background Cardio‐oncology and emergency medicine are closely collaborative, as many cardiac events in cancer patients require evaluation and treatment in the…”
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Immune Checkpoint Inhibitor Therapy in Patients With Preexisting Inflammatory Bowel Disease by Abu-Sbeih, Hamzah, Faleck, David M, Ricciuti, Biagio, Mendelsohn, Robin B, Naqash, Abdul R, Cohen, Justine V, Sellers, Maclean C, Balaji, Aanika, Ben-Betzalel, Guy, Hajir, Ibraheim, Zhang, Jiajia, Awad, Mark M, Leonardi, Giulia C, Johnson, Douglas B, Pinato, David J, Owen, Dwight H, Weiss, Sarah A, Lamberti, Giuseppe, Lythgoe, Mark P, Manuzzi, Lisa, Arnold, Christina, Qiao, Wei, Naidoo, Jarushka, Markel, Gal, Powell, Nick, Yeung, Sai-Ching J, Sharon, Elad, Dougan, Michael, Wang, Yinghong

“…The risk of immune checkpoint inhibitor therapy-related GI adverse events in patients with cancer and inflammatory bowel disease (IBD) has not been well…”
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Neoantigen‐based cancer vaccination using chimeric RNA‐loaded dendritic cell‐derived extracellular vesicles by Xiong, Xiao, Ke, Xiurong, Wang, Lu, Lin, Yusheng, Wang, Shuhong, Yao, Zhimeng, Li, Kai, Luo, Yichen, Liu, Fan, Pan, Yunlong, Yeung, Sai‐Ching J., Helfrich, Wijnand, Zhang, Hao

“…Cancer vaccines critically rely on the availability of targetable immunogenic cancer‐specific neoepitopes. However, mutation‐based immunogenic neoantigens are…”
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Oncologic emergencies and urgencies: A comprehensive review by Gould Rothberg, Bonnie E., Quest, Tammie E., Yeung, Sai‐Ching J., Pelosof, Lorraine C., Gerber, David E., Seltzer, Justin A., Bischof, Jason J., Thomas, Charles R., Akhter, Nausheen, Mamtani, Mira, Stutman, Robin E., Baugh, Christopher W., Anantharaman, Venkataraman, Pettit, Nicholas R., Klotz, Adam D., Gibbs, Michael A., Kyriacou, Demetrios N.

“…Patients with advanced cancer generate 4 million visits annually to emergency departments (EDs) and other dedicated, high‐acuity oncology urgent care centers…”
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Adverse Effects of Immune Checkpoint Therapy in Cancer Patients Visiting the Emergency Department of a Comprehensive Cancer Center by El Majzoub, Imad, Qdaisat, Aiham, Thein, Kyaw Z., Win, Myint A., Han, Myat M., Jacobson, Kalen, Chaftari, Patrick S., Prejean, Michael, Reyes-Gibby, Cielito, Yeung, Sai-Ching J.

“…Cancer immunotherapy is evolving rapidly and is transforming cancer care. During the last decade, immune checkpoint therapies have been developed to enhance…”
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ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development by Fang, Lekun, Lu, Weisi, Choi, Hyun Ho, Yeung, Sai-Ching J., Tung, Jung-Yu, Hsiao, Chwan-Deng, Fuentes-Mattei, Enrique, Menter, David, Chen, Chuangqi, Wang, Lei, Wang, Jianping, Lee, Mong-Hong

“…Biomarkers for predicting prognosis are critical to treating colorectal cancer (CRC) patients. We found that CSN6, a subunit of COP9 signalosome, is…”
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Hypomagnesemia and survival in patients with head and neck cancers who received primary concurrent chemoradiation by Liu, Wenli, Qdaisat, Aiham, Ferrarotto, Renata, Fuller, Clifton D., Guo, Ming, Meyer, Larissa A., Narayanan, Santhosshi, Lopez, Gabriel, Cohen, Lorenzo, Bruera, Eduardo, Hanna, Ehab Y., Yeung, Sai‐Ching J.

