Search Results - "Chihara, K."

GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults by Allen, D B, Backeljauw, P, Bidlingmaier, M, Biller, B M K, Boguszewski, M, Burman, P, Butler, G, Chihara, K, Christiansen, J, Cianfarani, S, Clayton, P, Clemmons, D, Cohen, P, Darendeliler, F, Deal, C, Dunger, D, Erfurth, E M, Fuqua, J S, Grimberg, A, Haymond, M, Higham, C, Ho, K, Hoffman, A R, Hokken-Koelega, A, Johannsson, G, Juul, A, Kopchick, J, Lee, P, Pollak, M, Radovick, S, Robison, L, Rosenfeld, R, Ross, R J, Savendahl, L, Saenger, P, Toft Sorensen, H, Stochholm, K, Strasburger, C, Swerdlow, A, Thorner, M

“…Recombinant human GH (rhGH) has been in use for 30 years, and over that time its safety and efficacy in children and adults has been subject to considerable…”
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High-Accuracy and Robust Localization of Large Control Markers for Geometric Camera Calibration by Douxchamps, D., Chihara, K.

“…Accurate measurement of the position of features in an image is subject to a fundamental compromise: The features must be both small, to limit the effect of…”
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Rho‐associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho by Matsui, T., Amano, M., Yamamoto, T., Chihara, K., Nakafuku, M., Ito, M., Nakano, T., Okawa, K., Iwamatsu, A., Kaibuchi, K.

“…The small GTP binding protein Rho is implicated in cytoskeletal responses to extracellular signals such as lysophosphatidic acid to form stress fibers and…”
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Statin suppresses apoptosis in osteoblastic cells: role of transforming growth factor-beta-Smad3 pathway by Kaji, H, Naito, J, Inoue, Y, Sowa, H, Sugimoto, T, Chihara, K

“…Statins possess pleiotropic effects in several tissues. Among them, their bone anabolic actions have been recently noted. We have proposed that Smad3, a…”
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Real-time gesture recognition by learning and selective control of visual interest points by Kirishima, T., Sato, K., Chihara, K.

“…For the real-time recognition of unspecified gestures by an arbitrary person, a comprehensive framework is presented that addresses two important problems in…”
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Primary porcine Kupffer cell phagocytosis of human platelets involves the CD18 receptor by Chihara, Ray K, Paris, Leela L, Reyes, Luz M, Sidner, Richard A, Estrada, Jose L, Downey, Susan M, Wang, Zheng-Yu, Tector, A Joseph, Burlak, Christopher

“…Hepatic failure has been treated successfully with clinical extracorporeal perfusions of porcine livers. However, dog-to-pig and pig-to-baboon liver…”
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Fibronectin from alpha 1,3-galactosyltransferase knockout pigs is a xenoantigen by Chihara, Ray K., MD, Lutz, Andrew J., MD, Paris, Leela L., PhD, Wang, Zheng-Yu, MD, PhD, Sidner, Richard A., PhD, Heyrman, Alex T., BS, Downey, Susan M., AA, Burlak, Christopher, PhD, Tector, A. Joseph, MD, PhD

“…Abstract Background Antibody-mediated rejection continues to be an obstacle for xenotransplantation despite development of α1,3-galactosyltransferase knockout…”
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Testosterone increases osteoprotegerin mRNA expression in mouse osteoblast cells by Chen, Q, Kaji, H, Kanatani, M, Sugimoto, T, Chihara, K

“…The role that androgens play in the regulation of bone metabolism has been substantiated in animals and humans. We previously demonstrated that testosterone…”
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Smad3 differently affects osteoblast differentiation depending upon its differentiation stage by Kaji, H, Naito, J, Sowa, H, Sugimoto, T, Chihara, K

“…Smad3, a critical component of the TGF-beta signaling pathways, plays an important role in the regulation of bone formation. However, how Smad3 affects…”
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Serum levels of insulin-like growth factor (IGF); IGF-binding proteins-3, -4, and -5; and their relationships to bone mineral density and the risk of vertebral fractures in postmenopausal women by Yamaguchi, T, Kanatani, M, Yamauchi, M, Kaji, H, Sugishita, T, Baylink, D J, Mohan, S, Chihara, K, Sugimoto, T

“…We previously found that serum levels of insulin-like growth factor I (IGF-I) and IGF-binding protein (IGFBP)-3, but not IFGBP-2, were associated with bone…”
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Lobectomy Provides the Best Survival for Stage I Lung Cancer Patients Despite Advanced Age by Chan, Edward Y., Amirkhosravi, Farshad, Nguyen, Duc T., Chihara, Ray K., Graviss, Edward A., Kim, Min P.

