Search Results - "Chikkala, NF"

Markedly Elevated Levels of Interferon (IFN)-γ, IFN-α, Interleukin (IL)-2, IL-10, and Tumor Necrosis Factor-α Associated with Fatal Ebola Virus Infection by Villinger, Francois, Rollin, Pierre E., Brar, Sukhdev S., Chikkala, Nathaniel F., Winter, Jorn, Sundstrom, J. Bruce, Zaki, Sherif R., Swanepoel, Robert, Ansari, Aftab A., Peters, Clarence J.

“…The role of immune mechanisms in the pathogenesis of Ebola hemorrhagic fever (EHF) remains to be elucidated. In this report, the serum cytokine levels of…”
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Anti-inflammatory action of IL-4. Negative regulation of contact sensitivity to trinitrochlorobenzene by Gautam, SC, Chikkala, NF, Hamilton, TA

“…We examined the effects of IL-4, a cytokine produced by Th2 cells, on the development of an Ag-specific, T cell-mediated inflammatory response in a…”
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In vitro and in vivo responses to interleukin 12 are maintained until the late SIV infection stage but lost during AIDS by Villinger, F, Bucur, S, Chikkala, N F, Brar, S S, Bostik, P, Mayne, A E, Adams, J, Lee, M E, Novembre, F J, Gately, M K, Ansari, A A, Hillyer, C D

“…The in vitro proliferative responses of macaque peripheral blood mononuclear cells (PBMCs) to IL-12 appeared similar before and early after SIV infection,…”
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Induction of Long-Term Protective Effects against Heterologous Challenge in SIVhu-Infected Macaques by Villinger, François, Switzer, William M., Parekh, Bharat S., Otten, Ronald A., Adams, Debra, Shanmugam, Vedapuri, Bostik, Pavel, Mayne, Ann E., Chikkala, Nathaniel F., McClure, Harold M., Novembre, Francis, Yao, Qizhi, Heneine, Walid, Folks, Thomas M., Ansari, Aftab A.

“…A group of three rhesus macaques were inoculated with SIV isolated from a human (SIVhu) accidentally exposed and infected with SIVsm. Extensive sequence…”
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Interactive effects of α-interferon A/D and interleukin 2 on murine lymphokine-activated killer activity : analysis at the effector and precursor level by CHIKKALA, N. F, LEWIS, I, ULCHAKER, J, STANLEY, J, TUBBS, R, FINKE, J. H

“…Studies from our laboratory and others have demonstrated that alpha-interferon (IFN alpha) can regulate natural killer cells and lymphokine-activated killer…”
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Immune and hematopoietic parameters in HIV-1-infected chimpanzees during clinical progression toward AIDS by Villinger, Francois, Brar, Sukhdev S., Brice, Gary T., Chikkala, Nathaniel F., Novembre, Francis J., Mayne, Ann E., Bucur, Silvana, Hillyer, Christopher D., Ansari, Aftab A.

“…: Until recently, chimpanzees were considered susceptible to human immunodeficiency virus type 1 (HIV‐1) infection, but refractory to disease induction based…”
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Oral administration of the contact sensitizer trinitrochlorobenzene: initial sensitization and subsequent appearance of a suppressor population by Gautam, S C, Chikkala, N F, Battisto, J R

“…Our earlier studies have demonstrated that intragastric administration of the hapten trinitrochlorobenzene (TNCB) 2 to 3 weeks prior to attempting…”
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Combination therapy with adriamycin and interleukin 2 augments immunity against murine renal cell carcinoma by Gautam, S C, Chikkala, N F, Ganapathi, R, Hamilton, T A

“…The mechanism(s) through which combination treatment with Adriamycin and recombinant interleukin 2 (rIL2) affects murine renal cell carcinoma was investigated…”
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Expression and in vitro evaluation of rhesus macaque wild type (wt) and modified CC chemokines by Bostik, Pavel, Villinger, Francois, Brice, Gary T., Chikkala, Nathaniel F., Brar, Sukhdev S., Cruikshank, William W., Adams, Jonathan W., Hillyer, Christopher D., Ansari, Aftab A.

“…: Several human CC chemokines have been shown to inhibit HIV/SIV infection in vitro, providing the rationale for their potential use in vivo. However, because…”
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Differences in murine gut-associated lymphoid tissues in generating broadly nonspecific cytotoxic cells in response to interferon alpha A/D and interleukin 2 by Chikkala, N F, Gautam, S C

“…We examined the response of cells of murine gut-associated lymphoid tissues to agents that augment the activity of natural killer (NK) cells. Specifically, we…”
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Therapeutic efficacy of interleukin-2 activated killer cells against adriamycin resistant mouse B16-BL6 melanoma by Gautam, S C, Chikkala, N F, Lewis, I, Grabowski, D R, Finke, J H, Ganapathi, R

“…Development of multidrug-resistance (MDR) remains a major cause of failure in the treatment of cancer with chemotherapeutic agents. In our efforts to explore…”
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