Search Results - "Chikamatsu, Mayuko"
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Albumin-fused long-acting FGF21 analogue for the treatment of non-alcoholic fatty liver disease
Published in Journal of controlled release (01-03-2023)“…Non-alcoholic fatty liver disease (NAFLD) currently affects about 25% of the world's population, and the numbers continue to rise as the number of obese…”
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Cell-penetrating albumin enhances the sublingual delivery of antigens through macropinocytosis
Published in International journal of biological macromolecules (30-11-2022)“…Innovations in oral immunotherapy have greatly advanced the therapeutic control of allergies. However, these therapeutic effects suffer from the fact that the…”
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Advanced Oxidation Protein Products Contribute to Chronic-Kidney-Disease-Induced Adipose Inflammation through Macrophage Activation
Published in Toxins (26-02-2023)“…Fat atrophy and adipose tissue inflammation can cause the pathogenesis of metabolic symptoms in chronic kidney disease (CKD). During CKD, the serum levels of…”
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Albumin-fused thioredoxin ameliorates high-fat diet-induced non-alcoholic steatohepatitis
Published in Heliyon (15-02-2024)“…The pathogenesis of non-alcoholic steatohepatitis (NASH) involves the simultaneous interaction of multiple factors such as lipid accumulation, oxidative…”
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5
Development of a long acting FGF21 analogue-albumin fusion protein and its anti-diabetic effects
Published in Journal of controlled release (10-08-2020)“…Fibroblast growth factor 21 (FGF21) is a hormone-like protein that improves blood glucose and lipid metabolism. However, its short half-life and instability…”
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Involvement of the Parathyroid Hormone-Related Protein on Changes in the CYP3A Expression in Cancer Cachexia
Published in Molecular pharmaceutics (06-12-2021)“…Parathyroid hormone-related protein (PTHrP), which is secreted from a tumor, contributes to the progression of cachexia, a condition that is observed in half…”
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