Search Results - "Chimankar, Vrushali"
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Pre-clinical lung squamous cell carcinoma mouse models to identify novel biomarkers and therapeutic interventions
Published in Frontiers in oncology (25-09-2023)“…Primary lung carcinoma or lung cancer (LC) is classified into small-cell or non-small-cell (NSCLC) lung carcinoma. Lung squamous cell carcinoma (LSCC) is the…”
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Impact of Deleterious Mutations on Structure, Function and Stability of Serum/Glucocorticoid Regulated Kinase 1: A Gene to Diseases Correlation
Published in Frontiers in molecular biosciences (03-11-2021)“…Serum and glucocorticoid-regulated kinase 1 (SGK1) is a Ser/Thr protein kinase involved in regulating cell survival, growth, proliferation, and migration. Its…”
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Molecular links between COPD and lung cancer: new targets for drug discovery?
Published in Expert opinion on therapeutic targets (03-06-2019)“…COPD and lung cancer are leading causes of morbidity and mortality worldwide, and they share a common environmental risk factor in cigarette smoke exposure and…”
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Animal models of COPD: What do they tell us?
Published in Respirology (Carlton, Vic.) (01-01-2017)“…ABSTRACT COPD is a major cause of global mortality and morbidity but current treatments are poorly effective. This is because the underlying mechanisms that…”
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Recent advances in experimental animal models of lung cancer
Published in Future medicinal chemistry (01-04-2020)“…Lung cancer is typically a lethal malignancy, primarily due to delay in definitive clinical diagnosis and consequently has a poor prognosis (1). [...]there is…”
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Aim2 suppresses cigarette smoke‐induced neutrophil recruitment, neutrophil caspase‐1 activation and anti‐Ly6G‐mediated neutrophil depletion
Published in Immunology and cell biology (01-04-2022)“…Increased inflammasome responses are strongly implicated in inflammatory diseases; however, their specific roles are incompletely understood. Therefore, we…”
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Animal models of COPD : W hat do they tell us?
Published in Respirology (Carlton, Vic.) (01-01-2017)“…ABSTRACT COPD is a major cause of global mortality and morbidity but current treatments are poorly effective. This is because the underlying mechanisms that…”
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