Search Results - "Chin, Yiap Beow"

Site-Directed Mutagenesis of Cytochrome P450 2D6 and 2C19 Enzymes: Expression and Spectral Characterization of Naturally Occurring Allelic Variants by Dong, Amelia Nathania, Pan, Yan, Palanisamy, Uma Devi, Yiap, Beow Chin, Ahemad, Nafees, Ong, Chin Eng

“…Genetic polymorphism of the cytochrome P450 (CYP) genes particularly affects CYP2D6 and CYP2C19 to a functionally relevant extent, and it is therefore crucial…”
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Cloning of a novel phytase from an anaerobic rumen bacterium, Mitsuokella jalaludinii, and its expression in Escherichia coli by TAN, Wan-qin, Yee, Phang Chiun, Chin, Sieo Chin, Chin, Yiap Beow, Clemente Michael Wong Vui, Ling, Abdullah, Norhani, Radu, Son, Wan, Ho Yin

“…The full length phytase gene of Mitsuokellajalaludiniiwas successfully cloned and was found to be 1 047 bp in length, with 348 amino acids, and was designated…”
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DNA, RNA, and Protein Extraction : The Past and The Present by Tan, Siun Chee, Yiap, Beow Chin

“…Extraction of DNA, RNA, and protein is the basic method used in molecular biology. These biomolecules can be isolated from any biological material for…”
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Combination of essential oils and antibiotics reduce antibiotic resistance in plasmid-conferred multidrug resistant bacteria by Yap, Polly Soo Xi, Lim, Swee Hua Erin, Hu, Cai Ping, Yiap, Beow Chin

“…In this study we investigated the relationship between several selected commercially available essential oils and beta-lactam antibiotics on their…”
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Functional and structural characterisation of common cytochrome P450 2D6 allelic variants—roles of Pro34 and Thr107 in catalysis and inhibition by Dong, Amelia Nathania, Ahemad, Nafees, Pan, Yan, Palanisamy, Uma Devi, Yiap, Beow Chin, Ong, Chin Eng

“…One major source of inter-individual variability in drug pharmacokinetics is genetic polymorphism of the cytochrome P450 ( CYP ) genes. This study aimed to…”
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Cytochrome P450 2C9‐natural antiarthritic interactions: Evaluation of inhibition magnitude and prediction from in vitro data by Tan, Boon Hooi, Ahemad, Nafees, Pan, Yan, Palanisamy, Uma Devi, Othman, Iekhsan, Yiap, Beow Chin, Ong, Chin Eng

“…Many dietary supplements are promoted to patients with osteoarthritis (OA) including the three naturally derived compounds, glucosamine, chondroitin and…”
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Inhibitory Potency of 8-Methoxypsoralen on Cytochrome P450 2A6 (CYP2A6) Allelic Variants CYP2A615, CYP2A616, CYP2A621 and CYP2A622: Differential Susceptibility Due to Different Sequence Locations of the Mutations by Tiong, Kai Hung, Mohammed Yunus, Nafees Ahemad, Yiap, Beow Chin, Tan, Eng Lai, Ismail, Rusli, Ong, Chin Eng

“…Human cytochrome P450 2A6 (CYP2A6) is a highly polymorphic isoform of CYP2A subfamily. Our previous kinetic study on four CYP2A6 allelic variants (CYP2A6*15,…”
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Functional Characterization of Cytochrome P450 2A6 Allelic Variants CYP2A615, CYP2A616, CYP2A621, and CYP2A622 by KAI HUNG TIONG, BEOW CHIN YIAP, ENG LAI TAN, ISMAIL, Rusli, CHIN ENG ONG

“…Variation in CYP2A6 levels and activity can be attributed to genetic polymorphism and, thus, functional characterization of allelic variants is necessary to…”
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Inhibitory potency of 8-methoxypsoralen on cytochrome P450 2A6 (CYP2A6) allelic variants CYP2A6 15, CYP2A6 16, CYP2A6 21 and CYP2A6 22: differential susceptibility due to different sequence locations of the mutations by Tiong, Kai Hung, Mohammed Yunus, Nafees Ahemad, Yiap, Beow Chin, Tan, Eng Lai, Ismail, Rusli, Ong, Chin Eng

