Search Results - "Chin, J D"

Characterization of Hepatitis C Virus (HCV) Quasispecies Dynamics upon Short-Term Dual Therapy with the HCV NS5B Nucleoside Polymerase Inhibitor Mericitabine and the NS3/4 Protease Inhibitor Danoprevir by LE POGAM, S, YAN, J. M, KLUMPP, K, NAJERA, I, CHHABRA, M, ILNICKA, M, KANG, H, KOSAKA, A, ALI, S, CHIN, D. J, SHULMAN, N. S, SMITH, P

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Phosphatidylinositol 3′‐kinase is activated by association with IRS‐1 during insulin stimulation by Backer, J.M., Myers, M.G., Shoelson, S.E., Chin, D.J., Sun, X.J., Miralpeix, M., Hu, P., Margolis, B., Skolnik, E.Y., Schlessinger, J.

“…IRS‐1 undergoes rapid tyrosine phosphorylation during insulin stimulation and forms a stable complex containing the 85 kDa subunit (p85) of the…”
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Association of IRS-1 with the insulin receptor and the phosphatidylinositol 3'-kinase. Formation of binary and ternary signaling complexes in intact cells by J M Backer, M G Myers, Jr, X J Sun, D J Chin, S E Shoelson, M Miralpeix, M F White

“…Insulin stimulates the formation of binary and ternary signaling complexes between the phosphatidylinositol (PtdIns) 3'-kinase, IRS-1, and the insulin receptor…”
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Intracellular oligonucleotide hybridization detected by fluorescence resonance energy transfer (FRET) by Sixou, S., Szoka, F.C., Green, G.A., Giusti, B., Zon, G., Chin, D.J.

“…Fluorescence resonance energy transfer (FRET) was used to study hybrid formation and dissociation after microinjection of ollgonucleotldes (ODNs) Into living…”
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Characterization of the nuclear export signal of human T-cell lymphotropic virus type 1 Rex reveals that nuclear export is mediated by position-variable hydrophobic interactions by Kim, Felix J., Beeche, Arlyne A., Hunter, John J., Chin, Daniel J., Hope, Thomas J.

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100-kDa Polypeptides in Peripheral Clathrin-Coated Vesicles are Required for Receptor-Mediated Endocytosis by Chin, Daniel J., Straubinger, Robert M., Acton, Susan, Näthke, Inke, Brodsky, Frances M.

“…The role of the 100-kDa polypeptide components of clathrin-coated vesicles in endocytosis was investigated by microinjection of specific monoclonal antibodies…”
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Inhibition of human immunodeficiency virus type 1 Rev-Rev-response element complex formation by complementary oligonucleotides by CHIN, D. J

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Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme by Gil, G, Faust, J R, Chin, D J, Goldstein, J L, Brown, M S

“…3-Hydroxy-3-methylglutaryl coenzyme A reductase (HMG CoA reductase) is a single polypeptide chain with two contiguous domains: a soluble domain (548 amino…”
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Developmental and metabolic regulation of the Drosophila melanogaster 3-hydroxy-3-methylglutaryl coenzyme A reductase by Gertler, F B, Chiu, C Y, Richter-Mann, L, Chin, D J

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Amplification of the gene for 3-hydroxy-3-methylglutaryl coenzyme A reductase, but not for the 53-kDa protein, in UT-1 cells by Luskey, K L, Faust, J R, Chin, D J, Brown, M S, Goldstein, J L

“…32P-labeled cDNA probes were used to study levels of genomic DNA and regulation of mRNA for 3-hydroxy-3-methylglutaryl coenzyme A reductase in UT-1 cells, a…”
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A role for receptor tyrosine phosphataseζ in glioma cell migration by MÜLLER, Sabine, KUNKEL, Philip, MELCHER, Thorsten, LAMSZUS, Katrin, ULBRICHT, Ulrike, LORENTE, Gustavo Angel, NELSON, April Michelle, VON SCHACK, David, CHIN, Daniel J, LOHR, Scott Curtis, WESTPHAL, Manfred