“…Background Prior research has confirmed that persistent hypomagnesemia was predictive of shorter survival among patients with ovarian cancer who received…”
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Evaluation of Salivary Exosomal Chimeric GOLM1-NAA35 RNA as a Potential Biomarker in Esophageal Carcinoma by Lin, Yusheng, Dong, Hongmei, Deng, Weilun, Lin, Wan, Li, Kai, Xiong, Xiao, Guo, Yi, Zhou, Fuyou, Ma, Changchun, Chen, Yuping, Ren, Hongzheng, Yang, Haijun, Dai, Ningtao, Ma, Lang, Meltzer, Stephen J, Yeung, Sai-Ching J, Zhang, Hao

“…Transcriptionally induced chimeric RNAs are an important emerging area of research into molecular signatures for biomarker and therapeutic target development…”
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Survival after pulmonary metastasectomy for relapsed osteosarcoma by Liu, Zhenguo, Yin, Junqiang, Zhou, Qian, Yang, Jiali, Zeng, Bo, Yeung, Sai-Ching J., Shen, Jingnan, Cheng, Chao

“…The purpose of this study was to evaluate the postrelapse survival of relapsed osteosarcoma with pulmonary metastases in patients who received pulmonary…”
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An updated Asia Pacific Consensus Recommendations on colorectal cancer screening by Sung, J J Y, Ng, S C, Chan, F K L, Chiu, H M, Kim, H S, Matsuda, T, Ng, S S M, Lau, J Y W, Zheng, S, Adler, S, Reddy, N, Yeoh, K G, Tsoi, K K F, Ching, J Y L, Kuipers, E J, Rabeneck, L, Young, G P, Steele, R J, Lieberman, D, Goh, K L

“…Since the publication of the first Asia Pacific Consensus on Colorectal Cancer (CRC) in 2008, there are substantial advancements in the science and experience…”
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Early clinical experience of the safety and effectiveness of Hemospray in achieving hemostasis in patients with acute peptic ulcer bleeding by Sung, J J Y, Luo, D, Wu, J C Y, Ching, J Y L, Chan, F K L, Lau, J Y W, Mack, S, Ducharme, R, Okolo, P, Canto, M, Kalloo, A, Giday, S A

“…Endoscopic therapy of upper gastrointestinal bleeding remains challenging with conventional endoscopic devices. Use of Hemospray, where a nanopowder with…”
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Human Immunodeficiency Virus/AIDS, Human Papillomavirus, and Anal Cancer by Wang, Chia-ching J., MD, Sparano, Joseph, MD, Palefsky, Joel M., MD

“…Anal cancer is an increasingly common non–AIDS-defining cancer among individuals infected with the human immunodeficiency virus (HIV). It is associated with…”
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A new paradigm for classifying and treating HER2‐positive breast cancer by He, Xuexin, Yeung, Sai‐Ching J., Esteva, Francisco J.

“…Background Because of the phenomenal success of treatment with monoclonal antibodies and antibody‐drug conjugates targeting human epidermal growth factor…”
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Targeting Vascular Endothelial Growth Factor in Advanced Carcinoid Tumor: A Random Assignment Phase II Study of Depot Octreotide With Bevacizumab and Pegylated Interferon Alfa-2b by YAO, James C, PHAN, Alexandria, HOFF, Paulo M, CHEN, Helen X, CHARNSANGAVEJ, Chusilp, YEUNG, Sai-Ching J, HESS, Kenneth, NG, Chaan, ABBRUZZESE, James L, AJANI, Jaffer A

“…Purpose Effective systemic therapy for advanced carcinoid is lacking. The combination of bevacizumab (BEV) and pegylated (PEG) interferon alfa-2b was evaluated…”
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Diabetic ketoacidosis induced by a single dose of pembrolizumab by Maamari, Julian, Yeung, Sai-Ching J., Chaftari, Patrick S.

“…Immune checkpoint inhibitors are a new class of anticancer drugs recently approved by the US Food and Drug Administration (FDA) for the treatment of various…”
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Roles of COP9 signalosome in cancer by Lee, Mong-Hong, Zhao, Ruiying, Phan, Liem, Yeung, Sai-Ching J.

“…The constitutive photomorphogenesis 9 signalosome (COP9 or CSN) is an evolutionarily conserved multiprotein complex found in plants and animals. Because of the…”
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