Search Results - "Chillón, C"

Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling by Gutiérrez, N C, Sarasquete, M E, Misiewicz-Krzeminska, I, Delgado, M, De Las Rivas, J, Ticona, F V, Fermiñán, E, Martín-Jiménez, P, Chillón, C, Risueño, A, Hernández, J M, García-Sanz, R, González, M, San Miguel, J F

“…Specific microRNA (miRNA) signatures have been associated with different cytogenetic subtypes in acute leukemias. This finding prompted us to investigate…”
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Evolving patterns and clinical outcome of genetic studies performed at diagnosis in acute myeloid leukemia patients: Real life data from the PETHEMA Registry by Labrador, Jorge, Martínez‐Cuadrón, David, Boluda, Blanca, Serrano, Josefina, Gil, Cristina, Pérez‐Simón, José A., Bernal, Teresa, Bergua, Juan M., Martínez‐López, Joaquín, Rodríguez‐Medina, Carlos, Vidriales, María B., García‐Boyero, Raimundo, Algarra, Lorenzo, Polo, Marta, Sayas, María J., Tormo, Mar, Alonso‐Domínguez, Juan M., Herrera, Pilar, Lavilla, Esperanza, Ramos, Fernando, Amigo, María L., Vives‐Polo, Susana, Rodríguez‐Macías, Gabriela, Mena‐Durán, Armando, Pérez‐Encinas, Manuel M., Arce‐Fernández, Olga, Cuello, Rebeca, Sánchez‐García, Joaquín, Gómez‐Casares, María T., Chillón, María C., Calasanz, María J., Ayala, Rosa, Rodriguez‐Veiga, Rebeca, Barragán, Eva, Montesinos, Pau

“…Background There are no studies assessing the evolution and patterns of genetic studies performed at diagnosis in acute myeloid leukemia (AML) patients. Such…”
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The cryptic IRF2BP2-RARA fusion transforms hematopoietic stem/progenitor cells and induces retinoid-sensitive acute promyelocytic leukemia by Jovanovic, J V, Chillón, M C, Vincent-Fabert, C, Dillon, R, Voisset, E, Gutiérrez, N C, Sanz, R G, Lopez, A A M, Morgan, Y G, Lok, J, Solomon, E, Duprez, E, Díaz, M G, Grimwade, D

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Management of mixed acute rejection driven by a de novo donor-specific complement-binding anti-DQB103:01 antibody and intraepithelial CD8 T-cells in a kidney recipient: a case report by Boix, F, Feito, J, Rodríguez-Campón, A, Chillón, MC, García-Sánchez, S, Tabernero, G, Fraile, P, García-Sanz, R

“…Mixed acute rejection is a clinicopathological entity that is difficult to accurately diagnose, and so may be under-reported. Allografts are lost more often…”
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The predominant myeloma clone at diagnosis, CDR3 defined, is constantly detectable across all stages of disease evolution by Puig, N, Conde, I, Jiménez, C, Sarasquete, M E, Balanzategui, A, Alcoceba, M, Quintero, J, Chillón, M C, Sebastián, E, Corral, R, Marín, L, Gutiérrez, N C, Mateos, M-V, González-Díaz, M, San-Miguel, J F, García-Sanz, R

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Role of Intracellular Drug Disposition in the Response of Acute Myeloid Leukemia to Cytarabine and Idarubicin Induction Chemotherapy by Rodríguez-Macías, Gabriela, Briz, Oscar, Cives-Losada, Candela, Chillón, María C, Martínez-Laperche, Carolina, Martínez-Arranz, Ibon, Buño, Ismael, González-Díaz, Marcos, Díez-Martín, José L, Marin, Jose J G, Macias, Rocio I R

“…Despite its often low efficacy and high toxicity, the standard treatment for acute myeloid leukemia (AML) is induction chemotherapy with cytarabine and…”
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Molecular stratification model for prognosis in cytogenetically normal acute myeloid leukemia by Santamaría, Carlos M., Chillón, María C., García-Sanz, Ramón, Pérez, Cristina, Caballero, María D., Ramos, Fernando, de Coca, Alfonso García, Alonso, José M., Giraldo, Pilar, Bernal, Teresa, Queizán, José A., Rodriguez, Juan N., Fernández-Abellán, Pascual, Bárez, Abelardo, Peñarrubia, María J., Balanzategui, Ana, Vidriales, María B., Sarasquete, María E., Alcoceba, Miguel, Díaz-Mediavilla, Joaquín, San Miguel, Jesús F., Gonzalez, Marcos

