Search Results - "Chin, Chung Man"

Special Issue “Drug Candidates for the Treatment of Infectious Diseases” by Man Chin, Chung, Dos Santos, Jean Leandro

“…Infectious diseases encompass a range of conditions stemming from parasites [...]…”
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Unraveling the Anticancer Effect of Curcumin and Resveratrol by Pavan, Aline Renata, Silva, Gabriel Dalio Bernardes da, Jornada, Daniela Hartmann, Chiba, Diego Eidy, Fernandes, Guilherme Felipe Dos Santos, Man Chin, Chung, Dos Santos, Jean Leandro

“…Resveratrol and curcumin are natural products with important therapeutic properties useful to treat several human diseases, including cancer. In the last…”
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Design and Synthesis of Hybrid Compounds as Epigenetic Modifiers by Lopes, Juliana Romano, Prokopczyk, Igor Muccilo, Gerlack, Max, Man Chin, Chung, Santos, Jean Leandro Dos

“…Epigenetic modifiers acting through polypharmacology mechanisms are promising compounds with which to treat several infectious diseases. Histone deacetylase…”
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A prodrug approach to improve the physico-chemical properties and decrease the genotoxicity of nitro compounds by Chung, Man Chin, Bosquesi, Priscila Longhin, dos Santos, Jean Leandro

“…In therapeutics research, the nitro compounds are part of an important group of drugs with multiple pharmacological activities. However, in drug design, the…”
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Advances in Drug Discovery of New Antitubercular Multidrug-Resistant Compounds by Fernandes, Guilherme Felipe Dos Santos, Man Chin, Chung, Dos Santos, Jean Leandro

“…Tuberculosis (TB), a disease caused mainly by the , is according to the World Health Organization (WHO) the infectious disease responsible for the highest…”
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High-speed fiber laser cutting of thick stainless steel for dismantling tasks by Shin, Jae Sung, Oh, Seong Yong, Park, Hyunmin, Chung, Chin-Man, Seon, Sangwoo, Kim, Taek-Soo, Lee, Lim, Choi, Byung-Seon, Moon, Jei-Kwon

“…•A new cutting head and our own laser cutting techniques were developed for dismantling tasks.•The cutting performance was studied using the developed cutting…”
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Perspectives and challenges to discovering hemoglobin-inducing agents in Sickle Cell Disease by Pavan, Aline Renata, Lopes, Juliana Romano, Lima Imperador, Carlos Henrique, Man Chin, Chung, dos Santos, Jean Leandro

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Current Advances in Antitubercular Drug Discovery: Potent Prototypes and New Targets by Dos Santos Fernandes, Guilherme Felipe, Jornada, Daniela Hartmann, de Souza, Paula Carolina, Chin, Chung Man, Pavan, Fernando Rogerio, Dos Santos, Jean Leandro

“…Tuberculosis (TB) is an infectious disease caused by bacterium of the Mycobacterium genus, mainly by Mycobacterium tuberculosis (MTB). The World Health…”
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Dietary Compound Resveratrol Is a Pan-BET Bromodomain Inhibitor by Dutra, Luiz Antonio, Heidenreich, David, Silva, Gabriel Dalio Bernardes da, Man Chin, Chung, Knapp, Stefan, Santos, Jean Leandro Dos

“…The chemopreventive and anticancer effects of resveratrol (RSV) are widely reported in the literature. Specifically, mechanisms involving epigenetic regulation…”
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Prodrugs for the treatment of neglected diseases by Chung, Man Chin, Ferreira, Elizabeth Igne, Santos, Jean Leandro, Giarolla, Jeanine, Rando, Daniela Gonçales, Almeida, Adélia Emília, Bosquesi, Priscila Longhin, Menegon, Renato Farina, Blau, Lorena

“…Recently, World Health Organization (WHO) and Medicins San Frontieres (MSF) proposed a classification of diseases as global, neglected and extremely neglected…”
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Current advances in drug discovery for Chagas disease by Scarim, Cauê Benito, Jornada, Daniela Hartmann, Chelucci, Rafael Consolin, de Almeida, Leticia, dos Santos, Jean Leandro, Chung, Man Chin

