Search Results - "Chik, C. L."
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1
Impact of gestational diabetes mellitus and high maternal weight on the development of diabetes, hypertension and cardiovascular disease: a population-level analysis
Published in Diabetic medicine (01-02-2015)“…Aims To examine the association between gestational diabetes mellitus (GDM) and high maternal weight and the risk of development of chronic disease. Methods…”
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2
A practical, clinical approach to the assessment and management of suspected insulin allergy
Published in Diabetic medicine (01-08-2013)“…Background Although allergic reactions to insulin are uncommon, they can be difficult to diagnose and management may be very difficult in subjects with Type 1…”
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Sustained Adrenergic Stimulation Is Required for the Nuclear Retention of TORC1 in Male Rat Pinealocytes
Published in Endocrinology (Philadelphia) (01-09-2013)“…The process involved in relocation of the coactivator, transducer of regulated cAMP-regulated element-binding protein (TORC) to the cytoplasm, unlike its…”
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Different Signaling Mechanisms Are Involved in the Norepinephrine-Stimulated TORC1 and TORC2 Nuclear Translocation in Rat Pinealocytes
Published in Endocrinology (Philadelphia) (01-08-2012)“…The distribution of transducers of regulated cAMP-response element-binding protein activity (TORC) between the cytoplasm and the nucleus is tightly regulated…”
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5
Salt-Inducible Kinase 1 in the Rat Pinealocyte: Adrenergic Regulation and Role in Arylalkylamine N-Acetyltransferase Gene Transcription
Published in Endocrinology (Philadelphia) (01-09-2009)“…The recognition of the basic leucine zipper domain in the regulation of transcriptional activity of cAMP response element-binding protein by salt-inducible…”
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Adrenergic Regulation of the Distribution of Transducer of Regulated cAMP-Response Element-Binding Protein (TORC2) in Rat Pinealocytes
Published in Endocrinology (Philadelphia) (01-09-2011)“…Transducers of regulated cAMP-response element-binding protein (CREB) activity (TORC) are coactivators that can increase CREB transcriptional activity,…”
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Nocturnal Activation of Aurora C in Rat Pineal Gland: Its Role in the Norepinephrine-Induced Phosphorylation of Histone H3 and Gene Expression
Published in Endocrinology (Philadelphia) (01-05-2009)“…We have shown previously that Ser10 phosphorylation of histone H3 occurs in rat pinealocytes after stimulation with norepinephrine (NE) and that histone…”
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8
Acetylation of Histone H3 and Adrenergic-Regulated Gene Transcription in Rat Pinealocytes
Published in Endocrinology (Philadelphia) (01-10-2007)“…In this study we investigated the effect of histone acetylation on the transcription of adrenergic-induced genes in rat pinealocytes. We found that treatment…”
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The Role of Repressor Proteins in the Adrenergic Induction of Type II Iodothyronine Deiodinase in Rat Pinealocytes
Published in Endocrinology (Philadelphia) (01-07-2007)“…In this study, we investigated the transcriptional regulation of the adrenergic induction of type II iodothyronine deiodinase (Dio2) in rat pinealocytes…”
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10
The Role of Inducible Repressor Proteins in the Adrenergic Induction of Arylalkylamine-N-Acetyltransferase and Mitogen-Activated Protein Kinase Phosphatase-1 in Rat Pinealocytes
Published in Endocrinology (Philadelphia) (01-02-2007)“…In this study, we investigated the role of two inducible repressor proteins, inducible cAMP early repressor (ICER) and Fos-related antigen 2 (Fra-2) in the…”
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11
Adrenergic Regulation and Diurnal Rhythm of p38 Mitogen-Activated Protein Kinase Phosphorylation in the Rat Pineal Gland
Published in Endocrinology (Philadelphia) (01-11-2004)“…In this study, we investigated adrenergic and photoneural regulation of p38MAPK phosphorylation in the rat pineal gland. Norepinephrine (NE), the endogenous…”
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12
Histone H3 Phosphorylation in the Rat Pineal Gland: Adrenergic Regulation and Diurnal Variation
Published in Endocrinology (Philadelphia) (01-04-2007)“…In this study, we investigated phosphorylation of Ser10 in histone H3 by norepinephrine (NE) in the rat pineal gland. In whole-animal studies, we demonstrated…”
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13
Inhibition of p38 Mitogen-Activated Protein Kinase Enhances Adrenergic-Stimulated Arylalkylamine N-Acetyltransferase Activity in Rat Pinealocytes
Published in Endocrinology (Philadelphia) (01-03-2004)“…We have previously shown that inhibition of p38MAPK increases adrenergic-stimulated p42/44MAPK activation in rat pinealocytes. In this study we investigated…”
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14
Regulation of 90-Kilodalton Ribosomal S6 Kinase Phosphorylation in the Rat Pineal Gland
Published in Endocrinology (Philadelphia) (01-08-2003)“…In this study we investigated diurnal changes in the activation state of the 90-kDa ribosomal S6 kinase (p90RSK) in the rat pineal gland. In animals housed…”
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15
Maintenance of Serum Calcium by Parathyroid Hormone-Related Peptide During Lactation in a Hypoparathyroid Patient
Published in The journal of clinical endocrinology and metabolism (01-02-1999)“…We describe the changes in calcium homeostasis seen in a hypoparathyroid woman during the third trimester and with lactation following her second pregnancy…”
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16
Role of protein turnover in the activation of p38 mitogen-activated protein kinase in rat pinealocytes
Published in Biochemical pharmacology (05-12-2005)“…Differences in the time profiles of activation between p38MAPK and p42/44MAPK by norepinephrine (NE) in rat pinealocytes suggest involvement of mechanisms…”
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17
Ceramide inhibits the outward potassium current in rat pinealocytes
Published in Journal of neurochemistry (01-10-2001)“…In the present study, we investigated the effect of ceramide on the outward K+ current in rat pinealocytes using whole cell and single channel recordings…”
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18
3′,5′‐Cyclic Guanosine Monophosphate Activates Mitogen‐Activated Protein Kinase in Rat Pinealocytes
Published in Journal of neurochemistry (01-08-1999)“…: The role of 3′,5′‐cyclic guanosine monophosphate (cGMP) in the activation of mitogen‐activated protein kinases (MAPKs) was investigated in rat pinealocytes…”
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19
Timing of mitogen-activated protein kinase (MAPK) activation in the rat pineal gland
Published in Molecular and cellular endocrinology (27-06-2006)“…Activation of members of the mitogen-activated protein kinase (MAPK) family of signaling cascades is a tightly controlled event in rat pinealocytes. Cell…”
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The adrenergic-regulated CRTC1 and CRTC2 phosphorylation and cellular distribution is independent of endogenous SIK1 in the male rat pinealocyte
Published in Molecular and cellular endocrinology (15-10-2015)“…Salt inducible kinase 1 (SIK1) has been reported to repress cAMP-response element binding protein (CREB)-mediated gene transcription by causing the nuclear…”
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