“…We have evaluated 9 new molecular markers (ERG, EVI1, MLL-PTD, MN1, PRAME, RHAMM, and WT1 gene-expression levels plus FLT3 and NPM1 mutations) in 121 de novo…”
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Baseline immunophenotypic profile of bone marrow leukemia cells in acute myeloid leukemia with nucleophosmin-1 gene mutation: a EuroFlow study by Matarraz, Sergio, Leoz, Pilar, Yeguas-Bermejo, Ana, van der Velden, Vincent, Bras, Anne E., Sánchez Gallego, Jose I., Lecrevisse, Quentin, Ayala-Bueno, Rosa, Teodosio, Cristina, Criado, Ignacio, González-González, María, Flores-Montero, Juan, Avendaño, Alejandro, Vidriales, María B., Chillón, María C., González, Teresa, García-Sanz, Ramón, Prieto Conde, María I., Villamor, Neus, Magnano, Laura, Colado, Enrique, Fernández, Paula, Sonneveld, Edwin, Philippé, Jan, Reiterová, Michaela, Caballero Berrocal, Juan C., Diaz-Gálvez, Francisco J., Ramos, Fernando, Dávila Valls, Julio, Manjón Sánchez, Raquel, Solano Tovar, Jackeline, Calvo, Xavier, García Alonso, Luis, Arenillas, Leonor, Alonso, Sara, Fonseca, Ariana, Quirós Caso, Covadonga, van Dongen, Jacques J. M., Orfao, Alberto

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Upregulation of Dicer is more frequent in monoclonal gammopathies of undetermined significance than in multiple myeloma patients and is associated with longer survival in symptomatic myeloma patients by SARASQUETE, María E, GUTIERREZ, Norma C, MISIEWICZ-KRZEMINSKA, Irena, PAIVA, Bruno, CHILLON, Maria C, ALCOCEBA, Miguel, GARCIA-SANZ, Ramón, HERNANDEZ, Jesus M, GONZALEZ, Marcos, SAN-MIGUEL, Jesus F

“…Dicer and Drosha are key enzymes in the miRNA-processing pathway which is altered in many human cancers. We analyzed Dicer and Drosha expression levels by…”
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Comparison of the 2022 and 2017 European LeukemiaNet risk classifications in a real-life cohort of the PETHEMA group by Sargas, Claudia, Ayala, Rosa, Larráyoz, María J., Chillón, María C., Rodriguez-Arboli, Eduardo, Bilbao, Cristina, Prados de la Torre, Esther, Martínez-Cuadrón, David, Rodríguez-Veiga, Rebeca, Boluda, Blanca, Gil, Cristina, Bernal, Teresa, Bergua, Juan, Algarra, Lorenzo, Tormo, Mar, Martínez-Sánchez, Pilar, Soria, Elena, Serrano, Josefina, Alonso-Dominguez, Juan M., García, Raimundo, Amigo, María Luz, Herrera-Puente, Pilar, Sayas, María J., Lavilla-Rubira, Esperanza, Martínez-López, Joaquín, Calasanz, María J., García-Sanz, Ramón, Pérez-Simón, José A., Gómez Casares, María T., Sánchez-García, Joaquín, Barragán, Eva, Montesinos, Pau

“…Next-Generation Sequencing is needed for the accurate genetic risk stratification of acute myeloid leukemia according to European LeukemiaNet (ELN) guidelines…”
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MIPI53. A NEW PROGNOSTIC INDEX FOR MANTLE CELL LYMPHOMA by Boente, M. Bastos, Sánchez, M. Alcoceba, Bailón, A. Navarro, Herrera, A. Medina, Álvarez, M. García, Sarasquete, M. E. Alonso, Santos, C. Chillón, Echevarría, A. Balanzategui, Gómez, A. Antón, Niño, J., Loizaga, I. de la Torre, Bedera, N. H. Vidaña, Sánchez, R. Maldonado, Ruano, M. Hernández, Sánchez, S. M. Lucas, Villares, M. I. Sánchez, González, A. I. Sánchez, González de la Calle, V., Díaz, M. González, Sánchez, C. Jiménez, Sanz, R. García, García‐Sancho, A. Martín

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Correction: Standardisation and consensus guidelines for minimal residual disease assessment in Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL) by real-time quantitative reverse transcriptase PCR of e1a2 BCR-ABL1 by Pfeifer, H., Cazzaniga, G., van der Velden, V. H. J., Cayuela, J. M., Schäfer, B., Spinelli, O., Akiki, S., Avigad, S., Bendit, I., Borg, K., Cavé, H., Elia, L., Reshmi, S. C., Gerrard, G., Hayette, S., Hermanson, M., Juh, A., Jurcek, T., Chillón, M. C., Homburg, C., Martinelli, G., Kairisto, V., Lange, T., Lion, T., Mueller, M. C., Pane, F., Rai, L., Damm-Welk, C., Sacha, T., Schnittger, S., Touloumenidou, T., Valerhaugen, H., Vandenberghe, P., Zuna, J., Serve, H., Herrmann, E., Markovic, S., van Dongen, J. J. M., Ottmann, O. G.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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From Waldenström’s macroglobulinemia to aggressive diffuse large B-cell lymphoma: a whole-exome analysis of abnormalities leading to transformation by Jiménez, C, Alonso-Álvarez, S, Alcoceba, M, Ordóñez, G R, García-Álvarez, M, Prieto-Conde, M I, Chillón, M C, Balanzategui, A, Corral, R, Marín, L A, Gutiérrez, N C, Puig, N, Sarasquete, M E, González, M, García-Sanz, R