“…Chagas disease, also known as American trypanosomiasis, is one of the 17 neglected tropical diseases (NTDs) according to World Health Organization. It is…”
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The Prodrug Approach: A Successful Tool for Improving Drug Solubility by Jornada, Daniela Hartmann, dos Santos Fernandes, Guilherme Felipe, Chiba, Diego Eidy, de Melo, Thais Regina Ferreira, dos Santos, Jean Leandro, Chung, Man Chin

“…Prodrug design is a widely known molecular modification strategy that aims to optimize the physicochemical and pharmacological properties of drugs to improve…”
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Underwater cutting of 50 and 60 mm thick stainless steel plates using a 6-kW fiber laser for dismantling nuclear facilities by Shin, Jae Sung, Oh, Seong Yong, Park, Hyunmin, Kim, Taek-Soo, Lee, Lim, Chung, Chin-Man, Lee, Jonghwan

“…•Underwater laser cutting studies on thick stainless steel plates was performed.•An underwater cutting head was developed by upgrading our previous head.•50…”
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Advances in sickle cell disease treatment: from drug discovery until the patient monitoring by dos Santos, Jean Leandro, Lanaro, Carolina, Chin, Chung Man

“…Sickle cell disease (SCD) is one of the most prevalent hematological diseases in the world. Despite the immense progress in molecular knowledge about SCD in…”
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Laser cutting of steel plates up to 100 mm in thickness with a 6-kW fiber laser for application to dismantling of nuclear facilities by Shin, Jae Sung, Oh, Seong Yong, Park, Hyunmin, Chung, Chin-Man, Seon, Sangwoo, Kim, Taek-Soo, Lee, Lim, Lee, Jonghwan

“…•A cutting study with a high power ytterbium-doped fiber laser was conducted for application to dismantling of nuclear facilities.•Stainless steel and carbon…”
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Epigenetic Regulatory Mechanisms Induced by Resveratrol by Fernandes, Guilherme Felipe Santos, Silva, Gabriel Dalio Bernardes, Pavan, Aline Renata, Chiba, Diego Eidy, Chin, Chung Man, Dos Santos, Jean Leandro

“…Resveratrol (RVT) is one of the main natural compounds studied worldwide due to its potential therapeutic use in the treatment of many diseases, including…”
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Effect of nozzle types on the laser cutting performance for 60-mm-thick stainless steel by Oh, Seong Y., Shin, Jae Sung, Kim, Taek Soo, Park, Hyunmin, Lee, Lim, Chung, Chin-Man, Lee, Jonghwan

“…•Gas flow behavior emerging from nozzles was studied by interferometric analysis.•Weak or no shockwaves were observed in supersonic nozzles.•Stainless steel…”
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Discovery of Novel Inhibitors of Cruzain Cysteine Protease of Trypanosoma cruzi by Prates, João Lucas Bruno, Lopes, Juliana Romano, Chin, Chung Man, Ferreira, Elizabeth Igne, Dos Santos, Jean Leandro, Scarim, Cauê Benito

“…Chagas disease (CD) is a parasitic disease endemic in several developing countries. According to the World Health Organization, approximately 6-8 million…”
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Nitroheterocyclic derivatives: privileged scaffold for drug development against Chagas disease by Benito Scarim, Cauê, Man Chin, Chung

“…Chagas disease or American trypanosomiasis is a major public health problem in Latin America. Approximately seven million people are currently infected…”
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Taurine Neuroprotection and Neurogenesis Effect in Chronic Ethanol-Induced Rats by Rodella, Patricia, Boreski, Diogo, Luz, Marcus Alexandre Mendes, Gabriel, Edmo Atique, Takase, Luiz Fernando, Chin, Chung Man

“…Taurine (2-aminoethanesulfonic acid) is a non-protein β-amino acid essential for cellular homeostasis, with antioxidant, anti-inflammatory, and cytoprotective…”
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