Search Results - "Chin, Alana M"

Morphogenesis and maturation of the embryonic and postnatal intestine by Chin, Alana M., Hill, David R., Aurora, Megan, Spence, Jason R.

“…The intestine is a vital organ responsible for nutrient absorption, bile and waste excretion, and a major site of host immunity. In order to keep up with daily…”
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In Vitro Induction and In Vivo Engraftment of Lung Bud Tip Progenitor Cells Derived from Human Pluripotent Stem Cells by Miller, Alyssa J., Hill, David R., Nagy, Melinda S., Aoki, Yoshiro, Dye, Briana R., Chin, Alana M., Huang, Sha, Zhu, Felix, White, Eric S., Lama, Vibha, Spence, Jason R.

“…The current study aimed to understand the developmental mechanisms regulating bud tip progenitor cells in the human fetal lung, which are present during…”
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Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium by Hill, David R, Huang, Sha, Nagy, Melinda S, Yadagiri, Veda K, Fields, Courtney, Mukherjee, Dishari, Bons, Brooke, Dedhia, Priya H, Chin, Alana M, Tsai, Yu-Hwai, Thodla, Shrikar, Schmidt, Thomas M, Walk, Seth, Young, Vincent B, Spence, Jason R

“…The human gastrointestinal tract is immature at birth, yet must adapt to dramatic changes such as oral nutrition and microbial colonization. The confluence of…”
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In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development by Tsai, Yu-Hwai, Nattiv, Roy, Dedhia, Priya H, Nagy, Melinda S, Chin, Alana M, Thomson, Matthew, Klein, Ophir D, Spence, Jason R

“…The intestine plays a central role in digestion, nutrient absorption and metabolism, with individual regions of the intestine having distinct functional roles…”
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Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo by Finkbeiner, Stacy R., Hill, David R., Altheim, Christopher H., Dedhia, Priya H., Taylor, Matthew J., Tsai, Yu-Hwai, Chin, Alana M., Mahe, Maxime M., Watson, Carey L., Freeman, Jennifer J., Nattiv, Roy, Thomson, Matthew, Klein, Ophir D., Shroyer, Noah F., Helmrath, Michael A., Teitelbaum, Daniel H., Dempsey, Peter J., Spence, Jason R.

“…Human intestinal organoids (HIOs) are a tissue culture model in which small intestine-like tissue is generated from pluripotent stem cells. By carrying out…”
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Smad6 is essential to limit BMP signaling during cartilage development by Estrada, Kristine D, Retting, Kelsey N, Chin, Alana M, Lyons, Karen M

“…Bone morphogenetic protein (BMP) signaling pathways regulate multiple aspects of endochondral bone formation. The importance of extracellular antagonists as…”
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A Dynamic WNT/β-CATENIN Signaling Environment Leads to WNT-Independent and WNT-Dependent Proliferation of Embryonic Intestinal Progenitor Cells by Chin, Alana M., Tsai, Yu-Hwai, Finkbeiner, Stacy R., Nagy, Melinda S., Walker, Emily M., Ethen, Nicole J., Williams, Bart O., Battle, Michele A., Spence, Jason R.

“…Much of our understanding about how intestinal stem and progenitor cells are regulated comes from studying the late fetal stages of development and the adult…”
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Identification, isolation and characterization of human LGR5-positive colon adenoma cells by Dame, Michael K, Attili, Durga, McClintock, Shannon D, Dedhia, Priya H, Ouillette, Peter, Hardt, Olaf, Chin, Alana M, Xue, Xiang, Laliberte, Julie, Katz, Erica L, Newsome, Gina M, Hill, David R, Miller, Alyssa J, Tsai, Yu-Hwai, Agorku, David, Altheim, Christopher H, Bosio, Andreas, Simon, Becky, Samuelson, Linda C, Stoerker, Jay A, Appelman, Henry D, Varani, James, Wicha, Max S, Brenner, Dean E, Shah, Yatrik M, Spence, Jason R, Colacino, Justin A

