Search Results - "Chin, Deborah"

miR-145 micelles mitigate atherosclerosis by modulating vascular smooth muscle cell phenotype by Chin, Deborah D., Poon, Christopher, Wang, Jonathan, Joo, Johan, Ong, Victor, Jiang, Zhangjingyi, Cheng, Kayley, Plotkin, Anastasia, Magee, Gregory A., Chung, Eun Ji

“…In atherosclerosis, resident vascular smooth muscle cells (VSMCs) in the blood vessels become highly plastic and undergo phenotypic switching from the…”
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Changing Prevalence of Potential Mediators of Aminoquinoline, Antifolate, and Artemisinin Resistance Across Uganda by Asua, Victor, Conrad, Melissa D, Aydemir, Ozkan, Duvalsaint, Marvin, Legac, Jennifer, Duarte, Elias, Tumwebaze, Patrick, Chin, Deborah M, Cooper, Roland A, Yeka, Adoke, Kamya, Moses R, Dorsey, Grant, Nsobya, Sam L, Bailey, Jeffrey, Rosenthal, Philip J

“…Abstract Background In Uganda, artemether-lumefantrine is recommended for malaria treatment and sulfadoxine-pyrimethamine for chemoprevention during pregnancy,…”
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Exosomes in Atherosclerosis, a Double-Edged Sword: Their Role in Disease Pathogenesis and Their Potential as Novel Therapeutics by Patel, Neil, Chin, Deborah D., Chung, Eun Ji

“…Cardiovascular disease (CAD) due to atherosclerosis is a major cause of death worldwide. The development of atherosclerosis involves intercellular…”
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Long-term, in vivo therapeutic effects of a single dose of miR-145 micelles for atherosclerosis by Chin, Deborah D., Patel, Neil, Lee, Woori, Kanaya, Sonali, Cook, Jackson, Chung, Eun Ji

“…Atherosclerosis is a chronic inflammatory disease that is characterized by the build-up of lipid-rich plaques in the arterial walls. The standard treatment for…”
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Therapeutic Response of miR-145 Micelles on Patient-Derived Vascular Smooth Muscle Cells by Patel, Neil, Chin, Deborah D., Magee, Gregory A., Chung, Eun Ji

“…During atherosclerosis, vascular smooth muscle cells (VSMCs) undergo a phenotypic transition from a healthy contractile state into pathological phenotypes…”
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Hydroxyapatite-binding micelles for the detection of vascular calcification in atherosclerosis by Chin, Deborah D, Wang, Jonathan, Mel de Fontenay, Margot, Plotkin, Anastasia, Magee, Gregory A, Chung, Eun Ji

“…Atherosclerosis is a chronic disease characterized by the formation of calcified, arterial plaques. Microcalcifications (5 μm to 100 μm), mainly composed of…”
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Collagenase‐Cleavable Peptide Amphiphile Micelles as a Novel Theranostic Strategy in Atherosclerosis by Chin, Deborah D., Poon, Christopher, Trac, Noah, Wang, Jonathan, Cook, Jackson, Joo, Johan, Jiang, Zhangjingyi, Sta Maria, Naomi Sulit, Jacobs, Russell E., Chung, Eun Ji

“…Atherosclerosis is an inflammatory disease characterized by plaques that can cause sudden myocardial infarction upon rupture. Such rupture‐prone plaques have…”
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Calcium-Binding Nanoparticles for Vascular Disease by Chin, Deborah D., Chowdhuri, Sampreeti, Chung, Eun Ji

“…Cardiovascular disease (CVD) including atherosclerosis is the leading cause of death worldwide. As CVDs and atherosclerosis develop, plaques begin to form in…”
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Oral delivery of metformin by chitosan nanoparticles for polycystic kidney disease by Wang, Jonathan, Chin, Deborah, Poon, Christopher, Mancino, Valeria, Pham, Jessica, Li, Hui, Ho, Pei-Yin, Hallows, Kenneth R., Chung, Eun Ji

“…Nanoparticle drug delivery has many advantages over small molecule therapeutics, including reducing off-target side effects and increasing drug potency…”
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Design and in vivo characterization of kidney-targeting multimodal micelles for renal drug delivery by Wang, Jonathan, Poon, Christopher, Chin, Deborah, Milkowski, Sarah, Lu, Vivian, Hallows, Kenneth R., Chung, Eun Ji

“…One in three Americans is at risk for developing chronic kidney disease (CKD) and end-stage renal disease (ESRD), leading to the need for dialysis or a kidney…”
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Expression Microdissection for the Analysis of miRNA in a Single-Cell Type by Jenike, Ana E., Bunkelman, Brady, Perzel Mandell, Kira A., Oduor, Cliff I., Chin, Deborah, Mair, Devin, Jenike, Katharine M., Kim, Deok-Ho, Bailey, Jeffrey A., Rafailovich, Miriam H., Rosenberg, Avi Z., Halushka, Marc K.

“…Cell-specific microRNA (miRNA) expression estimates are important in characterizing the localization of miRNA signaling within tissues. Much of these data are…”
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A microfluidic cell-migration assay for the prediction of progression-free survival and recurrence time of patients with glioblastoma by Wong, Bin Sheng, Shah, Sagar R., Yankaskas, Christopher L., Bajpai, Vivek K., Wu, Pei-Hsun, Chin, Deborah, Ifemembi, Brent, ReFaey, Karim, Schiapparelli, Paula, Zheng, Xiaobin, Martin, Stuart S., Fan, Chen-Ming, Quiñones-Hinojosa, Alfredo, Konstantopoulos, Konstantinos

“…Clinical scores, molecular markers and cellular phenotypes have been used to predict the clinical outcomes of patients with glioblastoma. However, their…”
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Oral delivery of nanomedicine for genetic kidney disease by Huang, Yi, Wang, Jonathan, Mancino, Valeria, Pham, Jessica, O'Grady, Colette, Li, Hui, Jiang, Kairui, Chin, Deborah, Poon, Christopher, Ho, Pei-Yin, Gyarmati, Georgina, Peti-Peterdi, János, Hallows, Kenneth R, Chung, Eun Ji

“…Chronic and genetic kidney diseases such as autosomal dominant polycystic kidney disease (ADPKD) have few therapeutic options, and clinical trials testing…”
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1.2.3 Getting the Message Across ‐ Creating Accessible Guides to Promote the Adoption of Systems Engineering Good Practices by Armitage, Tim, Elliott, Bruce, Chin, Deborah, Kastenhuber, Ed, Krueger, Michael E.

“…The authors believe that better deployment of Systems Engineering (SE) would benefit the rail and transit sector. They have formed an INCOSE working group to…”
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