“…Human cytochrome P450 2A6 (CYP2A6) is a highly polymorphic isoform of CYP2A subfamily. Our previous kinetic study on four CYP2A6 allelic variants (CYP2A6 15,…”
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DSN1 deletion is deleterious to the Saccharomyces cerevisiae while Dsn1p disrupts nuclear segregation process of Chinese Hamster Ovary cell by Yiap, B C, Radhakrishnan, A K, Varma, NRS

“…Dsn1p is a component of the mind complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) that is essential for the segregation of chromosome in yeast cells. This protein…”
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Essential oils, a new horizon in combating bacterial antibiotic resistance by Yap, Polly Soo Xi, Yiap, Beow Chin, Ping, Hu Cai, Lim, Swee Hua Erin

“…For many years, the battle between humans and the multitudes of infection and disease causing pathogens continues. Emerging at the battlefield as some of the…”
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Role of P34S, G169R, R296C, and S486T Substitutions in Ligand Access and Catalysis for Cytochrome P450 2D6 Allelic Variants CYP2D614A and CYP2D614B by Dong, Amelia Nathania, Ahemad, Nafees, Pan, Yan, Palanisamy, Uma Devi, Yiap, Beow Chin, Ong, Chin Eng

“…Genetic polymorphism of cytochrome P450 (CYP) contributes to variability in drug metabolism, clearance, and response. This study aimed to investigate the…”
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Erratum to “DNA, RNA, and Protein Extraction: The Past and the Present” by Tan, Siun Chee, Yiap, Beow Chin

“…The date “1893” in the end of the sentence “However, the first description of protein was carried out by Gerhardus Johannes Mulder, a Dutch chemist, in 1893”…”
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Inhibitory Potency of 8-Methoxypsoralen on Cytochrome P450 2A6 by Tiong, Kai Hung, Mohammed Yunus, Nafees Ahemad, Yiap, Beow Chin, Tan, Eng Lai, Ismail, Rusli, Ong, Chin Eng

“…Human cytochrome P450 2A6 (CYP2A6) is a highly polymorphic isoform of CYP2A subfamily. Our previous kinetic study on four CYP2A6 allelic variants (CYP2A6*15,…”
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Expression of cytochrome P450 2C9 (CYP2C9) in Escherichia coli and its functional characterization by Tan, Boon Hooi, Pan, Yan, Palanisamy, Uma Devi, Othman, Iekhsan, Ahmed, Nafees, Yiap, Beow Chin, Ong, Chin Eng

“…This study aimed to express the major human hepatic drug metabolizing cytochrome P450 (CYP), CYP2C9, together with NADPH cytochrome P450 oxidoreductase (OxR)…”
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Inhibitory Potency of 8-Methoxypsoralen on Cytochrome P450 2A6 (CYP2A6) Allelic Variants CYP2A615, CYP2A616, CYP2A621 and CYP2A622: Differential Susceptibility Due to Different Sequence Locations of the Mutations: e86230 by Tiong, Kai Hung, Yunus, Nafees AhemadMohammed, Yiap, Beow Chin, Tan, Eng Lai, Ismail, Rusli, Ong, Chin Eng

“…Human cytochrome P450 2A6 (CYP2A6) is a highly polymorphic isoform of CYP2A subfamily. Our previous kinetic study on four CYP2A6 allelic variants (CYP2A6*15,…”
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Saccharomyces cerevisiae Kinetochore Protein (rDsn1p) Induced Apoptosis in Chinese Hamster Ovary Cells by Yiap, B-C, Raha, A-R, Radhakrishnan, A K

“…Dsn1p is a member of the MIND complex that forms part of the yeast kinetochore, which is essential for the proper chromosomal segregation during cell division…”
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