“…The Lung Cancer Study Group has shown that lobectomy provides the best survival in patients with non–small cell lung cancer. However, as patients become older,…”
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BIN2 Functions Redundantly with Other Arabidopsis GSK3-Like Kinases to Regulate Brassinosteroid Signaling by Yan, Zhenyan, Zhao, Jun, Peng, Peng, Chihara, Ray K, Li, Jianming

“…GLYCOGEN SYNTHASE KINASE3 (GSK3) is a highly conserved serine/threonine kinase involved in a variety of developmental signaling processes. The Arabidopsis…”
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Lung resection for patients with lung cancer and chronic obstructive pulmonary disease by Nishikawa, S, Chihara, K

“…The number of lung resection for patients with lung cancer has been increasing lineally for last two decades in Japan. It reached more than 30,000 in 2009…”
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Decrease in vitamin D receptor and calcium-sensing receptor in highly proliferative parathyroid adenomas by Yano, S, Sugimoto, T, Tsukamoto, T, Chihara, K, Kobayashi, A, Kitazawa, S, Maeda, S, Kitazawa, R

“…OBJECTIVE: A significant decrease in vitamin D receptor (VDR) and calcium-sensing receptor (CaSR) protein expression has been demonstrated recently in…”
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Robot-assisted hiatal hernia repair demonstrates favorable short-term outcomes compared to laparoscopic hiatal hernia repair by Soliman, Basem G., Nguyen, Duc T., Chan, Edward Y., Chihara, Ray K., Meisenbach, Leonora M., Graviss, Edward A., Kim, Min P.

“…Background We postulated that the use of robotics may improve outcomes in hiatal hernia repair. Methods We performed a retrospective analysis of a…”
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G Protein-Coupled Cholecystokinin-B/Gastrin Receptors are Responsible for Physiological Cell Growth of the Stomach Mucosa in vivo by Nagata, Aki, Ito, Mitsuhiro, Iwata, Nobuko, Kuno, Junko, Takano, Hiroshi, Minowa, Osamu, Chihara, Kazuo, Matsui, Toshimitsu, Noda, Tetsuo

“…Many peptide hormone and neurotransmitter receptors belonging to the seven membrane-spanning G protein-coupled receptor family have been shown to transmit…”
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Intraoperative diagnosis and treatment of Achalasia using EndoFLIP during Heller Myotomy and Dor fundoplication by Law, Yi Ying, Nguyen, Duc T., Meisenbach, Leonora M., Chihara, Ray K., Chan, Edward Y., Graviss, Edward A., Kim, Min P.

“…Background Manometry is the gold standard diagnostic test for achalasia. However, there are incidences where manometry cannot be obtained preoperatively, or…”
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Laparoscopic Approach for Treatment of Symptomatic Intra-Pericardial Cyst by Chihara, Ray K., Force, Seth D.

“…Symptomatic pericardial cysts requiring operative management are rare entities. We present a patient with a symptomatic intra-pericardial cystic lesion with…”
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Double knockout pigs deficient in N-glycolylneuraminic acid and Galactose α-1,3-Galactose reduce the humoral barrier to xenotransplantation by Lutz, Andrew J., Li, Ping, Estrada, Jose L., Sidner, Richard A., Chihara, Ray K., Downey, Susan M., Burlak, Christopher, Wang, Zheng-Yu, Reyes, Luz M., Ivary, Bess, Yin, Fuqin, Blankenship, Ross L., Paris, Leela L., Tector, A. Joseph

“…Background Clinical xenotransplantation is not possible because humans possess antibodies that recognize antigens on the surface of pig cells. Galα‐1,3‐Gal…”
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Determinants of bone mineral density and spinal fracture risk in postmenopausal Japanese women by NAKAOKA, D, SUGIMOTO, T, KAJI, H, KANZAWA, M, YANO, S, YAMAUCHI, M, SUGISHITA, T, CHIHARA, K

“…The present study analyzed the factors that determine bone mineral density (BMD) and predict spinal fracture risk in postmenopausal Japanese women. Two hundred…”
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