Search Results - "Childers, Karla G"

Suzuki-Miyaura Cross-Coupling of 2-Nitroarenediazonium Tetrafluoroborates: Synthesis of Unsymmetrical 2-Nitrobiphenyls and Highly Functionalized Carbazoles by Kuethe, Jeffrey T., Childers, Karla G.

“…The Suzuki–Miyaura cross‐coupling of 2‐nitrodiazonium tetrafluoroborate salts with substituted boronic acids is an effective and efficient means of preparing…”
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Asymmetric Synthesis of a Potent HIV‑1 Integrase Inhibitor by Kuethe, Jeffrey T, Humphrey, Guy R, Journet, Michel, Peng, Zhihui, Childers, Karla G

“…The development of a practical asymmetric total synthesis of the potent HIV-1 integrase inhibitor 5 is described. Key transformations include construction of…”
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A Rapid, Large-Scale Synthesis of a Potent Cholecystokinin (CCK) 1R Receptor Agonist by Kuethe, Jeffrey T, Childers, Karla G, Humphrey, Guy R, Journet, Michel, Peng, Zhihui

“…The development of a scalable synthesis of a potent cholecystokinin (CCK) 1R receptor agonist is described. The focus on a rapid short-term delivery rather…”
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A Practical, Kilogram-Scale Implementation of the Wolff−Kishner Reduction by Kuethe, Jeffrey T, Childers, Karla G, Peng, Zhihui, Journet, Michel, Humphrey, Guy R, Vickery, Thomas, Bachert, Donald, Lam, Thientu T

“…A safe and practical strategy has been developed for the large-scale preparation of imidazole 7. The key transformation involved the Wolff−Kishner reduction of…”
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A Practical and Scaleable Preparation of 1,4-Anhydroerythritol by Childers, Karla G, Dreher, Spencer D, Lee, Jaemoon, Williams, J. Michael

“…A practical and efficient kilogram-scale preparation of 1,4-anhydroerythritol from meso-erythritol is described. A novel silica gel and sodium bicarbonate…”
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Rearrangement of spiro-benzimidazolines: preparation of N-alkenyl- and N-alkyl-benzimidazol-2-ones by Kuethe, Jeffrey T., Varon, Jack, Childers, Karla G.

“…A synthetically useful protocol has been developed for the preparation of highly functionalized N-alkenyl-benzimidazol-2-ones. Reaction of commercially…”
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