“…Transformation of Waldenström’s macroglobulinemia (WM) to diffuse large B-cell lymphoma (DLBCL) occurs in up to 10% of patients and is associated with an…”
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A Next-Generation Sequencing Strategy for Evaluating the Most Common Genetic Abnormalities in Multiple Myeloma by Jiménez, Cristina, Jara-Acevedo, María, Corchete, Luis A, Castillo, David, Ordóñez, Gonzalo R, Sarasquete, M. Eugenia, Puig, Noemí, Martínez-López, Joaquín, Prieto-Conde, M. Isabel, García-Álvarez, María, Chillón, M. Carmen, Balanzategui, Ana, Alcoceba, Miguel, Oriol, Albert, Rosiñol, Laura, Palomera, Luis, Teruel, Ana I, Lahuerta, Juan J, Bladé, Joan, Mateos, María V, Orfão, Alberto, San Miguel, Jesús F, González, Marcos, Gutiérrez, Norma C, García-Sanz, Ramón

“…Identification and characterization of genetic alterations are essential for diagnosis of multiple myeloma and may guide therapeutic decisions. Currently,…”
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Evaluating gene expression profiling by quantitative polymerase chain reaction to develop a clinically feasible test for outcome prediction in multiple myeloma by Sarasquete, María E., Martínez‐López, Joaquín, Chillón, María C., Alcoceba, Miguel, Corchete, Luis A., Paiva, Bruno, Puig, Noemi, Sebastián, Elena, Jiménez, Cristina, Mateos, Maria‐Victoria, Oriol, Albert, Rosiñol, Laura, Palomera, Luis, Teruel, Ana I., González, Yolanda, Lahuerta, Juan J., Bladé, Joan, Gutiérrez, Norma C., Fernández‐Redondo, Elena, González, Marcos, San Miguel, Jesús F., García‐Sanz, Ramón

“…Summary The gene expression profiles (GEPs) of 96 selected genes were analysed by real‐time quantitative polymerase chain reaction (qPCR) with a TaqMan…”
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Quantitative PCR: an alternative approach to detect common copy number alterations in multiple myeloma by Chillón, M. C., Jiménez, C., García-Sanz, R., Alcoceba, M., Prieto, I., García-Alvarez, M., Antón, A., Maldonado, R., Hernández-Ruano, M., González, M., Gutiérrez, N. C., Sarasquete, M. E.

“…Chromosome 1q gains and 13q deletions are common cytogenetic aberrations in multiple myeloma (MM) that confer a poor prognosis. There are several techniques…”
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Differentiation with Raman spectroscopy among several natural ultramarine blues and the synthetic ultramarine blue used by the Catalonian modernist painter Ramon Casas i Carbó by De Torres, A. R., Ruiz-Moreno, S., López-Gil, A., Ferrer, P., Chillón, M. C.

“…This paper investigates, using only Raman spectroscopy, the spectral differences among the synthetic ultramarine blue (J. B. Guimet) and three natural…”
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BAALC is an important predictor of refractoriness to chemotherapy and poor survival in intermediate-risk acute myeloid leukemia (AML) by Santamaría, Carlos, Chillón, María C, García-Sanz, Ramón, Pérez, Cristina, Caballero, María D, Mateos, María V, Ramos, Fernando, de Coca, Alfonso García, Alonso, José M, Giraldo, Pilar, Bernal, Teresa, Queizán, José A, Rodríguez, Juan N, Puig, Noemí, Balanzategui, Ana, Sarasquete, María E, Alcoceba, Miguel, Díaz-Mediavilla, Joaquín, San Miguel, Jesús, González, Marcos

“…We have analyzed brain and acute leukemia, cytoplasmic (BAALC) gene expression and other genetic markers (ERG, EVI1, MN1, PRAME, WT1, FLT3, and NPM1 mutations)…”
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Chronic GVHD Could Ameliorate the Impact of Adverse Somatic Mutations in Patients with Myelodysplastic Syndromes and Hematopoietic Stem Cell Transplantation by Caballero Berrocal, J.C, Sánchez Barba, M, Hernández Sánchez, J.M, Del Rey, M, Janusz, K, Chillón, C, Such, E, Sanz, G, Hurtado, A.M, Calderón Cabrera, C, Valcárcel, D, Lumbreras, E, Robledo, C, Abáigar, M, López Cadenas, F, Cabrero, M, Redondo-Guijo, A, Hernández Rivas, J.M, Del Cañizo, M.C, Díez Campelo, M

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The use of CD138 positively selected marrow samples increases the applicability of minimal residual disease assessment by PCR in patients with multiple myeloma by Puig, Noemí, Sarasquete, María E., Alcoceba, Miguel, Balanzategui, Ana, Chillón, María C., Sebastián, Elena, Marín, Luis A., Díaz, Marcos González, San Miguel, Jesús F., Sanz, Ramón García

“…We have evaluated the use of CD138+ positively selected bone marrow samples to identify a molecular target for minimal residual disease assessment by…”
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