“…Glioblastomas (GBM) are the most frequent and malignant human brain tumor type. Typically striking in adulthood, tumor progression is rapid, relentless, and…”
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Regulation of Synthesis and Degradation of 3-hydroxy-3-methylglutaryl-coenzyme A Reductase by Low Density Lipoprotein and 25-hydroxycholesterol in UT-1 Cells by Faust, Jerry R., Luskey, Kenneth L., Chin, Daniel J., Goldstein, Joseph L., Brown, Michael S.

“…UT-1 cells are a clone of Chinese hamster ovary cells that were selected to grow in the presence of compactin, a competitive inhibitor of…”
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Sterols accelerate degradation of hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase encoded by a constitutively expressed cDNA by Chin, D J, Gil, G, Faust, J R, Goldstein, J L, Brown, M S, Luskey, K L

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Appearance of Crystalloid Endoplasmic Reticulum in Compactin-Resistant Chinese Hamster Cells with a 500-Fold Increase in 3-hydroxy-3-methylglutaryl-coenzyme A Reductase by Chin, Daniel J., Luskey, Kenneth L., Richard G. W. Anderson, Faust, Jerry R., Goldstein, Joseph L., Brown, Michael S.

“…We have developed a line of Chinese hamster ovary cells with a 500-fold increase in 3-hydroxy-3-methylglutarylcoenzyme A reductase, the membrane-bound enzyme…”
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Screening for okadaic acid by immunoassay by Chin, J D, Quilliam, M A, Fremy, J M, Mohapatra, S K, Sikorska, H M

“…Increasing incidences of phytoplankton blooms with the potential danger of toxin release into the food chain have necessitated the search for new diagnostic…”
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Human immunodeficiency virus type 1 Tat does not transactivate mature trans-acting responsive region RNA species in the nucleus or cytoplasm of primate cells by CHIN, D. J, SELBY, M. J, PETERLIN, B. M

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Nucleotide sequence of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, a glycoprotein of endoplasmic reticulum by Chin, Daniel J, Gil, Gregorio, Russell, David W, Liscum, Laura, Luskey, Kenneth L, Basu, Sandip K, Okayama, Hiroto, Berg, Paul, Goldstein, Joseph L, Brown, Michael S

“…The nucleotide sequence of a 4.8-kilobase mRNA for hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase, the endoplasmic reticulum enzyme that controls…”
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Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its mRNA in rat liver as studied with a monoclonal antibody and a cDNA probe by Liscum, L, Luskey, K L, Chin, D J, Ho, Y K, Goldstein, J L, Brown, M S

“…A monoclonal antibody directed against 3-hydroxy-3-methylglutaryl Coenzyme A reductase and a cDNA to reductase mRNA were used to study the subunit structure of…”
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Molecular Cloning of 3-hydroxy-3-methylglutaryl Coenzyme A Reductase and Evidence for Regulation of Its mRNA by Chin, Daniel J., Luskey, Kenneth L., Faust, Jerry R., MacDonald, Raymond J., Brown, Michael S., Goldstein, Joseph L.

“…A recombinant plasmid containing a 1.2-kilobase cDNA for 3-hydroxy-3-methylglutaryl coenzyme A reductase was isolated from a cDNA library prepared from UT-1…”
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Identification of a Cholesterol-Regulated 53,000-Dalton Cytosolic Protein in UT-1 Cells and Cloning of Its cDNA by Luskey, Kenneth L., Chin, Daniel J., MacDonald, Raymond J., Liscum, Laura, Goldstein, Joseph L., Brown, Michael S.

“…UT-1 cells, a clone of Chinese hamster ovary (CHO) cells, have a 100- to 1,000-fold elevation in the amount of 3-hydroxy-3-methylglutaryl CoA reductase and…”
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