“…The intestine is maintained by stem cells located at the base of crypts and distinguished by the expression of LGR5. Genetically engineered mouse models have…”
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Expression-Based Cell Lineage Analysis in Drosophila Through a Course-Based Research Experience for Early Undergraduates by Olson, John M, Evans, Cory J, Ngo, Kathy T, Kim, Hee Jong, Nguyen, Joseph Duy, Gurley, Kayla G H, Ta, Truc, Patel, Vijay, Han, Lisa, Truong-N, Khoa T, Liang, Letty, Chu, Maggie K, Lam, Hiu, Ahn, Hannah G, Banerjee, Abhik Kumar, Choi, In Young, Kelley, Ross G, Moridzadeh, Naseem, Khan, Awais M, Khan, Omair, Lee, Szuyao, Johnson, Elizabeth B, Tigranyan, Annie, Wang, Jay, Gandhi, Anand D, Padhiar, Manish M, Calvopina, Joseph Hargan, Sumra, Kirandeep, Ou, Kristy, Wu, Jessie C, Dickan, Joseph N, Ahmadi, Sabrena M, Allen, Donald N, Mai, Van Thanh, Ansari, Saif, Yeh, George, Yoon, Earl, Gon, Kimberly, Yu, John Y, He, Johnny, Zaretsky, Jesse M, Lee, Noemi E, Kuoy, Edward, Patananan, Alexander N, Sitz, Daniel, Tran, PhuongThao, Do, Minh-Tu, Akhave, Samira J, Alvarez, Silverio D, Asem, Bobby, Asem, Neda, Azarian, Nicole A, Babaesfahani, Arezou, Bahrami, Ahmad, Bhamra, Manjeet, Bhargava, Ragini, Bhatia, Rakesh, Bhatia, Subir, Bumacod, Nicholas, Caine, Jonathan J, Caldwell, Thomas A, Calica, Nicole A, Calonico, Elise M, Chan, Carman, Chan, Helen H-L, Chang, Albert, Chang, Chiaen, Chang, Daniel, Chang, Jennifer S, Charania, Nauman, Chen, Jasmine Y, Chen, Kevin, Chen, Lu, Chen, Yuyu, Cheung, Derek J, Cheung, Jesse J, Chew, Jessica J, Chew, Nicole B, Chien, Cheng-An Tony, Chin, Alana M, Chin, Chee Jia, Cho, Youngho, Chou, Man Ting, Chow, Ke-Huan K, Chu, Carolyn, Chu, Derrick M, Chu, Virginia, Chuang, Katherine, Chugh, Arunit Singh, Cubberly, Mark R, Daniel, Michael Guillermo, Datta, Sangita, Dhaliwal, Raj, Dinh, Jenny, Dixit, Dhaval, Dowling, Emmylou, Feng, Melinda, From, Christopher M, Furukawa, Daisuke, Gaddipati, Himaja

“…A variety of genetic techniques have been devised to determine cell lineage relationships during tissue development. Some of these systems monitor cell…”
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LGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation by Tsai, Yu-Hwai, Hill, David R, Kumar, Namit, Huang, Sha, Chin, Alana M, Dye, Briana R, Nagy, Melinda S, Verzi, Michael P, Spence, Jason R

“…Background & Aims The Lgr family of transmembrane proteins (Lgr4, 5, 6) act as functional receptors for R-spondin proteins (Rspo 1, 2, 3, 4), and potentiate…”
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Elucidating a novel WNT/β-CATENIN signaling-independent environment that precedes villus morphogenesis in the embryonic intestine by Chin, Alana M

“…The intestine is a vital organ responsible for several functions, including excretion of waste, acting as a major site of host immunity, and most importantly,…”
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LGR4 and LGR5 Function Redundantly During Human Endoderm DifferentiationSummary by Yu-Hwai Tsai, David R. Hill, Namit Kumar, Sha Huang, Alana M. Chin, Briana R. Dye, Melinda S. Nagy, Michael P. Verzi, Jason R. Spence

“…Background & Aims: The Lgr family of transmembrane proteins (Lgr4, 5, 6) act as functional receptors for R-spondin proteins (Rspo 1, 2, 3, 4), and potentiate…”
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