Search Results - "Chilcote, J"
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Red blood cells are the major source of alpha-synuclein in blood
Published in Neuro-degenerative diseases (01-01-2008)“…Alpha-synuclein has been directly linked to Parkinson's disease etiology by mutations in and multiplication of its gene that result in a familial form of…”
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Plasma Kallikrein Mediates Retinal Vascular Dysfunction and Induces Retinal Thickening in Diabetic Rats
Published in Diabetes (New York, N.Y.) (01-05-2011)“…Plasma kallikrein (PK) has been identified in vitreous fluid obtained from individuals with diabetic retinopathy and has been implicated in contributing to…”
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Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein
Published in Nature medicine (01-02-2011)“…Hyperglycemia is associated with greater hematoma expansion and poor clinical outcomes after intracerebral hemorrhage. We show that cerebral hematoma expansion…”
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4
Plasma Kallikrein Mediates Angiotensin II Type 1 Receptor–Stimulated Retinal Vascular Permeability
Published in Hypertension (Dallas, Tex. 1979) (01-02-2009)“…Hypertension is a leading risk factor for the development and progression of diabetic retinopathy and contributes to a variety of other retinal diseases in the…”
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5
Lack of Correlation between Caspase Activation and Caspase Activity Assays in Paclitaxel-treated MCF-7 Breast Cancer Cells
Published in The Journal of biological chemistry (04-01-2002)“…MCF-7 human breast cancer cells are widely utilized to study apoptotic processes. Recent studies demonstrated that these cells lack procaspase-3. In the…”
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Phosphorylation of Ser-129 Is the Dominant Pathological Modification of α-Synuclein in Familial and Sporadic Lewy Body Disease
Published in The Journal of biological chemistry (06-10-2006)“…A comprehensive, unbiased inventory of synuclein forms present in Lewy bodies from patients with dementia with Lewy bodies was carried out using…”
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rbSec1A and B Colocalize with Syntaxin 1 and SNAP-25 Throughout the Axon, but Are Not in a Stable Complex with Syntaxin
Published in The Journal of cell biology (01-04-1995)“…rbSec1 is a mammalian neuronal protein homologous to the yeast SEC1 gene product which is required for exocytosis. Mutations in Sec1 homologues in the nervous…”
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Interaction of Grb2 via its Src Homology 3 Domains with Synaptic Proteins Including Synapsin I
Published in Proceedings of the National Academy of Sciences - PNAS (05-07-1994)“…Grb2 is a 25-kDa adaptor protein composed of a Src homology 2 (SH2) domain and two flanking Src homology 3 (SH3) domains. One function of Grb2 is to couple…”
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Polo-like Kinase 2 (PLK2) Phosphorylates α-Synuclein at Serine 129 in Central Nervous System
Published in The Journal of biological chemistry (30-01-2009)“…Several neurological diseases, including Parkinson disease and dementia with Lewy bodies, are characterized by the accumulation of α-synuclein phosphorylated…”
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Cellubrevin and Synaptobrevins: Similar Subcellular Localization and Biochemical Properties in PC12 Cells
Published in The Journal of cell biology (01-04-1995)“…There is strong evidence to indicate that proteins of the synaptobrevin family play a key role in exocytosis. Synaptobrevin 1 and 2 are expressed at high…”
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Discovery and spectroscopy of the young jovian planet 51 Eri b with the Gemini Planet Imager
Published in Science (American Association for the Advancement of Science) (02-10-2015)“…Directly detecting thermal emission from young extrasolar planets allows measurement of their atmospheric compositions and luminosities, which are influenced…”
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12
Synapsin I regulates glutamate release from rat brain synaptosomes
Published in Journal of neurochemistry (01-02-1992)“…Introduction of the dephosphorylated from of synapsin I into rat brain synaptosomes using freeze-thaw (transient) permeabilization significantly decreased the…”
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Characterization of caspase processing and activation in HL-60 cell cytosol under cell-free conditions. Nucleotide requirement and inhibitor profile
Published in The Journal of biological chemistry (06-08-1999)“…The present studies compared caspase activation under cell-free conditions in vitro and in etoposide-treated HL-60 leukemia cells in situ. Immunoblotting…”
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14
Phosphorylation of Tetrahymena 22 S dynein
Published in The Journal of biological chemistry (05-10-1990)“…Studies involving 32P labeling and wet ashing of isolated dynein reveal that isolated dynein contains approximately 6 mol of phosphate predominantly…”
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15
Synapsin IIa: expression in insect cells, purification, and characterization
Published in Biochemistry (Easton) (05-05-1992)“…Synapsin IIa belongs to a family of neuron-specific phosphoproteins called synapsins, which are associated with synaptic vesicles in presynaptic nerve…”
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Synapsin IIa bundles actin filaments
Published in Journal of neurochemistry (01-10-1994)“…Synapsins are neuron-specific phosphoproteins associated with small synaptic vesicles in the presynaptic nerve terminal. Synapsin I, which has been…”
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Discovery and spectroscopy of the young Jovian planet 51 Eri b with the Gemini Planet Imager
Published 09-10-2015“…Macintosh et al., Science 350 (6256): 64-67, 2015 Directly detecting thermal emission from young extrasolar planets allows measurement of their atmospheric…”
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18
Localization of cellubrevin to the Golgi complex in pancreatic acinar cells
Published in European journal of cell biology (01-08-1996)“…Cellubrevin is the smallest (14 kDa) isoform of the synaptobrevin (VAMP) protein family and is found in a wide variety of tissues. Western blot analysis with a…”
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Characterization of Caspase Processing and Activation in HL-60 Cell Cytosol Under Cell-free Conditions
Published in The Journal of biological chemistry (06-08-1999)“…The present studies compared caspase activation under cell-free conditions in vitro and in etoposide-treated HL-60 leukemia cells in situ . Immunoblotting…”
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v- and t-SNAREs in neuronal exocytosis: A need for additional components to define sites of release
Published in Neuropharmacology (01-11-1995)“…Synaptic vesicle recycling is a specialized form of membrane recycling which takes place in all cells between early endosomes and the plasmalemma. Synaptic…”
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